Supplementary Table 11: Conservation series of dispersed paralogs

Species-specific family expansions

 

 

Protein family

ZYRO

KLTH

SAKL

KLLA

ERGO

CDS

Brief description

 

 

 

 

 

 

 

 

Z. rouxii

GL3C0055

10

4

3

2

0

ZYRO0A13574g

similar to SACE YGL039W and YGL157W

 

 

 

 

 

 

ZYRO0B00330g

similar to SACE YGL039W and YGL157W

 

 

 

 

 

 

ZYRO0B16742g

similar to SACE YGL039W and YGL157W

 

 

 

 

 

 

ZYRO0C18546g

similar to SACE YGL039W and YGL157W

 

 

 

 

 

 

ZYRO0E10362g

similar to SACE YGL039W and YGL157W

 

 

 

 

 

 

ZYRO0F05214g

similar to SACE YOL151W GRE2 NADPH-dependent methylglyoxal reductase (D- lactaldehyde dehydrogenase)

 

 

 

 

 

 

ZYRO0F18656g

similar to SACE YOL151W GRE2 NADPH-dependent methylglyoxal reductase (D- lactaldehyde dehydrogenase)

 

 

 

 

 

 

ZYRO0G00242g

similar to SACE YGL039W and YGL157W

 

 

 

 

 

 

ZYRO0G15400g

similar to SACE YOL151W GRE2 NADPH-dependent methylglyoxal reductase (D- lactaldehyde dehydrogenase)

 

 

 

 

 

 

ZYRO0G22506g

similar to SACE YGL039W and YGL157W

GL3C0080

6

3

2

1

1

ZYRO0C11902g

similar to SACE YHR179W OYE2 Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN)

 

 

 

 

 

 

ZYRO0C11924g

similar to SACE YHR179W OYE2 Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN)

 

 

 

 

 

 

ZYRO0F12144g

similar to SACE YHR179W OYE2 Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN)

 

 

 

 

 

 

ZYRO0F13618g

similar to SACE YHR179W OYE2 Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN)

 

 

 

 

 

 

ZYRO0F16852g

similar to SACE YHR179W OYE2 Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN)

 

 

 

 

 

 

ZYRO0G15444g

similar to SACE YHR179W OYE2 Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN)

GL3C0186

6

1

0

0

0

ZYRO0A01122g

similar to SACE YOR388C FDH1 NAD( )-dependent formate dehydrogenase

 

 

 

 

 

 

ZYRO0A08206g

similar to SACE YOR388C FDH1 NAD( )-dependent formate dehydrogenase

 

 

 

 

 

 

ZYRO0D10780g

similar to SACE YOR388C FDH1 NAD( )-dependent formate dehydrogenase

 

 

 

 

 

 

ZYRO0F16874g

similar to SACE YNL274C Putative hydroxyisocaproate dehydrogenase

 

 

 

 

 

 

ZYRO0G18876g

similar to SACE YOR388C FDH1 NAD( )-dependent formate dehydrogenase

 

 

 

 

 

 

ZYRO0G19866g

similar to SACE YOR388C FDH1 NAD( )-dependent formate dehydrogenase

GL3R0232

5

2

2

2

1

ZYRO0B16764g

similar to SACE YDR256C CTA1 Catalase A breaks down hydrogen peroxide in the peroxisomal matrix

 

 

 

 

 

 

ZYRO0C17820g

similar to SACE YGR088W CTT1 Cytosolic catalase T has a role in protection from oxidative damage by hydrogen peroxide

 

 

 

 

 

 

ZYRO0E10318g

similar to SACE YDR256C CTA1 Catalase A breaks down hydrogen peroxide in the peroxisomal matrix

 

 

 

 

 

 

ZYRO0F08426g

similar to SACE YDR256C CTA1 Catalase A breaks down hydrogen peroxide in the peroxisomal matrix

 

 

 

 

 

 

ZYRO0G22462g

similar to SACE YGR088W CTT1 Cytosolic catalase T has a role in protection from oxidative damage by hydrogen peroxide

GL3C0522

4

1

2

1

0

ZYRO0A00286g

similar to SACE YPL088W Putative aryl alcohol dehydrogenase

 

 

 

 

 

 

ZYRO0D02816g

similar to SACE YPL088W Putative aryl alcohol dehydrogenase

 

 

 

 

 

 

ZYRO0F04840g

similar to SACE YPL088W Putative aryl alcohol dehydrogenase

 

 

 

 

 

 

ZYRO0G20504g

similar to SACE YPL088W Putative aryl alcohol dehydrogenase

 

 

 

 

 

 

 

 

K. thermotolerans

GL3R0092

3

6

3

3

3

KLTH0C01188g

highly similar to SACE YKL085W MDH1 Mitochondrial malate dehydrogenase

 

 

 

 

 

 

KLTH0D00440g

conserved hypothetical protein

 

 

 

 

 

 

KLTH0E09614g

similar to SACE YDL078C MDH3 Cytoplasmic malate dehydrogenase

 

 

 

 

 

 

KLTH0F18854g

similar to SACE YOL126C MDH2 Cytoplasmic malate dehydrogenase

 

 

 

 

 

 

KLTH0G19536g

similar to SACE YDL078C MDH3 Cytoplasmic malate dehydrogenase

 

 

 

 

 

 

KLTH0G19558g

similar to SACE YDL078C MDH3 Cytoplasmic malate dehydrogenase

 

 

 

 

 

 

 

 

S. kluyveri

GL3M4590

4

6

12

5

3

SAKL0A00572g

some similarities withSACE YCR089W FIG2 Cell wall adhesin expressed specifically during mating

 

 

 

 

 

 

SAKL0A02200g

some similarities with SACE YHR211W  FLO5 and YAR050W FLO1 Lectin-like proteins involved in flocculation

 

 

 

 

 

 

SAKL0C09130g

some similarities with SACE YHR211W  FLO5 and YAR050W FLO1 Lectin-like proteins involved in flocculation

 

 

 

 

 

 

SAKL0D09944g

some similarities with SACE YIR019C MUC1 GPI-anchored cell surface glycoprotein

 

 

 

 

 

 

SAKL0E00528g

some similarities with SACE YHR211W  FLO5 and YAR050W FLO1 Lectin-like proteins involved in flocculation

 

 

 

 

 

 

SAKL0E15378g

some similarities with SACE YHR211W  FLO5 and YAR050W FLO1 Lectin-like proteins involved in flocculation

 

 

 

 

 

 

SAKL0G19910g

some similarities with SACE YAL063C

 

 

 

 

 

 

SAKL0H00176g

conserved hypothetical protein

 

 

 

 

 

 

SAKL0H00286g

conserved hypothetical protein

 

 

 

 

 

 

SAKL0H21340g

no similarity

 

 

 

 

 

 

SAKL0H21362g

some similarities with SACE YIR019C MUC1 GPI-anchored cell surface glycoprotein

 

 

 

 

 

 

SAKL0H23188g

some similarities with SACE YIR019C MUC1 GPI-anchored cell surface glycoprotein

GL3C0107

2

3

6

3

1

SAKL0D02486g

similar to SACE YDR242W AMD2 Putative amidase

 

 

 

 

 

 

SAKL0E04994g

conserved hypothetical protein

 

 

 

 

 

 

SAKL0E15312g

similar to SACE YDR242W AMD2 Putative amidase

 

 

 

 

 

 

SAKL0H01254g

similar to SACE YMR293C

 

 

 

 

 

 

SAKL0H11990g

similar to SACE YDR242W AMD2 Putative amidase

 

 

 

 

 

 

SAKL0H23804g

similar to SACE YDR242W AMD2 Putative amidase

GL3R0543

1

1

5

1

1

SAKL0B12826g

similar to SACE YBR158W AMN1 Involved in daughter cell separation and Chromosome Stability

 

 

 

 

 

 

SAKL0G00110g

similar to SACE YBR158W AMN1 Involved in daughter cell separation and Chromosome Stability

 

 

 

 

 

 

SAKL0G00132g

similar to SACE YBR158W AMN1 Involved in daughter cell separation and Chromosome Stability

 

 

 

 

 

 

SAKL0G19866g

similar to SACE YBR158W AMN1 Involved in daughter cell separation and Chromosome Stability

 

 

 

 

 

 

SAKL0H10824g

similar to SACE YBR158W AMN1 Involved in daughter cell separation and Chromosome Stability

GL3C0086

1

1

4

2

1

SAKL0C03102g

conserved hypothetical protein

 

 

 

 

 

 

SAKL0C03124g

conserved hypothetical protein

 

 

 

 

 

 

SAKL0G04004g

similar to SACE YDR402C DIT2 Sporulation-specific enzyme required for spore wall maturation involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall

 

 

 

 

 

 

SAKL0H11176g

conserved hypothetical protein

 

 

 

 

 

 

 

 

K. lactis

GL3C0074

1

4

4

12

0

KLLA0A00132g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0B00143g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0C00132g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0C06677g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0C17336g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0D00143g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0D10131g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0D20009g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0E00133g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0F00154g

similar to SACE YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases

 

 

 

 

 

 

KLLA0F11077g

weakly similar to SACE YNL125C ESBP6 Protein with similarity to monocarboxylate permeases

 

 

 

 

 

 

KLLA0F24200g

weakly similar to SACE YNL125C ESBP6 Protein with similarity to monocarboxylate permeases

GL3C0221

2

2

2

7

0

KLLA0A00110g

conserved hypothetical protein

 

 

 

 

 

 

KLLA0C00110g

conserved hypothetical protein

 

 

 

 

 

 

KLLA0C06699g

conserved hypothetical protein

 

 

 

 

 

 

KLLA0D13002g

conserved hypothetical protein

 

 

 

 

 

 

KLLA0D20031g

conserved hypothetical protein

 

 

 

 

 

 

KLLA0E00111g

conserved hypothetical protein

 

 

 

 

 

 

KLLA0F00132g

conserved hypothetical protein

GL3C3528

0

2

0

5

0

KLLA0B00308g

some similarities with SACE YAR050W

 

 

 

 

 

 

KLLA0B14916g

some similarities with SACE YHR211W FLO5 Lectin-like protein involved in flocculation

 

 

 

 

 

 

KLLA0C19316g

some similarities with SACE YAL063C

 

 

 

 

 

 

KLLA0D00275g

some similarities with SACE YAL063C

 

 

 

 

 

 

KLLA0E25147g

some similarities with SACE YAL063C

GL3R0383

0

2

2

5

0

KLLA0A00176g

similar to SACE YBR092C PHO3 Constitutively expressed acid phosphatase

 

 

 

 

 

 

KLLA0B00286g

similar to SACE YBR092C PHO3 Constitutively expressed acid phosphatase

 

 

 

 

 

 

KLLA0C19338g

similar to SACE YBR092C PHO3 Constitutively expressed acid phosphatase

 

 

 

 

 

 

KLLA0D00258g

similar to SACE YBR092C PHO3 Constitutively expressed acid phosphatase

 

 

 

 

 

 

KLLA0E24949g

similar to SACE YBR092C PHO3 Constitutively expressed acid phosphatase

 

 

 

 

 

 

 

 

A. gossypii

GL3M4603

0

0

1

2

6

ERGO0D08272g

Syntenic homolog of SACE YPR015C

 

 

 

 

 

 

ERGO0D08316g

Syntenic homolog of SACE YPR013C

 

 

 

 

 

 

ERGO0D16368g

no similarity

 

 

 

 

 

 

ERGO0E06490g

no similarity

 

 

 

 

 

 

ERGO0G03696g

no similarity

 

 

 

 

 

 

ERGO0G12518g

no similarity

GL3R0084

1

1

2

1

5

ERGO0B08954g

Syntenic homolog of SACE YJR107W

 

 

 

 

 

 

ERGO0C02222g

Non-syntenic homolog of SACE YJR107W

 

 

 

 

 

 

ERGO0E18656g

Non-syntenic homolog of SACE YJR107W; Tandem gene triplication in this genome'

 

 

 

 

 

 

ERGO0E18678g

Non-syntenic homolog of SACE YJR107W; Tandem gene triplication in this genome'

 

 

 

 

 

 

ERGO0E18700g

Non-syntenic homolog of SACE YJR107W; Tandem gene triplication in this genome'

 

                  The table indicates, for each yeast species, all series of dispersed paralogs of four members of more, that are at least twice more numerous than paralogs of the same family in  other species. Number of genes per species are indicated in columns 2 to 6. Expansions are shadowed, and the corresponding genes are listed in column 7 with their brief description  in column 8.