Family		GL3C0449, 19 members
Phyletic pattern		sczltkgdpy
Phylogen. profile		2 2 2 2 2 2 2 2 2 1
Proteins		YALI0F30261p PISO0J15475p PISO0I13670p DEHA2G08800p DEHA2F05676p ERGO0F10890p ERGO0A08074p KLLA0F17479p KLLA0C05368p KLTH0H06952p KLTH0E09174p SAKL0E04488p SAKL0A07546p ZYRO0D15026p ZYRO0A08932p CAGL0G09493p CAGL0A03432p SACE0O08074p SACE0L02200p

Family relations  

Proteins in GL3C0449  

YALI0F30261p	some similarities with uniprot|O60177 Schizosaccharomyces pombe DEAD box helicase; SubName: Full=YALI0F30261p;
PISO0J15475p	weakly similar to uniprot|Q08562 Saccharomyces cerevisiae SACE0O08074g RIS1_YEAST DIS1 RIS1 TID4 ULS1 YOR191W RING finger protein involved in proteolytic control of sumoylated substrates;
PISO0I13670p	weakly similar to uniprot|Q08562 Saccharomyces cerevisiae SACE0O08074g RIS1_YEAST DIS1 RIS1 TID4 ULS1 YOR191W RING finger protein involved in proteolytic control of sumoylated substrates;
DEHA2G08800p	similar to uniprot|P32849 Saccharomyces cerevisiae YLR032W RAD5 Single-stranded DNA-dependent ATPase; RecName: Full=DNA repair protein RAD5; EC=3.6.4.-;
DEHA2F05676p	some similarities with uniprot|Q08562 Saccharomyces cerevisiae YOR191W RIS1 Member of the SWI/SNF family of DNA-dependent ATPases plays a role in antagonizing silencing during mating-type switching contains an N- terminal domain that interacts with Sir4p and a C-terminal SNF2 domain and similar to CA4382|IPF8576 Candida albicans IPF8576; SubName: Full=DEHA2F05676p;
ERGO0F10890p	AGOS_AFR220W, Syntenic homolog of Saccharomyces cerevisiae YLR032W (RAD5)
ERGO0A08074p	AGOS_AAR147W, Syntenic homolog of Saccharomyces cerevisiae YOR191W (RIS1)
KLLA0F17479p	similar to uniprot|P32849 Saccharomyces cerevisiae YLR032W RAD5 Single-stranded DNA-dependent ATPase involved in postreplication repair; RecName: Full=DNA repair protein RAD5; EC=3.6.4.-;
KLLA0C05368p	some similarities with uniprot|Q08562 Saccharomyces cerevisiae YOR191W RIS1 Member of the SWI/SNF family of DNA-dependent ATPases plays a role in antagonizing silencing during mating-type switching contains an N- terminal domain that interacts with Sir4p and a C-terminal SNF2 domain; SubName: Full=KLLA0C05368p;
KLTH0H06952p	weakly similar to uniprot|Q08562 Saccharomyces cerevisiae YOR191W RIS1 Member of the SWI/SNF family of DNA-dependent ATPases plays a role in antagonizing silencing during mating-type switching contains an N- terminal domain that interacts with Sir4p and a C-terminal SNF2 domain; SubName: Full=KLTH0H06952p;
KLTH0E09174p	similar to uniprot|P32849 Saccharomyces cerevisiae YLR032W RAD5 Single-stranded DNA-dependent ATPase involved in postreplication repair contains RING finger domain; SubName: Full=KLTH0E09174p;
SAKL0E04488p	similar to uniprot|P32849 Saccharomyces cerevisiae YLR032W RAD5 DNA helicase proposed to promote replication fork regression during postreplication repair by template switching;
SAKL0A07546p	weakly similar to uniprot|Q08562 Saccharomyces cerevisiae YOR191W ULS1 RING finger protein involved in proteolytic control of sumoylated substrates;
ZYRO0D15026p	similar to uniprot|Q08562 Saccharomyces cerevisiae YOR191W RIS1 Member of the SWI/SNF family of DNA-dependent ATPases plays a role in antagonizing silencing during mating-type switching contains an N-terminal domain that interacts with Sir4p and a C-terminal SNF2 domain; SubName: Full=ZYRO0D15026p;
ZYRO0A08932p	similar to uniprot|P32849 Saccharomyces cerevisiae YLR032W RAD5 Single-stranded DNA-dependent ATPase involved in postreplication repair contains RING finger domain; SubName: Full=ZYRO0A08932p;
CAGL0G09493p	similar to uniprot|Q08562 Saccharomyces cerevisiae YOR191w RIS1; SubName: Full=Similar to uniprot|Q08562 Saccharomyces cerevisiae YOR191w RIS1;
CAGL0A03432p	similar to uniprot|P32849 Saccharomyces cerevisiae YLR032w RAD5; RecName: Full=DNA repair protein RAD5; EC=3.6.4.-;
SACE0O08074p	YOR191W ULS1, RING finger protein involved in proteolytic control of sumoylated substrates; interacts with SUMO (Smt3p); member of the SWI/SNF family of DNA- dependent ATPases; plays a role in antagonizing silencing during mating-type switching
SACE0L02200p	YLR032W RAD5, DNA helicase proposed to promote replication fork regression during postreplication repair by template switching; RING finger containing ubiquitin ligase; stimulates the synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p

Gene Ontology terms  

None available yet

Data  

Pairwise distances

Amino-acid sequences

Multiple sequence alignment

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Legend and notes  

Type of family, see Definitions for more information.

GL3R*	Robust families
GL3C*	Consensus families
GL3M*	Multiple choice families (resolved arbitrarily in favor of smaller groups)
GL3U*	Unique element families (singletons)

Phyletic pattern
This pattern is an ordered chain of letters indicating which species are involved in the family. A letter indicates that the species is present, a dash in place of the letter shows that the species is absent.

Letter	Species
s	Saccharomyces cerevisiae
c	Candida glabrata
z	Zygosaccharomyces rouxii
l	Saccharomyces kluyveri
t	Kluyveromyces thermotolerans
k	Kluyveromyces lactis var. lactis
g	Eremothecium gossypii
d	Debaryomyces hansenii var. hansenii
y	Yarrowia lipolytica

Phylogenetic profile
This profile is an ordered chain of numbers indicating how many proteins of each species are present in the family. The order of the numbers is the same as the order in the phyletic pattern (see above).

Family relations
Click on a node of the image to go to the page of the corresponding gene. The weight of an edge between two genes is the percent amino-acid identity in a Needleman Wunch global alignment between the translation products of the two genes. The graph shown is the subgraph induces by edges with weight ≥ 20%.

Data
Colored multiple sequence alignments are computed using TCoffee.