SACE0D06688g

Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine

Genomic environment map

Element type: CDS
Element length: 1686 nucleotides,
on sense strand of
Sace0D: 576471..578156.
Other names:
LCB2
SCS1
TSC1
YDR062W
Coding sequence: 562 codons.

Database cross references:
ArrayExpress: P40970
CYGD: YDR062w
EMBL: AAA34740.1
EMBL: AAA53669.1
EMBL: AAU09688.1
EMBL: AY723771
EMBL: CAA58978.1
EMBL: CAA89091.1
EMBL: CAA98880.1
EMBL: L33931
EMBL: M95669
EMBL: X84162
EMBL: Z49209
EMBL: Z74358
Ensembl: YDR062W
GeneID: 851634
GenomeReviews: Z71256_GR
HOGENOM: P40970
NMPDR: fig|4932.3.peg.1092

Computed results

None available yet

Homologs and Orthologs

Génolevures family GL3C0100
Consensus family of 28 members, scrltkgdy (3 3 3 3 3 3 3 3 4)
28-member family, phyletic pattern sczltkgdy, profile (3 3 3 3 3 3 3 3 4)
Proteins: SACE0D06688p SACE0D10252p SACE0M10164p CAGL0B02607p CAGL0G00440p CAGL0G05071p ZYRO0A10032p ZYRO0D07282p ZYRO0G09152p SAKL0H01144p SAKL0H12364p SAKL0H19272p KLTH0B09306p KLTH0E10538p KLTH0H07920p KLLA0A09955p KLLA0C15059p KLLA0D02134p ERGO0B02486p ERGO0B08624p ERGO0G11220p DEHA2B05478p DEHA2E02134p DEHA2F24926p YALI0C03179p YALI0C06083p YALI0E17545p YALI0F15345p
Search in: Génolevures Google

Génolevures family GL3C0100.N1
Nine-SONS subgroup of a Consensus family
8-member family, phyletic pattern sczltk-dy, profile (1 1 1 1 1 1 0 1 1)
Proteins: SACE0D06688p CAGL0G05071p ZYRO0G09152p SAKL0H19272p KLTH0H07920p KLLA0D02134p DEHA2F24926p YALI0C06083p
Search in: Génolevures Google

Homologs in protein families: GL3C0100 GL3C0100.N1
Orthologs: strict determination not possible; homologs must be refined manually

Protein SACE0D06688p

Protein domain map

Protein length: 561 amino acids
Protein family: GL3C0100

Database cross references:
DIP: DIP:6658N
Gene3D: G3DSA:3.40.640.10
GermOnline: YDR062W
HSSP: 1FC4
HSSP: P07912
IntAct: P40970
InterPro: IPR001917
InterPro: IPR004839
InterPro: IPR015421
KEGG: sce:YDR062W
LinkHub: P40970
PIR: S54046
PROSITE: PS00599
PeptideAtlas: P40970
Pfam: PF00155
RefSeq: NP_010347.1
SGD: S000002469
UniProtKB/Swiss-Prot: P40970
UniprotKB: LCB2_YEAST

Computed results for SACE0D06688p

Blastp Genolevures

Blastp Uniprot

Gene Ontology terms

GO:0030148	sphingolipid biosynthetic process
GO:0017059	serine C-palmitoyltransferase complex
GO:0005792	microsome
GO:0004758	serine C-palmitoyltransferase activity

Sequence data

>SACE0D06688g.nt
GAATATGTATCTGAAATATTTTGGCCTGGACAAAGACGCCGATAGTGTTTTATTTGAACA
GTTGTCCGTAAGTGACCAGAAACTAGTCCTTTTTGTCAGGTCTTTAATTAAGATGCCGCA
AATATTGATTCTCGATGAGGCATTTTCTGGAATGGAGGTAGAACCTATGATGCGTTGTCA
TGAATTTTTAGAGGAGTGGCCTGGAACAGTCCTTGTAGTGGCACACGTTGCCGAAGAGAC
ACCAAAATGTGCCCATTACTTAAGGCTCATATCTCCTGGAGAGTATGAAATAGGCGATAT
GGAAAATTAAAGTTTTCTGTTGTGTGGCAGCAAGAGACAGAACCTCGATAATTTGACATA
CGTATATAATAGTACATGTACATAAAAAGCTACGCAAATATCGTATATCTGTTATACTAC
AAAACAATTACTTCTATATCATAGCCAGTTAGCGGGAACGACTTCAGCTAAATGGACTAT
CCATGCTTTAGGCAGAGGCGAAGCGCGGTGATTGGGTGTAACATCATCTCCTTTTCTCTA
CGACAAATTCCCAAAAAAAAAATTTATGCTATGTTAATACCTGCACAATTCAACCGTGCT
GAAACGTAAAATTAAGGTGATTATACGGATAGTATACGATATTATCAATCTCATAAGAAA
AATCTCTTTTGAATTTAACGGAGGGATTATTCATTAGAAAGCGTTCTTACCATTCACTAG
GAGCGAATCCGTGGAAGGTGTTTTAACGTTGCCACGAAAAACAGCTCTACATCGAAATAA
AAGACAACAATCAGTGCCCGTAAGTTTCATTACTATTTTCTATTATTATCTGCAACTTTT
TATTAGTTAGGTTTTTTTTGTTTGTTTGTTTGTTTTCAATTGATTAATTTACAAGACAAA
GAACCTTATATTTCGTGTTTTTCATTCTAAAGGAAAAAAAGCATAAAGAAGATTCCACAC
ACTTTATTGTGATAGTTTTCAAAGTAAAAAGTAATAGATTATGAGTACTCCTGCAAACTA
TACCCGTGTGCCCCTGTGCGAACCAGAGGAGCTGCCAGACGACATACAAAAAGAAAATGA
ATATGGTACACTAGATTCTCCGGGGCATTTGTATCAAGTCAAGTCACGTCATGGGAAGCC
ACTACCTGAGCCCGTTGTCGACACCCCTCCTTATTACATTTCTTTGTTAACATATCTAAA
TTATTTGATTCTGATTATATTAGGTCATGTTCACGACTTCTTAGGTATGACCTTCCAAAA
AAACAAACATCTGGATCTTTTAGAGCATGATGGGTTAGCACCTTGGTTTTCAAATTTCGA
GAGTTTTTATGTCAGGAGAATTAAAATGAGAATTGATGATTGCTTTTCTAGACCAACTAC
TGGTGTTCCTGGTAGATTTATTCGTTGTATTGATAGAATTTCTCATAATATAAATGAGTA
TTTTACCTACTCAGGCGCAGTGTATCCATGCATGAACTTATCATCATATAACTATTTAGG
CTTCGCACAAAGTAAGGGTCAATGTACCGATGCCGCCTTGGAATCTGTCGATAAATATTC
TATTCAATCTGGTGGTCCAAGAGCTCAAATCGGTACCACAGATTTGCACATTAAAGCAGA
GAAATTAGTTGCTAGATTTATCGGTAAGGAGGATGCCCTCGTTTTTTCGATGGGTTATGG
TACAAATGCAAACTTGTTCAACGCTTTCCTCGATAAAAAGTGTTTAGTTATCTCTGACGA
ATTGAACCACACCTCTATTAGAACAGGTGTTAGGCTTTCTGGTGCTGCTGTGCGAACTTT
CAAGCATGGTGATATGGTGGGTTTAGAAAAGCTTATCAGAGAACAGATAGTACTTGGTCA
ACCAAAAACAAATCGTCCATGGAAGAAAATTTTAATTTGCGCAGAAGGGTTGTTTTCCAT
GGAAGGTACTTTGTGTAACTTGCCAAAATTGGTTGAATTGAAGAAGAAATATAAATGTTA
CTTGTTTATCGATGAAGCCCATTCTATAGGCGCTATGGGCCCAACTGGTCGCGGTGTTTG
TGAAATATTTGGCGTTGATCCCAAGGACGTCGACATTCTAATGGGTACTTTCACTAAGTC
GTTTGGTGCTGCTGGTGGTTACATTGCTGCTGATCAATGGATTATCGATAGACTGAGGTT
GGATTTAACCACTGTGAGTTATAGTGAGTCAATGCCGGCTCCTGTTTTAGCTCAAACTAT
TTCCTCATTACAAACCATTAGTGGTGAAATATGTCCCGGACAAGGTACTGAAAGATTGCA
ACGTATAGCCTTTAATTCCCGTTATCTACGTTTAGCTTTGCAAAGGTTAGGATTTATTGT
CTACGGTGTGGCTGACTCACCAGTTATTCCCTTACTACTGTATTGTCCCTCAAAGATGCC
CGCATTTTCGAGAATGATGTTACAAAGACGGATTGCTGTTGTTGTTGTTGCTTATCCTGC
TACTCCGCTGATCGAATCAAGAGTAAGATTCTGTATGTCTGCATCTTTAACAAAGGAAGA
TATCGATTATTTACTGCGTCATGTTAGTGAAGTTGGTGACAAATTGAATTTGAAATCAAA
TTCCGGCAAATCCAGTTACGACGGTAAACGTCAAAGATGGGACATCGAGGAAGTTATCAG
GAGAACACCTGAAGATTGTAAGGACGACAAGTATTTTGTTAATTGAATTTTACCTAATTG
CTAGTTAGGTGAAAAATTACAAAATTTCTGGAAGACGTTGGAAACACGCAACGTCTTTTT
TGACATAAACTTAAAACTGCCAAAAGTCAAACAAAAATTGCAAAAAAAGTAAAAAAAGTT
ACGAAAAAAAAAACATTTAAAAGAAAGAAGAAGTTAAAAGTGCACGCAATATGTTCCAGG
ATATGAAATGAAATACCTTTTGTTTCACCTTTTAAATAATTTAATGTTATATATACAACT
TTATCGTATCATATTCGCAATTACATTATACAAGAATGAGTTTTTT

>SACE0D06688g.cds
ATGAGTACTCCTGCAAACTATACCCGTGTGCCCCTGTGCGAACCAGAGGAGCTGCCAGAC
GACATACAAAAAGAAAATGAATATGGTACACTAGATTCTCCGGGGCATTTGTATCAAGTC
AAGTCACGTCATGGGAAGCCACTACCTGAGCCCGTTGTCGACACCCCTCCTTATTACATT
TCTTTGTTAACATATCTAAATTATTTGATTCTGATTATATTAGGTCATGTTCACGACTTC
TTAGGTATGACCTTCCAAAAAAACAAACATCTGGATCTTTTAGAGCATGATGGGTTAGCA
CCTTGGTTTTCAAATTTCGAGAGTTTTTATGTCAGGAGAATTAAAATGAGAATTGATGAT
TGCTTTTCTAGACCAACTACTGGTGTTCCTGGTAGATTTATTCGTTGTATTGATAGAATT
TCTCATAATATAAATGAGTATTTTACCTACTCAGGCGCAGTGTATCCATGCATGAACTTA
TCATCATATAACTATTTAGGCTTCGCACAAAGTAAGGGTCAATGTACCGATGCCGCCTTG
GAATCTGTCGATAAATATTCTATTCAATCTGGTGGTCCAAGAGCTCAAATCGGTACCACA
GATTTGCACATTAAAGCAGAGAAATTAGTTGCTAGATTTATCGGTAAGGAGGATGCCCTC
GTTTTTTCGATGGGTTATGGTACAAATGCAAACTTGTTCAACGCTTTCCTCGATAAAAAG
TGTTTAGTTATCTCTGACGAATTGAACCACACCTCTATTAGAACAGGTGTTAGGCTTTCT
GGTGCTGCTGTGCGAACTTTCAAGCATGGTGATATGGTGGGTTTAGAAAAGCTTATCAGA
GAACAGATAGTACTTGGTCAACCAAAAACAAATCGTCCATGGAAGAAAATTTTAATTTGC
GCAGAAGGGTTGTTTTCCATGGAAGGTACTTTGTGTAACTTGCCAAAATTGGTTGAATTG
AAGAAGAAATATAAATGTTACTTGTTTATCGATGAAGCCCATTCTATAGGCGCTATGGGC
CCAACTGGTCGCGGTGTTTGTGAAATATTTGGCGTTGATCCCAAGGACGTCGACATTCTA
ATGGGTACTTTCACTAAGTCGTTTGGTGCTGCTGGTGGTTACATTGCTGCTGATCAATGG
ATTATCGATAGACTGAGGTTGGATTTAACCACTGTGAGTTATAGTGAGTCAATGCCGGCT
CCTGTTTTAGCTCAAACTATTTCCTCATTACAAACCATTAGTGGTGAAATATGTCCCGGA
CAAGGTACTGAAAGATTGCAACGTATAGCCTTTAATTCCCGTTATCTACGTTTAGCTTTG
CAAAGGTTAGGATTTATTGTCTACGGTGTGGCTGACTCACCAGTTATTCCCTTACTACTG
TATTGTCCCTCAAAGATGCCCGCATTTTCGAGAATGATGTTACAAAGACGGATTGCTGTT
GTTGTTGTTGCTTATCCTGCTACTCCGCTGATCGAATCAAGAGTAAGATTCTGTATGTCT
GCATCTTTAACAAAGGAAGATATCGATTATTTACTGCGTCATGTTAGTGAAGTTGGTGAC
AAATTGAATTTGAAATCAAATTCCGGCAAATCCAGTTACGACGGTAAACGTCAAAGATGG
GACATCGAGGAAGTTATCAGGAGAACACCTGAAGATTGTAAGGACGACAAGTATTTTGTT
AATTGA

>SACE0D06688g.aa
MSTPANYTRVPLCEPEELPDDIQKENEYGTLDSPGHLYQVKSRHGKPLPEPVVDTPPYYI
SLLTYLNYLILIILGHVHDFLGMTFQKNKHLDLLEHDGLAPWFSNFESFYVRRIKMRIDD
CFSRPTTGVPGRFIRCIDRISHNINEYFTYSGAVYPCMNLSSYNYLGFAQSKGQCTDAAL
ESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKK
CLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTNRPWKKILIC
AEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDIL
MGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTISSLQTISGEICPG
QGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAV
VVVAYPATPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLKSNSGKSSYDGKRQRW
DIEEVIRRTPEDCKDDKYFVN*

Legend and notes

Lengths
The length, in codons, of coding sequences includes the stop codon, hence it is one unit longer than the protein length.

Genomic environment map
Click on the symbol of an element or a family to go to its corresponding page. Colors in the lane "protein encoding genes" indicate strandedness: shades of blue for direct orientation, shades of red for reverse orientation. Colors in the lane "protein family" are arbitrarly chosen in such a way that different protein families have different colors in the map.

Protein domain map
Domains are extracted from SwissProt files. Click on the symbol of a domain to extract the domain sequence.

Genemark image and list
Genemark computation of protein-coding potential of DNA was made from 1000 nucleotides upstream the open reading frame to 300 nucleotides downstream. Thus the open reading frame protein-coding potential appears on frame #3.

Sequences

Color	Nucleotide sequence and Coding sequence	Predicted translation product
RED	start and stop codons	Initial methionine and sequence end
BLUE	coding sequence	protein sequence
grey	non-coding sequence (upstream, downstream or intron)
grey	donor and acceptor splicing sites

Genetic Elements

SACE0D06688g

SACE0D06688g

Genomic environment map

Computed results

Homologs and Orthologs

Protein SACE0D06688p

Protein domain map

Computed results for SACE0D06688p

Gene Ontology terms

Sequence data

Nucleotide sequence

Coding sequence

Predicted translation product

Legend and notes