DEHA2G14322p_blastp.html
BLASTP 2.2.18 [Mar-02-2008]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= DEHA2G14322p (infer) YDR211W GCD6 Catalytic epsilon subunit of
the translation initiation factor eIF2B the guanine-nucleotide
exchange factor for eIF2 : similar to uniprot|P32501 Saccharomyces
cerevisiae [Debaryomyces hansenii CBS767]
(730 letters)
Database: Genolevures3.aa
48,939 sequences; 23,992,848 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
|DEHA2G14322p (infer) YDR211W GCD6 Catalytic epsilon subunit of t... 1507 0.0
|SAKL0H13090p (infer) YDR211W GCD6 Catalytic epsilon subunit of t... 816 0.0
|ERGO0G06292p Syntenic homolog of Saccharomyces cerevisiae YDR211... 780 0.0
|KLTH0F07942p (infer) YDR211W GCD6 Catalytic epsilon subunit of t... 777 0.0
|KLLA0A04235p (infer) YDR211W GCD6 Catalytic epsilon subunit of t... 774 0.0
|SACE0D09856p Catalytic epsilon subunit of the translation initia... 769 0.0
|ZYRO0A09284p (infer) YDR211W GCD6 Catalytic epsilon subunit of t... 737 0.0
|CAGL0C01221p (infer) YDR211w GCD6 : highly similar to uniprot|P3... 736 0.0
|YALI0B15708p (infer) YDR211w GCD6 translation initiation factor ... 575 e-164
|YALI0E21846p (infer) YOR260w GCD1 translation initiation factor ... 88 3e-17
|DEHA2F14718p (infer) YOR260W GCD1 Gamma subunit of the translati... 74 8e-13
|KLLA0C09570p (infer) YOR260W GCD1 Gamma subunit of the translati... 59 3e-08
|CAGL0D01034p (infer) YDL055c PSA1 mannose-1-phosphate guanyltran... 55 3e-07
|SAKL0H05742p (infer) YOR260W GCD1 Gamma subunit of the translati... 54 5e-07
|ERGO0A01760p Syntenic homolog of Saccharomyces cerevisiae YOR260... 54 7e-07
|KLTH0D12012p (infer) YOR260W GCD1 Gamma subunit of the translati... 54 9e-07
|SACE0D04136p GDP-mannose pyrophosphorylase (mannose-1-phosphate ... 53 1e-06
|CAGL0K08888p (infer) YOR260w GCD1 : similar to uniprot|P09032 Sa... 52 4e-06
>|DEHA2G14322p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
initiation factor eIF2B the guanine-nucleotide exchange
factor for eIF2 : similar to uniprot|P32501
Saccharomyces cerevisiae [Debaryomyces hansenii CBS767]
Length = 730
Score = 1507 bits (3901), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 730/730 (100%), Positives = 730/730 (100%)
Query: 1 MAPKNKKQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANA 60
MAPKNKKQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANA
Sbjct: 1 MAPKNKKQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANA 60
Query: 61 GVNEVYLMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISG 120
GVNEVYLMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISG
Sbjct: 61 GVNEVYLMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISG 120
Query: 121 DFLLVSGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDK 180
DFLLVSGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDK
Sbjct: 121 DFLLVSGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDK 180
Query: 181 NTGRCVFYQGIPPVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQEN 240
NTGRCVFYQGIPPVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQEN
Sbjct: 181 NTGRCVFYQGIPPVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQEN 240
Query: 241 FDYQYLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLV 300
FDYQYLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLV
Sbjct: 241 FDYQYLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLV 300
Query: 301 PDSNLLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQ 360
PDSNLLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQ
Sbjct: 301 PDSNLLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQ 360
Query: 361 IGNNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLS 420
IGNNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLS
Sbjct: 361 IGNNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLS 420
Query: 421 NNTRIVEKPIDRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYV 480
NNTRIVEKPIDRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYV
Sbjct: 421 NNTRIVEKPIDRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYV 480
Query: 481 SDNELDEESDSEYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSS 540
SDNELDEESDSEYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSS
Sbjct: 481 SDNELDEESDSEYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSS 540
Query: 541 ASMVSTDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEV 600
ASMVSTDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEV
Sbjct: 541 ASMVSTDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEV 600
Query: 601 RLATSKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCS 660
RLATSKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCS
Sbjct: 601 RLATSKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCS 660
Query: 661 NVDKSYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLRE 720
NVDKSYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLRE
Sbjct: 661 NVDKSYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLRE 720
Query: 721 AEEESEEESD 730
AEEESEEESD
Sbjct: 721 AEEESEEESD 730
>|SAKL0H13090p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
initiation factor eIF2B the guanine-nucleotide exchange
factor for eIF2 activity subsequently regulated by
phosphorylated eIF2 first identified as a negative
regulator of GCN4 expression : similar to uniprot|P32501
Saccharomyces cerevisiae [Lachancea kluyveri]
Length = 727
Score = 816 bits (2107), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 423/722 (58%), Positives = 534/722 (73%), Gaps = 29/722 (4%)
Query: 4 KNKKQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVN 63
K+ K+ E+VQD+R QAIVLTDSFETRFMPLTS+ PRCLLPLANVPLIEYTLEFLA AGVN
Sbjct: 14 KHGKKTELVQDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANVPLIEYTLEFLAKAGVN 73
Query: 64 EVYLMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGDFL 123
EVYL+C+SHA+Q+ EYIE SKW+ SPFK+STIMSLESRSVGDAMRDLDNRGLI+GDF+
Sbjct: 74 EVYLICASHAEQVNEYIENSKWNLPWSPFKVSTIMSLESRSVGDAMRDLDNRGLITGDFI 133
Query: 124 LVSGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDKNTG 183
LVSGD+VTN++F+KA+ AH++++ DKDHIVTM L+ AS HRTRS +P+TFI DK+
Sbjct: 134 LVSGDLVTNMEFDKALEAHRKQRATDKDHIVTMCLSKASQYHRTRS-YEPSTFIFDKSNN 192
Query: 184 RCVFYQGIPPVDG-KRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQENFD 242
RC++YQ IPP K++++ IDPELLED+E E +RNDLIDC VDICSP VP IFQENFD
Sbjct: 193 RCLYYQEIPPASSKKKTAVAIDPELLEDVE-EFTLRNDLIDCYVDICSPLVPAIFQENFD 251
Query: 243 YQYLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLVPD 302
YQYLR DFVKGVL+SDLLKK IYAYITD EYAAR ESW TYDA+SQD LARWCYPLV +
Sbjct: 252 YQYLRKDFVKGVLSSDLLKKHIYAYITD--EYAARAESWQTYDAISQDFLARWCYPLVLN 309
Query: 303 SNLLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIG 362
SNLLE SYSYE HIYKE V+LAQSCKIG CT+IG+ S +GEGT+I+ SVIGRNCQIG
Sbjct: 310 SNLLEDQSYSYESQHIYKEKDVVLAQSCKIGKCTAIGSGSKIGEGTNIENSVIGRNCQIG 369
Query: 363 NNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLSNN 422
N+TI NSY+WDNA+I DDS++ HSI+A N IG TL+ G +IG+NVVI D +
Sbjct: 370 ENITIRNSYVWDNAVIMDDSILKHSIVASNTRIGKNVTLNDGCIIGFNVVIDDNKIIPEG 429
Query: 423 TRIVEKPIDRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYVSD 482
+I P+++ + ++ DS ++ G E A D+VG+NG+G+LY +
Sbjct: 430 CKISGTPVEKSSQFLDTESYIDSSDDEENEEGMEEDVAPAR----DLVGENGIGYLY--E 483
Query: 483 NELDEESDSEYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSSAS 542
+E ++ D H + + Y++ L +SD SI+S + KK R +S+ S
Sbjct: 484 SEYSDDEDDTTDGDHVTNTLSYKLDELYLSDTSISSATTKHKKK---------RTMSTTS 534
Query: 543 MVSTDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEVRL 602
+ + + +++EDFEKEAIATV R+MENNHDLDTALLELNTLRMSMNVTYHEVR
Sbjct: 535 LYTDKEDD---DLDDEEDFEKEAIATVARAMENNHDLDTALLELNTLRMSMNVTYHEVRT 591
Query: 603 ATSKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQD--VCS 660
+T A++ ++ HFI T TL K+A K+F +WGLLFKRQ F++ E VDL+ II + V
Sbjct: 592 STVIAMLRRVYHFIATQTLGPKDAVTKVFAQWGLLFKRQAFDQEESVDLVNIIMEGVVEE 651
Query: 661 NVDKSYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLRE 720
N +K ILF ALN LY+ DI++E+ IY+WWD+ S + +V+ LT KWV+WL+
Sbjct: 652 NFEKP--DFILFSALNCLYDMDILDEDVIYQWWDTVSKDIKYE--EVKKLTEKWVEWLKN 707
Query: 721 AE 722
A+
Sbjct: 708 AD 709
>|ERGO0G06292p Syntenic homolog of Saccharomyces cerevisiae YDR211W (GCD6)
[Eremothecium gossypii]
Length = 731
Score = 780 bits (2013), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 408/717 (56%), Positives = 519/717 (72%), Gaps = 21/717 (2%)
Query: 7 KQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVNEVY 66
K+ E+VQD+R QA+VLTDSFETRFMPLT +PRCL+PLANVPLIEYTLEFLA AGV+EVY
Sbjct: 20 KRNEVVQDERLQAVVLTDSFETRFMPLTYEMPRCLMPLANVPLIEYTLEFLAKAGVHEVY 79
Query: 67 LMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGDFLLVS 126
L+C+SHA+Q+QEYI+ SKW+ SPFK+STI++LE+RSVGDAMRDLDNRGLI+GDF+LVS
Sbjct: 80 LICTSHAEQVQEYIDNSKWNLPWSPFKVSTILALEARSVGDAMRDLDNRGLITGDFILVS 139
Query: 127 GDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDKNTGRCV 186
GD+VTN++F++A+ AH+ R+ DK+HIVTM L+ A+ HRTRS +PA F+LDK+ RC+
Sbjct: 140 GDLVTNMEFDRALEAHRARRAEDKEHIVTMCLSTATQSHRTRS-CEPAVFMLDKSNDRCL 198
Query: 187 FYQGIPPVDGKR-SSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQENFDYQY 245
+YQ IP KR ++++IDPELLE +E E +RNDLIDC +DICSP VP IFQENFDYQY
Sbjct: 199 YYQDIPLASSKRKTAVDIDPELLEGVE-EFKLRNDLIDCHIDICSPLVPAIFQENFDYQY 257
Query: 246 LRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLVPDSNL 305
LR DFVKGVL+SDLLKK IYAYIT EYAARVESW TYDA+SQD LARWCYPLV DSNL
Sbjct: 258 LRRDFVKGVLSSDLLKKHIYAYIT--KEYAARVESWQTYDAISQDFLARWCYPLVLDSNL 315
Query: 306 LESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNNV 365
LE +YSYE H+YKE VILAQSCKIG CT+IG+ S++GEGT I+ SVIGRNCQIG NV
Sbjct: 316 LEDQTYSYESKHVYKEKDVILAQSCKIGKCTAIGSGSTIGEGTFIENSVIGRNCQIGANV 375
Query: 366 TINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLSNNTRI 425
I NSYIW+N+II D+SV++HSI+A A++GS TL G VIG+NVV+ + + TRI
Sbjct: 376 KIINSYIWENSIIGDNSVLNHSIVAAGAKLGSAVTLEDGCVIGFNVVVASSKTIPSGTRI 435
Query: 426 VEKPIDRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYVSDNEL 485
PI S + E D + + + + +VG++GVG++Y SD+
Sbjct: 436 SAAPITVSSMSVPTPSYSSDEDSDEDSGLHPATRSKSTAKAVQLVGESGVGYIYESDDSD 495
Query: 486 DEESDSEY-GVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSSASMV 544
D E + G N + +M L +SD SI S S K + R LS+AS
Sbjct: 496 DSEETDDCDGAGAN--TLCTRMDELYLSDSSIYSASKTK----------KRRTLSTASYY 543
Query: 545 STDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEVRLAT 604
TD+E G + EE+EDFEKEAIATV+R+ME+NHD+DTALLELNTLRMS+NVTYHEVR AT
Sbjct: 544 -TDWEDGSDASEEEEDFEKEAIATVERAMEHNHDIDTALLELNTLRMSLNVTYHEVRAAT 602
Query: 605 SKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCSNVDK 664
A++ ++ HFI T TL K+A K+F WG LF+RQ F E VDL+ +I ++
Sbjct: 603 VSAMLKRVYHFIATQTLGPKDAVAKVFAHWGPLFRRQAFTAAEYVDLMDVILHRVVSMRF 662
Query: 665 SYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLREA 721
ILF + LY+ DI++E+ +Y+WW + ++ V+TLT KWVDWL+ A
Sbjct: 663 DRPDFILFCVYSCLYDSDILDEDVVYQWWAAAAADPAH--ADVKTLTAKWVDWLQTA 717
>|KLTH0F07942p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
initiation factor eIF2B the guanine-nucleotide exchange
factor for eIF2 activity subsequently regulated by
phosphorylated eIF2 first identified as a negative
regulator of GCN4 expression : similar to uniprot|P32501
Saccharomyces cerevisiae [Kluyveromyces thermotolerans]
Length = 726
Score = 777 bits (2007), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 395/718 (55%), Positives = 521/718 (72%), Gaps = 24/718 (3%)
Query: 7 KQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVNEVY 66
K+ E+VQD+R QAIVLTDSFETRFMPLT++ PRCLLPLANVPLIEYTLEFLA AG +EVY
Sbjct: 17 KKPEVVQDERLQAIVLTDSFETRFMPLTAVKPRCLLPLANVPLIEYTLEFLAKAGASEVY 76
Query: 67 LMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGDFLLVS 126
L+C+SHADQ+ YIE SKW+ SPF++STIMSLESRSVGDAMRDLDNRG+I+GDF+LVS
Sbjct: 77 LVCASHADQVSAYIETSKWNMPWSPFRVSTIMSLESRSVGDAMRDLDNRGVITGDFILVS 136
Query: 127 GDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDKNTGRCV 186
GD+VTN++F+KA+ H+++K DKDHIVTM L+ AS +RTR +PA FILDK+ RC+
Sbjct: 137 GDLVTNMEFDKALEFHRKKKAEDKDHIVTMCLSKASQFYRTRCH-EPAAFILDKSNNRCL 195
Query: 187 FYQGIPPVDGK-RSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQENFDYQY 245
+YQ IP K ++S+ IDPELLED+ DE +RNDLIDC VDICSP VP IFQENFDYQY
Sbjct: 196 YYQDIPLASSKHKTSLAIDPELLEDV-DEFTLRNDLIDCHVDICSPLVPAIFQENFDYQY 254
Query: 246 LRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLVPDSNL 305
LR DFVKGVLTSDLLKK+IY++ITD EYAARVESW TYDA+SQD +ARWCYP+V ++NL
Sbjct: 255 LRRDFVKGVLTSDLLKKSIYSFITD--EYAARVESWQTYDAISQDFIARWCYPMVLNTNL 312
Query: 306 LESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNNV 365
L+ +YSYE HIYKE V+LAQSCKIG T+IG+ S +GEGT I+ SVIGRNC IG N+
Sbjct: 313 LDDQTYSYESEHIYKEKDVVLAQSCKIGKRTAIGSGSKIGEGTKIQNSVIGRNCYIGENI 372
Query: 366 TINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLSNNTRI 425
I +S+IWDN +I S+++HS++A +IGS L+ G VIG+NV++ D + + TRI
Sbjct: 373 IIRDSFIWDNTVIGAKSLIEHSLVASGVKIGSNVILNDGCVIGFNVMVDDNMEIPMGTRI 432
Query: 426 VEKPIDRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYVSDNEL 485
E P+ + F S S++ ++ + + I+ ++VG +GVG++Y SD
Sbjct: 433 SETPVRKKATQFSDSASYEDDETAKQDESTKVISP-----AYELVGTDGVGYVYDSDKAE 487
Query: 486 DEESDSEYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSSASMVS 545
D++ S V N + Y+ L +SDDSI+S + + KK R +S+ S+ +
Sbjct: 488 DDDDASVIDVVTN--SLTYKFDDLYLSDDSISSTAGKRKKK---------RSMSTNSIYT 536
Query: 546 -TDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEVRLAT 604
+ + EE++EDF EAIATV+R+MENNHDLDTALLELNTLRMS+NV+YHEVR AT
Sbjct: 537 DREGDDYEDDEEDEEDFAVEAIATVERAMENNHDLDTALLELNTLRMSINVSYHEVRSAT 596
Query: 605 SKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCSNVDK 664
AL+ ++ HFI T TL K+A +K+F++WG++F+RQ F++ E VDL ++ +
Sbjct: 597 VVALLRRVYHFIATQTLGAKDAVQKVFSQWGMMFQRQAFDQEEFVDLSNLLLEKVVAQGF 656
Query: 665 SYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLREAE 722
ILF AL LY+ DI++E+ +Y WWD S + Q +TLT KW++WL+ A+
Sbjct: 657 EKPEFILFSALTCLYDLDILDEDAVYTWWDQVSQ--EEKYSQAKTLTAKWIEWLKTAD 712
>|KLLA0A04235p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
initiation factor eIF2B the guanine-nucleotide exchange
factor for eIF2 activity subsequently regulated by
phosphorylated eIF2 first identified as a negative
regulator of GCN4 expression : similar to uniprot|P32501
Saccharomyces cerevisiae [Kluyveromyces lactis NRRL
Y-1140]
Length = 736
Score = 774 bits (1999), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 409/736 (55%), Positives = 535/736 (72%), Gaps = 40/736 (5%)
Query: 2 APKNKKQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAG 61
A +NKKQ E+VQD+R QAIVLTDSFETRFMPLTS+ PRCLLPLAN+PLIEYTLEFLA AG
Sbjct: 11 ANQNKKQ-EVVQDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEYTLEFLAKAG 69
Query: 62 VNEVYLMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGD 121
VNEVYL+C+SH +QIQEYI++SKWS +PFK++TIMSLESRSVGDAMRD+DNRGLI+GD
Sbjct: 70 VNEVYLICASHGEQIQEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDVDNRGLITGD 129
Query: 122 FLLVSGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDKN 181
F+LVSGD+VTN+DFEKA++ HKQR++ DKDHIVTM L+ A+ H+TRS +PATFI DK+
Sbjct: 130 FVLVSGDLVTNMDFEKALDIHKQRRKADKDHIVTMCLSKATQFHKTRSH-EPATFIFDKS 188
Query: 182 TGRCVFYQGIPPVDGK-RSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQEN 240
RC++YQ IP + +++I+IDPELLE + DE V+RNDLIDC VDICSPHVP IFQEN
Sbjct: 189 NDRCIYYQDIPLASSREKTTIDIDPELLEGV-DEFVLRNDLIDCHVDICSPHVPAIFQEN 247
Query: 241 FDYQYLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLV 300
FDYQ+LR DFV+GVL+SDLLKK IY YITD EY R ESW TYDA+SQD +ARWCYPLV
Sbjct: 248 FDYQFLRRDFVRGVLSSDLLKKHIYGYITD--EYTTRAESWQTYDAISQDFIARWCYPLV 305
Query: 301 PDSNLLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQ 360
++NLL+ +YSYE HIYKE V+LAQSCKI T+IG+ S +GEGT I+ SV+GRNC+
Sbjct: 306 LNANLLKGQTYSYESQHIYKEKDVVLAQSCKIKKNTAIGSGSKIGEGTVIENSVVGRNCK 365
Query: 361 IGNNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLS 420
IG+N+ I NSYIWDN +I D++ ++HS++A + ++GS TL+ G++IG+NVVI D + +
Sbjct: 366 IGSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSIIGFNVVIDDNVTIP 425
Query: 421 NNTRIVEKPIDRDDESF-ESSRSFDS--EQEDGKT-----------NGGEYINADQSVND 466
T+I P+ R+ F +++ + S E E+G T N E +A ++
Sbjct: 426 VGTKISAVPVQRNTAQFLDTAHNLSSSDEDEEGSTFTRNSSSLSISNSDEVADAKIKLSK 485
Query: 467 IDVVGDNGVGFLYVSDNELDEESDS-EYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSK 525
+VG NG G LY SD+E ++E S E G+++ + Y+ + +SD SI+S++
Sbjct: 486 -QLVGPNGRGVLYESDDEDEDEDGSTEKGIANT---LTYRDDDIYLSDTSISSITQ---- 537
Query: 526 KFHRRTSSRNRRLSSASMVSTDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLE 585
++R+ + SM S Y E+E+EDFEKEAIATV+R++ENNHDLDT++LE
Sbjct: 538 --------KHRKRRTMSMTSI-YTDYEGEEDEEEDFEKEAIATVERAIENNHDLDTSMLE 588
Query: 586 LNTLRMSMNVTYHEVRLATSKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEE 645
LNTLRMSMNVTYHEVR A+ A+ ++ HF+ T TL K+A K+ +WG +FKRQ F+
Sbjct: 589 LNTLRMSMNVTYHEVRNASVIAIFRRVYHFVATQTLGPKDAVTKVLQQWGPVFKRQAFDS 648
Query: 646 FEQVDLLQIIQDVCSNVDKSYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLV 705
E +DL+ II D + ILF N+LY+ DI+EE+ IYKWWDS S +
Sbjct: 649 DEFIDLMNIILDRVLDQKFDKPDFILFHVYNVLYDLDILEEDVIYKWWDSVS--GDSKYS 706
Query: 706 QVRTLTGKWVDWLREA 721
+V L KWVDWL+ A
Sbjct: 707 EVTALLAKWVDWLKTA 722
>|SACE0D09856p Catalytic epsilon subunit of the translation initiation factor
eIF2B, the guanine-nucleotide exchange factor for eIF2;
activity subsequently regulated by phosphorylated eIF2;
first identified as a negative regulator of GCN4
expression [Saccharomyces cerevisiae]
Length = 712
Score = 769 bits (1986), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 407/716 (56%), Positives = 522/716 (72%), Gaps = 42/716 (5%)
Query: 14 DDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVNEVYLMCSSHA 73
+DR QA+VLTDS+ETRFMPLT++ PRCLLPLANVPLIEYTLEFLA AGV+EV+L+CSSHA
Sbjct: 24 EDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLIEYTLEFLAKAGVHEVFLICSSHA 83
Query: 74 DQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGDFLLVSGDVVTNI 133
+QI +YIE SKW+ SPFKI+TIMS E+R GD MRDLDNRG+I+GDF+LVSGDV+TNI
Sbjct: 84 NQINDYIENSKWNLPWSPFKITTIMSPEARCTGDVMRDLDNRGIITGDFILVSGDVLTNI 143
Query: 134 DFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDKNTGRCVFYQGIP- 192
DF K + HK+ DKDHI TM L+ AS +TR+ ++PA F+LDK+T RC++YQ +P
Sbjct: 144 DFSKMLEFHKKMHLQDKDHISTMCLSKASTYPKTRT-IEPAAFVLDKSTSRCIYYQDLPL 202
Query: 193 PVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQENFDYQYLRSDFVK 252
P +++SI IDPELL+++ DE VIRNDLIDC +DIC+ HVP IFQENFDYQ LR+DFVK
Sbjct: 203 PSSREKTSIQIDPELLDNV-DEFVIRNDLIDCRIDICTSHVPLIFQENFDYQSLRTDFVK 261
Query: 253 GVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLVPDSNLLESNSYS 312
GV++SD+L K IYAY+TD EYA RVESW TYD +SQD L RWCYPLV DSN+ + +YS
Sbjct: 262 GVISSDILGKHIYAYLTD--EYAVRVESWQTYDTISQDFLGRWCYPLVLDSNIQDDQTYS 319
Query: 313 YEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNNVTINNSYI 372
YE HIYKE V+LAQSCKIG CT+IG+ + +GEGT I+ SVIGRNCQIG N+ I NS+I
Sbjct: 320 YESRHIYKEKDVVLAQSCKIGKCTAIGSGTKIGEGTKIENSVIGRNCQIGENIRIKNSFI 379
Query: 373 WDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLSNNTRIVEKPIDR 432
WD+ II ++S++DHS+IA NA +GS L+ G +IG+NV I D + L NT+I P+
Sbjct: 380 WDDCIIGNNSIIDHSLIASNATLGSNVRLNDGCIIGFNVKIDDNMDLDRNTKISASPLKN 439
Query: 433 DDESFESSRSFDSEQEDGKTNGGEYINADQSVND----IDVVGDNGVGFLYVSDNELDEE 488
SR +D+E + DQ ++D + +VGD GVG++Y S+ DE+
Sbjct: 440 -----AGSRMYDNESNE---------QFDQDLDDQTLAVSIVGDKGVGYIYESEVSDDED 485
Query: 489 SDSEYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSSASMVSTDY 548
S +E + + Q+ L +SDDSI+S + K+KK RR S + + TD
Sbjct: 486 SSTE--ACKEINTLSNQLDELYLSDDSISSATK-KTKK---------RRTMSVNSIYTDR 533
Query: 549 EGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEVRLATSKAL 608
E SE EDEDFEKE IATV+R+MENNHDLDTALLELNTLRMSMNVTYHEVR+AT AL
Sbjct: 534 EEID-SEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSMNVTYHEVRIATITAL 592
Query: 609 IHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCSNVDKSYNG 668
+ ++ HFI T TL K+A K+FN+WGLLFKRQ F+E E +DL+ II + V++S++
Sbjct: 593 LRRVYHFIATQTLGPKDAVVKVFNQWGLLFKRQAFDEEEYIDLMNIIMEKI--VEQSFDK 650
Query: 669 R--ILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLREAE 722
ILF AL LY+ DI+EE+ IYKWWD+ S+ D +V+ LT KWV+WL+ A+
Sbjct: 651 PDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYD--EVKKLTVKWVEWLQNAD 704
>|ZYRO0A09284p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
initiation factor eIF2B the guanine-nucleotide exchange
factor for eIF2 activity subsequently regulated by
phosphorylated eIF2 first identified as a negative
regulator of GCN4 expression : similar to uniprot|P32501
Saccharomyces cerevisiae [Zygosaccharomyces rouxii]
Length = 718
Score = 737 bits (1903), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 378/721 (52%), Positives = 496/721 (68%), Gaps = 30/721 (4%)
Query: 4 KNKKQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVN 63
K ++E+VQDDR QAIVLTDSFETRFMPL++ PRCLLPLANVPL+EYTLEFLA A V
Sbjct: 7 KAHPKEEMVQDDRLQAIVLTDSFETRFMPLSNDKPRCLLPLANVPLLEYTLEFLAKAPVK 66
Query: 64 EVYLMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGDFL 123
EVYL+CS+HA I +YIE SKWS SPFK+ TIMS E+RSVGDAMRDLDN+G+I+GDF+
Sbjct: 67 EVYLVCSAHATLISDYIEASKWSFPWSPFKVFTIMSPEARSVGDAMRDLDNKGVIAGDFV 126
Query: 124 LVSGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDKNTG 183
L+SGD VTN+DF+K + HK+ DKDHIVT L+ A+ HRTR+ +PA+FILDK+
Sbjct: 127 LMSGDAVTNLDFDKFWDFHKRMHAKDKDHIVTTCLSKATQFHRTRA-FEPASFILDKSDN 185
Query: 184 RCVFYQGIP-PVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQENFD 242
RC++YQ IP P ++S+ IDP+LLE + DE V+RNDLIDC +DICSP VP IFQENFD
Sbjct: 186 RCLYYQEIPLPSSRVKTSVEIDPDLLEGV-DEFVLRNDLIDCRIDICSPLVPAIFQENFD 244
Query: 243 YQYLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLVPD 302
YQ LRSDF+KGVL+SDLL+K +YAYIT+ EYAARVESW +YD++SQD + RWCYPLV D
Sbjct: 245 YQMLRSDFIKGVLSSDLLRKHVYAYITE--EYAARVESWQSYDSISQDFIGRWCYPLVLD 302
Query: 303 SNLLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIG 362
SNL+ +YSYE NHIYKE V+LAQSCKIG CT+IG+ + +GE ++ VIGRNC IG
Sbjct: 303 SNLMPDQTYSYESNHIYKEQGVVLAQSCKIGKCTAIGSRTKIGESALVENCVIGRNCYIG 362
Query: 363 NNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLSNN 422
+ I +S+IWDN +I ++SV++HSI+A ++G+ L+ G +IG+NVVI DG L
Sbjct: 363 SGAVIRDSHIWDNTVIGNNSVINHSIVASGTKLGTNVVLNDGCIIGFNVVIEDGKELPRG 422
Query: 423 TRIVEKPI-DRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYVS 481
R+ P+ D +D +F S D E+ K D ++ G G G++Y
Sbjct: 423 VRVNGTPVKDSEDNAFGLSDEEDEEETPEK---------DNPEIAFELCGTKGRGYIY-E 472
Query: 482 DNELDEESDSEYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSSA 541
D ++E D G SG+ +++ + +SD SI+SV T S+ +R S
Sbjct: 473 DPLSEDEHDLPIG-EEMVSGLSHRLDEVYLSDSSISSV-----------TKSKKKRTMST 520
Query: 542 SMVSTDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEVR 601
+ TD E P E++EDF E +ATV R++ENNHDLDTALLELNTLRMS+NV+YHEVR
Sbjct: 521 NSAYTDREEDPTEFEDEEDFGVEGVATVKRAIENNHDLDTALLELNTLRMSLNVSYHEVR 580
Query: 602 LATSKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCSN 661
T AL+ ++ HFI T TL K+A K+F +WG +F+R+ F+ E VDL+ I+ +
Sbjct: 581 TVTVVALLDRVYHFIATQTLGPKDAANKVFTRWGPMFRREAFDPDEYVDLMNIVMEQVVE 640
Query: 662 VDKSYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLREA 721
+ ILF A N LY+ DI+EEE IY WW S D ++ L KW++WL+EA
Sbjct: 641 QELEKGDLILFSAFNALYDSDILEEEIIYDWWSHVSKDPKFD--DIKKLVAKWIEWLKEA 698
Query: 722 E 722
+
Sbjct: 699 D 699
>|CAGL0C01221p (infer) YDR211w GCD6 : highly similar to uniprot|P32501
Saccharomyces cerevisiae [Candida glabrata CBS 138]
Length = 717
Score = 736 bits (1899), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 379/716 (52%), Positives = 499/716 (69%), Gaps = 19/716 (2%)
Query: 14 DDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVNEVYLMCSSHA 73
+DR QA+VLTDS+ETRFMPLT+ PRCL+PLANVPLIEYTLEFLA AG +EV+L CS+HA
Sbjct: 20 EDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEYTLEFLAKAGADEVFLACSAHA 79
Query: 74 DQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGDFLLVSGDVVTNI 133
Q+ EYIE+SKW+ SPFK++T+M+ E+RS+GD MRDLDNRG+I+GDF+LVSGDVVTNI
Sbjct: 80 KQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDNRGIITGDFILVSGDVVTNI 139
Query: 134 DFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDKNTGRCVFYQGIP- 192
DF K ++ HK+ DKDHI TM L AS + TR+ ++PA F+L+K+T RC++YQ +P
Sbjct: 140 DFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRT-IEPACFVLEKSTNRCLYYQDMPS 198
Query: 193 PVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQENFDYQYLRSDFVK 252
P R +++DPELLE++ D +RNDLIDC +DIC+PHVP IFQ+NFDYQ LRSDF+K
Sbjct: 199 PNSRSRKVLDVDPELLENV-DSFSMRNDLIDCRIDICTPHVPPIFQDNFDYQSLRSDFLK 257
Query: 253 GVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLVPDSNLLESNSYS 312
GV++SDLL K IYAYITD EYA R ESW ++D +SQD L R CYPLV +SN+ E +YS
Sbjct: 258 GVISSDLLGKHIYAYITD--EYAVRAESWHSFDTISQDFLGRLCYPLVLESNIQEDQTYS 315
Query: 313 YEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNNVTINNSYI 372
YE HIYKE V+LAQSCKIG CT+IG + +GE T ++ VIGRNC IG N+ I NSYI
Sbjct: 316 YESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVIGRNCIIGENINIKNSYI 375
Query: 373 WDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLSNNTRIVEKPIDR 432
WDN +I + + H I+A N ++G+ L+ G +IG++VVI D + ++I P+
Sbjct: 376 WDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVIEDNKEIPAGSKISSVPV-A 434
Query: 433 DDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYVSDNELDEESDSE 492
S + +++D + + + Q ++VG++GVG++Y SD EE D E
Sbjct: 435 SSRSRLPASDGYDDEDDDEEYSETFDDTTQQALASELVGEHGVGYVYESDASDIEEYD-E 493
Query: 493 YGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSSASMVSTDYEGGP 552
+ + Q+ + +SD+SI+S KK T+S V TD E
Sbjct: 494 DECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNS----------VYTDREDYL 543
Query: 553 FSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEVRLATSKALIHKI 612
EEE EDF E IATV+R++EN+HDLDTALLELNTLRMSMNVTYHEVRLAT+ AL+ ++
Sbjct: 544 SDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLATATALVRRV 603
Query: 613 IHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCSNVDKSYNGRILF 672
HFI T TL KEA K+F +WG LF RQVFE E +DL+ I+ ++ + ILF
Sbjct: 604 YHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQKFEKPEFILF 663
Query: 673 MALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLREAEEESEEE 728
ALN LY+ DI+EE++IY+WWD+ S + D QV+TLT KWVDWLR AEEES++E
Sbjct: 664 SALNTLYDNDILEEDSIYEWWDNVSQDSKYD--QVKTLTAKWVDWLRNAEEESDDE 717
>|YALI0B15708p (infer) YDR211w GCD6 translation initiation factor eIF2b epsilon 81
kDa subunit : similar to uniprot|P32501 Saccharomyces
cerevisiae [Yarrowia lipolytica CLIB122]
Length = 681
Score = 575 bits (1483), Expect = e-164, Method: Compositional matrix adjust.
Identities = 316/728 (43%), Positives = 447/728 (61%), Gaps = 71/728 (9%)
Query: 1 MAPKNKKQKE----IVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEF 56
M PK K K I +D R QA++L DS++ RF PLT PRCLLPLAN PL+EYT EF
Sbjct: 1 MPPKKKNAKPQKSAIDKDFRLQAVILADSYQARFQPLTKDYPRCLLPLANTPLLEYTFEF 60
Query: 57 LANAGVNEVYLMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRG 116
LA AGV EV+LMC SHAD+I+EYI+ SKWS +SPF+I T ES SVGDAMRDLD G
Sbjct: 61 LAKAGVCEVFLMCCSHADKIEEYIKTSKWSDSHSPFEIHTKKLTESMSVGDAMRDLDGTG 120
Query: 117 LISGDFLLVSGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATF 176
I+ DFLLVSGDVV+NIDF + H QRKQ DK+ ++TMVL A HRTRS+++P F
Sbjct: 121 SITSDFLLVSGDVVSNIDFTPVLEQHLQRKQDDKNAMMTMVLRQADAFHRTRSRIEPGLF 180
Query: 177 ILDKNTGRCVFYQGIPPVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQI 236
+L+ T C+ Y+ + ++ SI++D ELL D + + IRNDLIDC +D+CS V
Sbjct: 181 VLNDKTSECLRYEELS-LNNPTGSIDLDGELLND-DATLSIRNDLIDCHIDLCSIDVLAQ 238
Query: 237 FQENFDYQYLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWC 296
F ENFDY LRSDFVK +LTS++L K IYA+I + YAARV S TY AV++D+++R+
Sbjct: 239 FTENFDYSTLRSDFVKNILTSEILGKKIYAHIVTDA-YAARVRSLQTYSAVTKDIVSRYS 297
Query: 297 YPLVPDSNLLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIG 356
YP+VPDSNL++ ++SY+ HIYKE V+LAQSC IGS + +G +SVGE + +K +VIG
Sbjct: 298 YPVVPDSNLMDDQTFSYQMGHIYKEKGVVLAQSCVIGSRSLVGRGTSVGERSMVKDTVIG 357
Query: 357 RNCQIGNNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDG 416
R+C+I NV + +S+IW N II+DD V+ ++A A + G ++ PG++IG+ V +
Sbjct: 358 RDCKISTNVNLVDSFIWSNVIIEDDVTVNGGLVADGAILKKGCSVGPGSIIGHGVTV--- 414
Query: 417 IHLSNNTRIVEKPIDRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVG 476
E+G+ G Y+ V D G
Sbjct: 415 -------------------------------EEGQKIEGTYL-----------VLDAGES 432
Query: 477 FLYVSDNELDEESDSEYGVSHNYSGIIYQMSSLNVSDDSI---ASVSNAKSKKFHRRTSS 533
+ + ++ D + D++ + N ++Y + LN+SD SI + + + +
Sbjct: 433 IPFDAIDDDDSDFDTDDEFNANVGSLVYNLKELNLSDTSINDHCYEDDENIRAVAPKKKT 492
Query: 534 RNRRLSSASMVSTDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSM 593
R R S+ S VS ++E ++F+KEAIA++DR+ ++NH++D A LEL TLRMS
Sbjct: 493 RRRLSSTVSNVSDNHE---------DEFQKEAIASLDRAFQDNHEIDIAALELGTLRMSS 543
Query: 594 NVTYHEVRLATSKAL---IHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVD 650
NV Y EVR A+ KA+ I ++++ TD D K T+K++ KW LF++QVFE +Q+D
Sbjct: 544 NVPYEEVRAASVKAINGYITRVLNMGVTD--DHKVPTQKVWGKWAELFEKQVFEPADQID 601
Query: 651 LLQIIQDVCSNVDKSYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTL 710
LL I+ CS + ILF A+ LY+ D+++E I +WW + + ++ VRTL
Sbjct: 602 LLNILLKDCSR--RPVGNYILFAAVQSLYDADVLDEHVIVRWWHQQPEDVSPEIASVRTL 659
Query: 711 TGKWVDWL 718
GKWV WL
Sbjct: 660 LGKWVTWL 667
>|YALI0E21846p (infer) YOR260w GCD1 translation initiation factor eIF2bgamma
subunit : similar to uniprot|P09032 Saccharomyces
cerevisiae [Yarrowia lipolytica CLIB122]
Length = 483
Score = 88.2 bits (217), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 109/423 (25%), Positives = 188/423 (44%), Gaps = 56/423 (13%)
Query: 30 FMPLTSI----LPRCLLPLANVPLIEYTLEFLANAGVNEVYLMCSSHAD-QIQEYIEKSK 84
PL+S+ +P+ LLP+ANVP+I+YTL++ +V++ CS+ + +I Y++ K
Sbjct: 17 MAPLSSVRASGVPKALLPMANVPVIDYTLKWCETIPNPKVFVCCSTADEAEISAYVDSFK 76
Query: 85 WSSKNSPFKIS-TIMSLESRSVGDAMRDLDNRGLISGDFLLVSGDVVTNIDFEKAMNAHK 143
S + TI S GD + +L RG S DF++V D +T+I ++ ++
Sbjct: 77 AEHSTSVVASNVTICSKTDAKSGDFILEL-TRGEPS-DFIVVGCDFITDIPASSLVDTYR 134
Query: 144 QRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFI--------LDKNTGRCVFYQGIPPVD 195
R D D ++T P T VD + + LD T R + ++
Sbjct: 135 SR---DSDSLLTAFYYP-----NTLENVDKKSLLKDVTVHSSLDSRTPRLLDSYSRDYIE 186
Query: 196 GKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQENFDYQYLRSDFVKGVL 255
K++ + I +L +V L++ V C+ V ++ E ++ +
Sbjct: 187 NKKT-MPIRRSMLWHFPKSLV-STQLLNASVYFCTADVCRVITET------QAAPEEDST 238
Query: 256 TSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLAR-WCY--PLVPDS-NLLESNSY 311
D ++ + E + +D V +D+ R W + PL S +L+SN++
Sbjct: 239 DEDPDTRSSSPVRQEQEEAHTILAKGRQWDRVVRDIARRSWAHAKPLKSVSLCVLDSNTF 298
Query: 312 SYEFN-HIYKE-DKVILAQSCK-----------------IGSCTSIGTNSSVGEGTSIKK 352
+ N Y E ++VIL K +G + +G + +GE TSIK+
Sbjct: 299 ARANNLSAYMEMNRVILKARAKANATAQKPAPAVKGAATVGVDSLVGEETQLGERTSIKR 358
Query: 353 SVIGRNCQIGNNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTV-IGYNV 411
SV+G NC IG IN I+D A I DD +++ ++ +G+ A L+ V GY V
Sbjct: 359 SVVGNNCTIGKRCRINGCVIFDGAFIADDVTLENCLVGTKTTVGTKAKLTGCNVEGGYKV 418
Query: 412 VIG 414
G
Sbjct: 419 EAG 421
>|DEHA2F14718p (infer) YOR260W GCD1 Gamma subunit of the translation initiation
factor eIF2B : weakly similar to uniprot|P09032
Saccharomyces cerevisiae [Debaryomyces hansenii CBS767]
Length = 477
Score = 73.6 bits (179), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 104/473 (21%), Positives = 198/473 (41%), Gaps = 85/473 (17%)
Query: 17 FQAIVLTDSFETRFMPLTSI----LPRCLLPLANVPLIEYTLEFLANAGVNEVYLMCSS- 71
F A++L S + P + + +P+ LLP+AN P+I+Y LE+ A +V ++C +
Sbjct: 3 FHAVILCGSGKA-LSPFSQVRSTGMPKALLPIANRPMIDYVLEWCEKAFFPKVTVVCDTD 61
Query: 72 HADQIQEYIEKSKWSSKNSPFKIST---------------IMSLESRSVGDAMRDLDNRG 116
++Q+Q+ +++ I+ L+S S G+ + L
Sbjct: 62 SSEQVQKALDQYNSEKSKKEKAKEDADGDDDDSSFSRSVEILGLDSSSSGEVLYHLYKTS 121
Query: 117 LISGD--FLLVSGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQV-DP 173
+ + F+++ D +TN+ + + A++ R + D +V +R + + D
Sbjct: 122 ALKTNPHFVILPCDFITNLPPQVLIEAYRNRNESDLGLMV---------YYRNQLDIEDK 172
Query: 174 ATFILDKNTGRCVFYQGIPPVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHV 233
+ I KN Y +P DG+ ++I + D + IR + C + +
Sbjct: 173 KSKIFPKNY---TIYSDLP--DGQCQLLDIYSKEDIDFHKTLQIRTQM---CWKFPNSTI 224
Query: 234 P------QIFQENFDYQYLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAV 287
+F + D + D S ++I I D S SW D
Sbjct: 225 STKLLNGSVFFGSVDRIFAVFDQEDKCTESYFHDRSITKVIRDLSR-----RSWKHSDP- 278
Query: 288 SQDVLARWCYPLVPDSN----------LLESNSYSYEFNHIYK----------EDKVILA 327
+D + + ++PD L+E+N + + + K +DK
Sbjct: 279 -KDTVG---FCILPDQATFFRVNNTPVLMEANRHFMKLQAMAKGQHQQQTSHPKDKA--- 331
Query: 328 QSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNNVTINNSYIWDNAIIKDDSVVDHS 387
S IG SIG N+SVGE T++K++++G +C IG V + I +N I+DD +++
Sbjct: 332 -SANIGIDCSIGENTSVGEKTNVKRTIVGSSCSIGKRVKLTGCLILNNITIEDDVQLENC 390
Query: 388 IIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLSNNTRI---VEKPIDRDDESF 437
I+ I S + L+ V ++ + G H +T + +E ++ D+E F
Sbjct: 391 ILGNGVIIRSKSRLTNCNVES-SLEVAKGTHSKGDTLLCLSLEGIVEDDEEEF 442
>|KLLA0C09570p (infer) YOR260W GCD1 Gamma subunit of the translation initiation
factor eIF2B the guanine-nucleotide exchange factor for
eIF2 activity subsequently regulated by phosphorylated
eIF2 first identified as a negative regulator of GCN4
expression : similar to uniprot|P09032 Saccharomyces
cerevisiae [Kluyveromyces lactis NRRL Y-1140]
Length = 494
Score = 58.5 bits (140), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 1/110 (0%)
Query: 303 SNLLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIG 362
S +ESN Y + + + S IG+ + +G N ++ E T+IK+SV+G NC++G
Sbjct: 331 SAYMESNRYVLKIKQTAIQQRTTDGSSA-IGADSMVGNNCAILEKTNIKRSVLGDNCKVG 389
Query: 363 NNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVV 412
I + DN I D++ +++ II NA+IG + L+ V G +V
Sbjct: 390 KRCRIVGCVVLDNVEIDDETQLENVIIGRNAKIGKKSKLTNCYVEGSYIV 439
>|CAGL0D01034p (infer) YDL055c PSA1 mannose-1-phosphate guanyltransferase : highly
similar to uniprot|P41940 Saccharomyces cerevisiae
[Candida glabrata CBS 138]
Length = 361
Score = 55.1 bits (131), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 33/130 (25%), Positives = 65/130 (50%), Gaps = 8/130 (6%)
Query: 17 FQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVNEVYLMCSSHADQI 76
+ ++L + TR PLT +P+ L+ N P+I + +E LANAGV ++ L + + +
Sbjct: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNYRPEVM 60
Query: 77 QEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGD---FLLVSGDVVTNI 133
E ++K + + +S S+E+ +G A ++ D F +++ DV+
Sbjct: 61 VETLQKYEKE-----YGVSITFSVETEPLGTAGPLKLAEKVLKKDNSPFFVLNSDVICEY 115
Query: 134 DFEKAMNAHK 143
F++ + HK
Sbjct: 116 PFKELADFHK 125
>|SAKL0H05742p (infer) YOR260W GCD1 Gamma subunit of the translation initiation
factor eIF2B the guanine-nucleotide exchange factor for
eIF2 activity subsequently regulated by phosphorylated
eIF2 first identified as a negative regulator of GCN4
expression : similar to uniprot|P09032 Saccharomyces
cerevisiae [Lachancea kluyveri]
Length = 500
Score = 54.3 bits (129), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 28/77 (36%), Positives = 46/77 (59%)
Query: 332 IGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNNVTINNSYIWDNAIIKDDSVVDHSIIAG 391
IG+ + +G NS++ E T+IK+SV+G+NC++G I S I D I D++ +++ II
Sbjct: 365 IGADSVVGANSTILEKTNIKRSVLGKNCKVGKRCRIVGSIILDGVEIDDETGLENVIIGK 424
Query: 392 NAEIGSGATLSPGTVIG 408
+IG L+ V G
Sbjct: 425 FGKIGKKCKLTNCYVEG 441
>|ERGO0A01760p Syntenic homolog of Saccharomyces cerevisiae YOR260W (GCD1)
[Eremothecium gossypii]
Length = 498
Score = 53.9 bits (128), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
Query: 303 SNLLESNSYSYEFNHIYKEDKV-ILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQI 361
S +E+N Y + V + S IG+ + IG + ++ T++K+SV+G NC+I
Sbjct: 333 SAYMEANRYILKIKSASTSHTVPVTGSSSAIGADSVIGASCTILGKTNVKRSVVGANCKI 392
Query: 362 GNNVTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGY 409
GN I S + D A I D+ +++ I+ ++G L+ V GY
Sbjct: 393 GNRCRIVGSILLDGAEIDDEVTLENVIVGKFGKVGKKTKLTNCYVEGY 440
>|KLTH0D12012p (infer) YOR260W GCD1 Gamma subunit of the translation initiation
factor eIF2B the guanine-nucleotide exchange factor for
eIF2 activity subsequently regulated by phosphorylated
eIF2 first identified as a negative regulator of GCN4
expression : similar to uniprot|P09032 Saccharomyces
cerevisiae [Kluyveromyces thermotolerans]
Length = 499
Score = 53.5 bits (127), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 26/81 (32%), Positives = 45/81 (55%)
Query: 332 IGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNNVTINNSYIWDNAIIKDDSVVDHSIIAG 391
+G+ + +G S+ E TS+K SV+G+NC+IG I I D I D+ ++++++I
Sbjct: 366 VGADSVVGAECSISEKTSVKLSVLGKNCKIGKRCRIVGCVILDGVEIDDECILENAVIGN 425
Query: 392 NAEIGSGATLSPGTVIGYNVV 412
+IG L+ V G +V
Sbjct: 426 FTKIGKKCKLTNSYVEGSYIV 446
>|SACE0D04136p GDP-mannose pyrophosphorylase (mannose-1-phosphate
guanyltransferase), synthesizes GDP-mannose from GTP and
mannose-1-phosphate in cell wall biosynthesis; required
for normal cell wall structure [Saccharomyces
cerevisiae]
Length = 361
Score = 53.1 bits (126), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 32/130 (24%), Positives = 65/130 (50%), Gaps = 8/130 (6%)
Query: 17 FQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVNEVYLMCSSHADQI 76
+ ++L + TR PLT +P+ L+ N P+I + +E LANAGV ++ L + + +
Sbjct: 1 MKGLILVGGYGTRLRPLTLTVPKPLVEFGNRPMILHQIEALANAGVTDIVLAVNYRPEVM 60
Query: 77 QEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGD---FLLVSGDVVTNI 133
E ++K + + ++ S+E+ +G A ++ D F +++ DV+
Sbjct: 61 VETLKKYEKE-----YGVNITFSVETEPLGTAGPLKLAEDVLKKDNSPFFVLNSDVICEY 115
Query: 134 DFEKAMNAHK 143
F++ + HK
Sbjct: 116 PFKELADFHK 125
>|CAGL0K08888p (infer) YOR260w GCD1 : similar to uniprot|P09032 Saccharomyces
cerevisiae [Candida glabrata CBS 138]
Length = 534
Score = 51.6 bits (122), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 332 IGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNNVTINNSYIWDNAIIKDDSVVDHSIIAG 391
IG+ + +G N ++ E ++IK S I C+IGN + S + N ++DD ++++ II
Sbjct: 398 IGADSLVGGNVTILEKSNIKMSAIAGGCKIGNRCRVAGSILLANVELEDDVILENVIIGP 457
Query: 392 NAEIGSGATLSPGTVIGYNVVIGDGIHLSNNTRIVEKPIDRDDESFESSRSFDSEQED 449
A+IG + L+ V G V+ H R K I D +S ++ + ED
Sbjct: 458 GAKIGKKSKLTNCYVEGSYVLPARSTHKGETLR---KIILNTDTEMDSEVAYSTSDED 512
BLASTP 2.2.18 [Mar-02-2008]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
URL: http://www.genolevures.org/elt/DEHA/DEHA2G14322p/gl3_blastp/DEHA2G14322p.html