Paralogous series of species-specific genes

Fam. size	Protein family	CDS	Short description
			
Z. rouxii
2	GL3C3673	ZYRO0C10120g	no similarity
Ê	Ê	ZYRO0F02728g	some similarities with SACE YIR019C MUC1 GPI-anchored cell surface glycoprotein
2	GL3C3937	ZYRO0E10428g	similar to SACE YDR539W 
Ê	Ê	ZYRO0G00198g	some similarities with SACE YDR539W
2	GL3C4506	ZYRO0D16918g	no similarity
Ê	Ê	ZYRO0F11132g	no similarity
2	GL3R4028 (1)	ZYRO0E10340g	highly similar to Aspergillus oryzae AO090012000349 Choline dehydrogenase and related flavoproteins
Ê	Ê	ZYRO0F18634g	highly similar to Aspergillus oryzae AO090012000349 Choline dehydrogenase and related flavoproteins
2	GL3R4324 (1)	ZYRO0A13552g	similar to Aspergillus oryzae AO090005000547 Predicted protein
Ê	Ê	ZYRO0G22572g	similar to Aspergillus oryzae AO090005000547 Predicted protein
3	GL3C3802	ZYRO0C01100g	some similarities with SACE YML111W BUL2 Component of the Rsp5p E3- ubiquitin ligase complex
		ZYRO0C05874g	some similarities with SACE YML111W BUL2 Component of the Rsp5p E3- ubiquitin ligase complex
Ê	Ê	ZYRO0C05896g	some similarities with SACE YML111W BUL2 Component of the Rsp5p E3- ubiquitin ligase complex 
3	GL3C4103	ZYRO0C18326g	some similarities with SACE YPR065W
		ZYRO0F15796g	no similarity
Ê	Ê	ZYRO0F18546g	no similarity
5	GL3C3825	ZYRO0A10868g	no similarity
		ZYRO0D09658g	no similarity
		ZYRO0E04774g	no similarity
		ZYRO0G10230g	no similarity
Ê	Ê	ZYRO0G10692g	no similarity
10	GL3R0925	ZYRO0A00154g	no similarity
		ZYRO0A00264g	no similarity
		ZYRO0A11374g	no similarity
		ZYRO0A13838g	no similarity
		ZYRO0A13904g	no similarity
		ZYRO0B00132g	no similarity
		ZYRO0C00220g	no similarity
		ZYRO0E00308g	no similarity
		ZYRO0F05434g	no similarity
Ê	Ê	ZYRO0G00154g	no similarity
20	GL3R0233	ZYRO0A00132g	some similarities with SACE YKL219W COS9
		ZYRO0A00198g	some similarities with  SACE YJR161C COS5
		ZYRO0A00242g	some similarities with SACE YHL044W Putative integral membrane protein, member of DUP240 gene family
		ZYRO0A11198g	no similarity
		ZYRO0A11242g	no similarity
		ZYRO0A11286g	no similarity
		ZYRO0A11308g	no similarity
		ZYRO0A11352g	no similarity
		ZYRO0A13860g	no similarity
		ZYRO0A13926g	no similarity
		ZYRO0B00110g	no similarity
		ZYRO0B17006g	weakly similar to SACE YGL051W MST27 and YAR033W MST28 Putative integral membrane proteins, involved in vesicle formation; member of DUP240 gene family
		ZYRO0C00198g	some similarities with SACE YKL219W COS9
		ZYRO0D00176g	no similarity
		ZYRO0D00220g	no similarity
		ZYRO0D00264g	no similarity
		ZYRO0E00286g	no similarity
		ZYRO0F05368g	no similarity
		ZYRO0F05412g	some similarities with SACE YHL048W COS8
Ê	Ê	ZYRO0G00132g	some similarities with SACE YKL219W COS9
			
K. thermotolerans
2	GL3C4023	KLTH0F00110g	conserved hypothetical protein
Ê	Ê	KLTH0F19954g	conserved hypothetical protein
2	GL3C4283	KLTH0B05060g	conserved hypothetical protein
Ê	Ê	KLTH0E14938g	conserved hypothetical protein
2	GL3R3968	KLTH0B10164g	conserved hypothetical protein
Ê	Ê	KLTH0E00286g	conserved hypothetical protein
2	GL3R3973	KLTH0A00462g	some similarities with SACE YDR400W URH1 uridine nucleosidase (uridine ribohydrolase)
Ê	Ê	KLTH0E00154g	conserved hypothetical protein
2	GL3R4294	KLTH0F00132g	conserved hypothetical protein
Ê	Ê	KLTH0F19932g	conserved hypothetical protein
4	GL3R3887	KLTH0C07700g	conserved hypothetical protein
		KLTH0C07722g	conserved hypothetical protein
		KLTH0F12276g	conserved hypothetical protein
Ê	Ê	KLTH0H12914g	conserved hypothetical protein
5	GL3C0059	KLTH0B10318g	no similarity
		KLTH0B10428g	no similarity
		KLTH0D00132g	no similarity
		KLTH0G00132g	no similarity
Ê	Ê	KLTH0G00396g	conserved hypothetical protein
5	GL3R3664	KLTH0A07810g	highly similar to SACE YJL213W
		KLTH0B00264g	highly similar to SACE YJL213W
		KLTH0C11968g	highly similar to SACE YJL213W
		KLTH0E16874g	highly similar to SACE YJL213W
Ê	Ê	KLTH0H00132g	highly similar to SACE YJL213W
			
S. kluyveri
2	GL3C3704	SAKL0E01848g	no similarity
Ê	Ê	SAKL0H17578g	no similarity
2	GL3R4319	SAKL0F09944g	no similarity
Ê	Ê	SAKL0H01408g	no similarity
3	GL3C0410	SAKL0E05324g	weakly similar to Candida glabrata CAGL0B02926g
		SAKL0E05346g	weakly similar to Candida glabrata CAGL0B02926g
Ê	Ê	SAKL0H24090g	weakly similar to Candida glabrata CAGL0D00286g
3	GL3C4061	SAKL0A10582g	conserved hypothetical protein
		SAKL0A10648g	some similarities with SACE YPR015C 
Ê	Ê	SAKL0D15136g	some similarities with SACE YPR015C
3	GL3R4027 (1)	SAKL0B00110g	no similarity
		SAKL0C14080g	no similarity
Ê	Ê	SAKL0E00110g	some similarities with Xylella fastidiosa XF_0626 
4	GL3C3889	SAKL0C03872g	no similarity
		SAKL0C03916g	no similarity
		SAKL0C10648g	weakly similar to SACE YPR065W Heme-dependent repressor of hypoxic genes
Ê	Ê	SAKL0D09922g	conserved hypothetical protein
6	GL3R3665 (1)	SAKL0B01782g	similar to Yellowstone A-Prime CYA_2439 ISSoc2 resolvase
		SAKL0B05940g	similar to  Caldicellulosiruptor saccharolyticus DSM 8903 CsacDRAFT_1700 Regulatory protein MerR
		SAKL0G04686g	similar to Caldicellulosiruptor saccharolyticus DSM 8903 CsacDRAFT_1700 Regulatory protein MerR
		SAKL0H03674g	weakly similar to Yellowstone A- Prime CYA_2425 ISSoc2 resolvase
		SAKL0H06314g	similar to Yellowstone A-Prime CYA_2425 ISSoc2 resolvase
Ê	Ê	SAKL0H06600g	similar to Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime) ISSoc2 resolvase
			
K. lactis
2	GL3C4579	KLLA0A11957g	conserved hypothetical protein
Ê	Ê	KLLA0C19063g	conserved hypothetical protein
2	GL3R4112	KLLA0D06193g	conserved hypothetical protein
Ê	Ê	KLLA0E04599g	no similarity
3	GL3C3955	KLLA0B14531g	conserved hypothetical protein
		KLLA0C00330g	conserved hypothetical protein
Ê	Ê	KLLA0C03113g	Kluyveromyces lactis KLLA0C03113g Sla2 protein
3	GL3R4104	KLLA0A12001g	no similarity
		KLLA0B00220g	conserved hypothetical protein
Ê	Ê	KLLA0D00209g	conserved hypothetical protein
7	GL3C3543	KLLA0A00143g	conserved hypothetical protein
		KLLA0B00166g	conserved hypothetical protein
		KLLA0C00154g	conserved hypothetical protein
		KLLA0D00157g	conserved hypothetical protein
		KLLA0D19987g	conserved hypothetical protein
		KLLA0E00155g	no similarity
Ê	Ê	KLLA0F00176g	no similarity
7	GL3R3212	KLLA0A00154g	conserved hypothetical protein
		KLLA0B00187g	conserved hypothetical protein
		KLLA0C00176g	no similarity
		KLLA0D00187g	no similarity
		KLLA0D19965g	conserved hypothetical protein
		KLLA0E00177g	no similarity
Ê	Ê	KLLA0F00220g	no similarity
			
A. gossypii
2	GL3C4268	ERGO0D00110g	no similarity
Ê	Ê	ERGO0G00132g	no similarity
3	GL3R3997	ERGO0D00308g	no similarity
		ERGO0E18722g	no similarity
Ê	Ê	ERGO0F20900g	no similarity

	The table indicates the series of dispersed paralogs specific to one of the protoploid yeasts with no clearcut homolog in the other species. (1) putative cases of lateral gene transfers that will be published elsewhere (Rolland et al. submitted). 



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