YALI0A09636p_blastp.html 
BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= YALI0A09636p (infer) YLR285w NNT1 nicotinamide
N-methyltransferase : similar to uniprot|Q05874 Saccharomyces
cerevisiae [Yarrowia lipolytica CLIB122]
         (273 letters)

Database: Genolevures3.aa 
           48,939 sequences; 23,992,848 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

|YALI0A09636p (infer) YLR285w NNT1 nicotinamide N-methyltransfera...   559   e-159
|SAKL0A07986p (infer) YLR285W NNT1 Putative nicotinamide N- methy...   241   6e-64
|KLTH0G15092p (infer) YLR285W NNT1 Putative nicotinamide N- methy...   234   7e-62
|SACE0L13925p Putative nicotinamide N-methyltransferase, has a ro...   231   7e-61
|CAGL0M09801p (infer) YLR285w : similar to uniprot|Q05874 Sacchar...   225   4e-59
|ZYRO0D14542p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   225   5e-59
|KLLA0C04708p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   224   7e-59
|DEHA2F21604p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   221   5e-58
|ERGO0G14674p Syntenic homolog of Saccharomyces cerevisiae YLR285...   215   5e-56


>|YALI0A09636p (infer) YLR285w NNT1 nicotinamide N-methyltransferase : similar to
           uniprot|Q05874 Saccharomyces cerevisiae [Yarrowia
           lipolytica CLIB122]
          Length = 273

 Score =  559 bits (1441), Expect = e-159,   Method: Compositional matrix adjust.
 Identities = 273/273 (100%), Positives = 273/273 (100%)

Query: 1   MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW 60
           MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW
Sbjct: 1   MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW 60

Query: 61  GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL 120
           GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL
Sbjct: 61  GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL 120

Query: 121 LYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELIEMSGGTGYDLV 180
           LYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELIEMSGGTGYDLV
Sbjct: 121 LYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELIEMSGGTGYDLV 180

Query: 181 ILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGFESE 240
           ILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGFESE
Sbjct: 181 ILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGFESE 240

Query: 241 KLFELKYYPMFEEEEETKELRSMVFGYMLTLKE 273
           KLFELKYYPMFEEEEETKELRSMVFGYMLTLKE
Sbjct: 241 KLFELKYYPMFEEEEETKELRSMVFGYMLTLKE 273


>|SAKL0A07986p (infer) YLR285W NNT1 Putative nicotinamide N- methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           highly similar to uniprot|Q05874 Saccharomyces
           cerevisiae [Lachancea kluyveri]
          Length = 270

 Score =  241 bits (615), Expect = 6e-64,   Method: Compositional matrix adjust.
 Identities = 135/279 (48%), Positives = 174/279 (62%), Gaps = 20/279 (7%)

Query: 1   MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW 60
           MSD E L  G LF+EP+DF KP  QP   +Y R    V+           LRL   +PLW
Sbjct: 1   MSDTESLIEGSLFEEPEDFNKPPPQPHFATYERTT--VSPQSNSLVKEVKLRLVGSSPLW 58

Query: 61  GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL 120
           GHLLWNAG  T  +LDE+   LV+ K V+E GA   LPS++C  +GA +VV+TD+PDADL
Sbjct: 59  GHLLWNAGIYTGRHLDENIG-LVKDKTVLELGAAGALPSIICGLIGASKVVVTDFPDADL 117

Query: 121 LYNLKYNVD-------QLKKDWD-AKNADFSGPSPCADVSSMKVEGFIWGNDASELIEMS 172
           L N++YNVD       +L  D D A++ +            + VEG+IWGND   L++  
Sbjct: 118 LQNIQYNVDHQIYQGNELPADGDDARDQELQR-------RDVVVEGYIWGNDYEPLVKHI 170

Query: 173 G-GTGYDLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRA 231
           G G  +DL+ILSD+VFNHSEHAKL+ + K+LLA  GK  VVF+PHR  L N DL FF  A
Sbjct: 171 GSGKKFDLIILSDLVFNHSEHAKLLNTTKDLLAKDGKALVVFSPHRPWLLNADLQFFETA 230

Query: 232 KDEAGFESEKLFELKYYPMFEEEEETKELRSMVFGYMLT 270
           K E G + EK+  + + PMFEE+EET E+RS V+ Y LT
Sbjct: 231 K-EHGLKPEKIEMVNWKPMFEEDEETAEIRSRVYAYYLT 268


>|KLTH0G15092p (infer) YLR285W NNT1 Putative nicotinamide N- methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Kluyveromyces thermotolerans]
          Length = 266

 Score =  234 bits (597), Expect = 7e-62,   Method: Compositional matrix adjust.
 Identities = 126/272 (46%), Positives = 176/272 (64%), Gaps = 10/272 (3%)

Query: 1   MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW 60
           MSD E    G +F EP+ +++ E +     Y R++  V ++   +     LRL   +PLW
Sbjct: 1   MSDTESFIQGDIFAEPEGYFQAEPEAHFAEYVREQ--VPSASKSQKKEVRLRLVGSSPLW 58

Query: 61  GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL 120
           GHLLWNAG  T+++LD+   +LV+ + V+E GA   LPS++   +GAK+ V+TDYPDADL
Sbjct: 59  GHLLWNAGIYTANHLDKFP-DLVKDRCVLELGAAGALPSVVAGMIGAKKCVVTDYPDADL 117

Query: 121 LYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELIEM--SGGTGYD 178
           L N++YNVD    D +A  +D +G S      ++ VEG+IWGND + L+     G T +D
Sbjct: 118 LQNIQYNVDHEVFDGEALPSDGAGASE----RNVVVEGYIWGNDYAPLVSHLPCGTTKFD 173

Query: 179 LVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGFE 238
           LVILSD+VFNH+EH KL+++ K+LLA  GK  VVF+PHR  L N+DL FF  AKD A   
Sbjct: 174 LVILSDLVFNHTEHLKLLQTTKDLLAQDGKALVVFSPHRPWLLNDDLQFFETAKDFA-LV 232

Query: 239 SEKLFELKYYPMFEEEEETKELRSMVFGYMLT 270
            EK+  + + PMFEE+EET E+RS V+ Y LT
Sbjct: 233 PEKIEMVNWKPMFEEDEETSEIRSRVYAYYLT 264


>|SACE0L13925p Putative nicotinamide N-methyltransferase, has a role in rDNA
           silencing and in lifespan determination [Saccharomyces
           cerevisiae]
          Length = 261

 Score =  231 bits (589), Expect = 7e-61,   Method: Compositional matrix adjust.
 Identities = 124/276 (44%), Positives = 170/276 (61%), Gaps = 24/276 (8%)

Query: 1   MSDIEDLA-SGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPL 59
           MSDIE L  + GLF+EP+DF  P  +P    Y R   H+      +  +  LRL   +PL
Sbjct: 1   MSDIESLGEAAGLFEEPEDFLPPPPKPHFAEYQRS--HITKESKSDVKDIKLRLVGTSPL 58

Query: 60  WGHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDAD 119
           WGHLLWNAG  T+++LD H  EL++GK V+E GA A LPS++C   GA+ VV TDYPD D
Sbjct: 59  WGHLLWNAGIYTANHLDSHP-ELIKGKTVLELGAAAALPSVICALNGAQMVVSTDYPDPD 117

Query: 120 LLYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASEL---IEMSGGTG 176
           L+ N+ YN+                 +   D +++  EG+IWGND S L   IE  G   
Sbjct: 118 LMQNIDYNIKS---------------NVPEDFNNVSTEGYIWGNDYSPLLAHIEKIGNNN 162

Query: 177 --YDLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDE 234
             +DL+ILSD+VFNH+EH KL+++ K+LLA  G+  VVF+PHR KL  +DL+FF  AK+E
Sbjct: 163 GKFDLIILSDLVFNHTEHHKLLQTTKDLLAEKGQALVVFSPHRPKLLEKDLEFFELAKNE 222

Query: 235 AGFESEKLFELKYYPMFEEEEETKELRSMVFGYMLT 270
                + +  + + PMF+E+EET E+RS V+ Y LT
Sbjct: 223 FHLVPQLIEMVNWKPMFDEDEETIEVRSRVYAYYLT 258


>|CAGL0M09801p (infer) YLR285w : similar to uniprot|Q05874 Saccharomyces
           cerevisiae [Candida glabrata CBS 138]
          Length = 256

 Score =  225 bits (574), Expect = 4e-59,   Method: Compositional matrix adjust.
 Identities = 126/273 (46%), Positives = 172/273 (63%), Gaps = 22/273 (8%)

Query: 1   MSDIEDLASG-GLFDEPKDFYKPEEQPGSDSYARQEK-HVAASEYKEPTNFNLRLTAKNP 58
           MSD E L    GLFDEP+DF +PE+    + YA  E+  V      + TN  L+L   +P
Sbjct: 1   MSDTESLNDALGLFDEPEDF-RPEKP--KEHYANYERIDVPDISKSKITNLKLQLVGSSP 57

Query: 59  LWGHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDA 118
           LWGHLLWNAG  T+ +LD++  ELV  K V+E GA + LPSL+   +GAK+ V+TDYPDA
Sbjct: 58  LWGHLLWNAGIYTARHLDKYP-ELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDA 116

Query: 119 DLLYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASEL-IEMSGGTGY 177
           DL+ N++YNV+ +  D   +N              ++VEG+IWGN+   L I + G   +
Sbjct: 117 DLMANIQYNVNTIIPDELKEN--------------VRVEGYIWGNEYDPLTIHLDGDKKF 162

Query: 178 DLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGF 237
           DL+ILSD+VFNH++H KL+++ K+LLA  GK  VVF+PHR  L   DL FF   K E G 
Sbjct: 163 DLIILSDLVFNHNQHDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCK-EYGL 221

Query: 238 ESEKLFELKYYPMFEEEEETKELRSMVFGYMLT 270
             EK+  + + PMFEE+EET E+RS V+ Y +T
Sbjct: 222 TPEKIEMVNWKPMFEEDEETAEVRSRVYAYYMT 254


>|ZYRO0D14542p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Zygosaccharomyces rouxii]
          Length = 263

 Score =  225 bits (573), Expect = 5e-59,   Method: Compositional matrix adjust.
 Identities = 120/273 (43%), Positives = 171/273 (62%), Gaps = 17/273 (6%)

Query: 1   MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW 60
           MSD E   + G+F+EP DF  P  +     Y R+  +V+     +     LRL  K+PLW
Sbjct: 1   MSDNELDGAFGVFEEPTDFLPPPPEAHFADYERE--YVSKESDSQNKKVQLRLVGKSPLW 58

Query: 61  GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL 120
           GH+LWNAG  T+ +LD+H   LV+GK V+E GA A LP+++C  +GA +VV TDYP+ +L
Sbjct: 59  GHMLWNAGIYTAKHLDKHPG-LVKGKNVLELGAAAALPTVVCGLIGANKVVSTDYPEPEL 117

Query: 121 LYNLKYNVDQLKKDWDAKNADFSGPSPCADVSS---MKVEGFIWGNDASELIEMSGGTGY 177
           + N++YNVD           +  G  P +  S+   + VEG+IWGN+   ++  +GG+ +
Sbjct: 118 IQNIQYNVDH----------ELYGGKPFSQDSNDRKVVVEGYIWGNEYEPILSHTGGSKF 167

Query: 178 DLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGF 237
           DL+ILSD VFNH+EH KL+R  K+LLA  GK  VVF+PHR +L + DL FF  AK E G 
Sbjct: 168 DLIILSDCVFNHTEHRKLLRCIKDLLANDGKALVVFSPHRPRLLDVDLSFFETAK-EFGL 226

Query: 238 ESEKLFELKYYPMFEEEEETKELRSMVFGYMLT 270
             E +  +K++PMF+E+  T E+RS V+ Y LT
Sbjct: 227 APEFIDLVKWHPMFDEDPSTAEIRSRVYAYYLT 259


>|KLLA0C04708p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Kluyveromyces lactis NRRL Y-1140]
          Length = 270

 Score =  224 bits (572), Expect = 7e-59,   Method: Compositional matrix adjust.
 Identities = 124/280 (44%), Positives = 175/280 (62%), Gaps = 22/280 (7%)

Query: 1   MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW 60
           MSDIE L  G LF EP DFYKP  +P   +Y R +  V  S   +  +  LRL   +PLW
Sbjct: 1   MSDIESLNGGDLFAEPSDFYKPPPEPHFATYTRDD--VPESSTSQQKDIKLRLVGSSPLW 58

Query: 61  GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL 120
           GHLLWNAG  T+ ++D H +E V+ K V+E GA   LP+++   +GA++VV TDYPDADL
Sbjct: 59  GHLLWNAGIYTAKHMDSHPEE-VQDKLVLELGAAGALPTIIAGLLGARKVVSTDYPDADL 117

Query: 121 LYNLKYNVD-------QLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELIEM-- 171
           + N++YNVD       +L KD + ++   +          + VEG+IWGND   +++   
Sbjct: 118 ISNIQYNVDHNIYGGEELFKDEEKRSKQMAN-------RKVVVEGYIWGNDYEPILKHLP 170

Query: 172 SGGTGYDLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRA 231
                +DL+ILSD+VFNH+EHAKL ++ K+LL   GK  VVF+PHR  L   DL FF+  
Sbjct: 171 QDQQKFDLIILSDLVFNHTEHAKLFKTTKDLLRENGKALVVFSPHRPWLLENDLAFFKDC 230

Query: 232 KDEAGFESEKLFELKYY-PMFEEEEETKELRSMVFGYMLT 270
            +E G +S+ L EL ++ PMF+E+EET E+RS ++ Y L+
Sbjct: 231 -EEFGLKSD-LIELTHWKPMFDEDEETVEIRSSIYAYYLS 268


>|DEHA2F21604p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Debaryomyces hansenii CBS767]
          Length = 254

 Score =  221 bits (564), Expect = 5e-58,   Method: Compositional matrix adjust.
 Identities = 120/275 (43%), Positives = 166/275 (60%), Gaps = 29/275 (10%)

Query: 1   MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW 60
           MSD ++    GLF EP+ F  P   P    Y R+ K        +P   NLRL  K+PLW
Sbjct: 1   MSD-DEFIDTGLFAEPEGFTPPPPPPHFAKYQRKNK-------TDPAELNLRLVGKSPLW 52

Query: 61  GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL 120
           GHLLWNAG  T+DYLD+H+ ELV GK V+E GA AGLPSL+C      +VV TDYPD DL
Sbjct: 53  GHLLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDL 112

Query: 121 LYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELI-----EMSGGT 175
           + N+++N D  +                 D+S   V+GFIWG DA  L+     E+    
Sbjct: 113 ISNIQHNFDHCQG---------------LDLSKTVVKGFIWGADAKPLMDDSEKEIQNED 157

Query: 176 GYDLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEA 235
            +DLVILSD+VFNH+EH KL+++ ++ +   GK  VVF+PHR KL   DL+FFR  +D  
Sbjct: 158 KFDLVILSDLVFNHTEHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCED-F 216

Query: 236 GFESEKLFELKYYPMFEEEEETKELRSMVFGYMLT 270
            F++EK+  + + PMFEE++E+ ++R+ V+ + L 
Sbjct: 217 QFKAEKIDLVTWKPMFEEDDESIDIRARVYSFFLV 251


>|ERGO0G14674p Syntenic homolog of Saccharomyces cerevisiae YLR285W (NNT1)
           [Eremothecium gossypii]
          Length = 265

 Score =  215 bits (547), Expect = 5e-56,   Method: Compositional matrix adjust.
 Identities = 113/262 (43%), Positives = 159/262 (60%), Gaps = 18/262 (6%)

Query: 12  LFDEPKDFYKPEEQPGSDSYARQEKH-VAASEYKEPTNFNLRLTAKNPLWGHLLWNAGKV 70
           LF EP  FY   E+P    +A  E+  V A   +  T   +RL   +PLWGHLLWN+   
Sbjct: 16  LFGEPDGFY---EKPAESHFAEYERSAVPAQSARRDTQVRIRLVGSSPLWGHLLWNSAIY 72

Query: 71  TSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADLLYNLKYNVDQ 130
           T+ +LD H +++V G+ V+E GA   LPSL+   +GA+QVV TDYPDADL+ N++YNVD 
Sbjct: 73  TARHLDAHPEQVV-GRCVLELGAAGALPSLVAGLLGARQVVATDYPDADLVGNIQYNVDH 131

Query: 131 LKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELIEM--SGGTGYDLVILSDVVFN 188
           +            G  P  +   + VEG+IWGND   L      G TG+DLV+LSD+VFN
Sbjct: 132 V----------IYGGKPPTEAPHVAVEGYIWGNDYGPLRRHLPPGQTGFDLVLLSDLVFN 181

Query: 189 HSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGFESEKLFELKYY 248
           H+EH KL+++ ++LLAP G+  VVF+PHR  L  +DL FF  A  E G  +E + ++ + 
Sbjct: 182 HTEHHKLLQTTRDLLAPAGRALVVFSPHRPWLLEKDLQFFETAA-EYGLRAELIEQVTWA 240

Query: 249 PMFEEEEETKELRSMVFGYMLT 270
           PMF ++    E+R+ V+ Y LT
Sbjct: 241 PMFADDPGPAEVRARVYAYYLT 262



BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.