DEHA2F21604p_blastp.html 
BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= DEHA2F21604p (infer) YLR285W NNT1 Putative nicotinamide
N-methyltransferase : similar to uniprot|Q05874 Saccharomyces
cerevisiae [Debaryomyces hansenii CBS767]
         (254 letters)

Database: Genolevures3.aa 
           48,939 sequences; 23,992,848 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

|DEHA2F21604p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   523   e-149
|SACE0L13925p Putative nicotinamide N-methyltransferase, has a ro...   295   3e-80
|KLLA0C04708p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   281   6e-76
|SAKL0A07986p (infer) YLR285W NNT1 Putative nicotinamide N- methy...   276   1e-74
|ZYRO0D14542p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   272   2e-73
|KLTH0G15092p (infer) YLR285W NNT1 Putative nicotinamide N- methy...   271   6e-73
|CAGL0M09801p (infer) YLR285w : similar to uniprot|Q05874 Sacchar...   270   9e-73
|ERGO0G14674p Syntenic homolog of Saccharomyces cerevisiae YLR285...   249   2e-66
|YALI0A09636p (infer) YLR285w NNT1 nicotinamide N-methyltransfera...   219   2e-57


>|DEHA2F21604p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Debaryomyces hansenii CBS767]
          Length = 254

 Score =  523 bits (1346), Expect = e-149,   Method: Compositional matrix adjust.
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MSDDEFIDTGLFAEPEGFTPPPPPPHFAKYQRKNKTDPAELNLRLVGKSPLWGHLLWNAG 60
           MSDDEFIDTGLFAEPEGFTPPPPPPHFAKYQRKNKTDPAELNLRLVGKSPLWGHLLWNAG
Sbjct: 1   MSDDEFIDTGLFAEPEGFTPPPPPPHFAKYQRKNKTDPAELNLRLVGKSPLWGHLLWNAG 60

Query: 61  VFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLISNIQHNF 120
           VFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLISNIQHNF
Sbjct: 61  VFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLISNIQHNF 120

Query: 121 DHCQGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSDLVFNHTEHLKLLKT 180
           DHCQGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSDLVFNHTEHLKLLKT
Sbjct: 121 DHCQGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSDLVFNHTEHLKLLKT 180

Query: 181 CRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKIDLVTWKPMFEEDDESID 240
           CRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKIDLVTWKPMFEEDDESID
Sbjct: 181 CRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKIDLVTWKPMFEEDDESID 240

Query: 241 IRARVYSFFLVPQW 254
           IRARVYSFFLVPQW
Sbjct: 241 IRARVYSFFLVPQW 254


>|SACE0L13925p Putative nicotinamide N-methyltransferase, has a role in rDNA
           silencing and in lifespan determination [Saccharomyces
           cerevisiae]
          Length = 261

 Score =  295 bits (755), Expect = 3e-80,   Method: Compositional matrix adjust.
 Identities = 145/259 (55%), Positives = 185/259 (71%), Gaps = 9/259 (3%)

Query: 1   MSDDEFID--TGLFAEPEGFTPPPPPPHFAKYQR-----KNKTDPAELNLRLVGKSPLWG 53
           MSD E +    GLF EPE F PPPP PHFA+YQR     ++K+D  ++ LRLVG SPLWG
Sbjct: 1   MSDIESLGEAAGLFEEPEDFLPPPPKPHFAEYQRSHITKESKSDVKDIKLRLVGTSPLWG 60

Query: 54  HLLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLI 113
           HLLWNAG++TA++LD H  EL+ GK VLELGAAA LPS+IC +N    VV TDYPDPDL+
Sbjct: 61  HLLWNAGIYTANHLDSHP-ELIKGKTVLELGAAAALPSVICALNGAQMVVSTDYPDPDLM 119

Query: 114 SNIQHNFDHCQGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSDLVFNHTE 173
            NI +N       D +    +G+IWG D  PL+   EK   N  KFDL+ILSDLVFNHTE
Sbjct: 120 QNIDYNIKSNVPEDFNNVSTEGYIWGNDYSPLLAHIEKIGNNNGKFDLIILSDLVFNHTE 179

Query: 174 HLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCE-DFQFKAEKIDLVTWKPMF 232
           H KLL+T +D + + G+ LVVFSPHRPKLLE DLEFF   + +F    + I++V WKPMF
Sbjct: 180 HHKLLQTTKDLLAEKGQALVVFSPHRPKLLEKDLEFFELAKNEFHLVPQLIEMVNWKPMF 239

Query: 233 EEDDESIDIRARVYSFFLV 251
           +ED+E+I++R+RVY+++L 
Sbjct: 240 DEDEETIEVRSRVYAYYLT 258


>|KLLA0C04708p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Kluyveromyces lactis NRRL Y-1140]
          Length = 270

 Score =  281 bits (719), Expect = 6e-76,   Method: Compositional matrix adjust.
 Identities = 141/271 (52%), Positives = 187/271 (69%), Gaps = 25/271 (9%)

Query: 1   MSDDEFIDTG-LFAEPEGFTPPPPPPHFAKYQR-----KNKTDPAELNLRLVGKSPLWGH 54
           MSD E ++ G LFAEP  F  PPP PHFA Y R      + +   ++ LRLVG SPLWGH
Sbjct: 1   MSDIESLNGGDLFAEPSDFYKPPPEPHFATYTRDDVPESSTSQQKDIKLRLVGSSPLWGH 60

Query: 55  LLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLIS 114
           LLWNAG++TA ++D H +E V  K VLELGAA  LP++I G+    +VV TDYPD DLIS
Sbjct: 61  LLWNAGIYTAKHMDSHPEE-VQDKLVLELGAAGALPTIIAGLLGARKVVSTDYPDADLIS 119

Query: 115 NIQHNFDH---------------CQGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKF 159
           NIQ+N DH                + +   K VV+G+IWG D +P++   +   Q++ KF
Sbjct: 120 NIQYNVDHNIYGGEELFKDEEKRSKQMANRKVVVEGYIWGNDYEPIL---KHLPQDQQKF 176

Query: 160 DLVILSDLVFNHTEHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFK 219
           DL+ILSDLVFNHTEH KL KT +D +++NGK LVVFSPHRP LLENDL FF+ CE+F  K
Sbjct: 177 DLIILSDLVFNHTEHAKLFKTTKDLLRENGKALVVFSPHRPWLLENDLAFFKDCEEFGLK 236

Query: 220 AEKIDLVTWKPMFEEDDESIDIRARVYSFFL 250
           ++ I+L  WKPMF+ED+E+++IR+ +Y+++L
Sbjct: 237 SDLIELTHWKPMFDEDEETVEIRSSIYAYYL 267


>|SAKL0A07986p (infer) YLR285W NNT1 Putative nicotinamide N- methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           highly similar to uniprot|Q05874 Saccharomyces
           cerevisiae [Lachancea kluyveri]
          Length = 270

 Score =  276 bits (707), Expect = 1e-74,   Method: Compositional matrix adjust.
 Identities = 143/273 (52%), Positives = 182/273 (66%), Gaps = 27/273 (9%)

Query: 1   MSDDE-FIDTGLFAEPEGFTPPPPPPHFAKYQRKNKTDPA-----ELNLRLVGKSPLWGH 54
           MSD E  I+  LF EPE F  PPP PHFA Y+R   +  +     E+ LRLVG SPLWGH
Sbjct: 1   MSDTESLIEGSLFEEPEDFNKPPPQPHFATYERTTVSPQSNSLVKEVKLRLVGSSPLWGH 60

Query: 55  LLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLIS 114
           LLWNAG++T  +LD++   LV  K VLELGAA  LPS+ICG+   ++VV TD+PD DL+ 
Sbjct: 61  LLWNAGIYTGRHLDENIG-LVKDKTVLELGAAGALPSIICGLIGASKVVVTDFPDADLLQ 119

Query: 115 NIQHNFDHC----------------QGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDK 158
           NIQ+N DH                 Q L     VV+G+IWG D +PL+    K I +  K
Sbjct: 120 NIQYNVDHQIYQGNELPADGDDARDQELQRRDVVVEGYIWGNDYEPLV----KHIGSGKK 175

Query: 159 FDLVILSDLVFNHTEHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQF 218
           FDL+ILSDLVFNH+EH KLL T +D + K+GK LVVFSPHRP LL  DL+FF T ++   
Sbjct: 176 FDLIILSDLVFNHSEHAKLLNTTKDLLAKDGKALVVFSPHRPWLLNADLQFFETAKEHGL 235

Query: 219 KAEKIDLVTWKPMFEEDDESIDIRARVYSFFLV 251
           K EKI++V WKPMFEED+E+ +IR+RVY+++L 
Sbjct: 236 KPEKIEMVNWKPMFEEDEETAEIRSRVYAYYLT 268


>|ZYRO0D14542p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Zygosaccharomyces rouxii]
          Length = 263

 Score =  272 bits (696), Expect = 2e-73,   Method: Compositional matrix adjust.
 Identities = 137/265 (51%), Positives = 182/265 (68%), Gaps = 20/265 (7%)

Query: 1   MSDDEFIDT-GLFAEPEGFTPPPPPPHFAKYQRK-----NKTDPAELNLRLVGKSPLWGH 54
           MSD+E     G+F EP  F PPPP  HFA Y+R+     + +   ++ LRLVGKSPLWGH
Sbjct: 1   MSDNELDGAFGVFEEPTDFLPPPPEAHFADYEREYVSKESDSQNKKVQLRLVGKSPLWGH 60

Query: 55  LLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLIS 114
           +LWNAG++TA +LDKH   LV GK+VLELGAAA LP+++CG+   N+VV TDYP+P+LI 
Sbjct: 61  MLWNAGIYTAKHLDKHPG-LVKGKNVLELGAAAALPTVVCGLIGANKVVSTDYPEPELIQ 119

Query: 115 NIQHNFDH--------CQGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSD 166
           NIQ+N DH         Q  +  K VV+G+IWG + +P++  +        KFDL+ILSD
Sbjct: 120 NIQYNVDHELYGGKPFSQDSNDRKVVVEGYIWGNEYEPILSHT-----GGSKFDLIILSD 174

Query: 167 LVFNHTEHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKIDLV 226
            VFNHTEH KLL+  +D +  +GK LVVFSPHRP+LL+ DL FF T ++F    E IDLV
Sbjct: 175 CVFNHTEHRKLLRCIKDLLANDGKALVVFSPHRPRLLDVDLSFFETAKEFGLAPEFIDLV 234

Query: 227 TWKPMFEEDDESIDIRARVYSFFLV 251
            W PMF+ED  + +IR+RVY+++L 
Sbjct: 235 KWHPMFDEDPSTAEIRSRVYAYYLT 259


>|KLTH0G15092p (infer) YLR285W NNT1 Putative nicotinamide N- methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Kluyveromyces thermotolerans]
          Length = 266

 Score =  271 bits (693), Expect = 6e-73,   Method: Compositional matrix adjust.
 Identities = 142/268 (52%), Positives = 180/268 (67%), Gaps = 21/268 (7%)

Query: 1   MSDDE-FIDTGLFAEPEGFTPPPPPPHFAKYQRK-----NKTDPAELNLRLVGKSPLWGH 54
           MSD E FI   +FAEPEG+    P  HFA+Y R+     +K+   E+ LRLVG SPLWGH
Sbjct: 1   MSDTESFIQGDIFAEPEGYFQAEPEAHFAEYVREQVPSASKSQKKEVRLRLVGSSPLWGH 60

Query: 55  LLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLIS 114
           LLWNAG++TA++LDK  D LV  + VLELGAA  LPS++ G+    + V TDYPD DL+ 
Sbjct: 61  LLWNAGIYTANHLDKFPD-LVKDRCVLELGAAGALPSVVAGMIGAKKCVVTDYPDADLLQ 119

Query: 115 NIQHNFDH-----------CQGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKFDLVI 163
           NIQ+N DH             G      VV+G+IWG D  PL+           KFDLVI
Sbjct: 120 NIQYNVDHEVFDGEALPSDGAGASERNVVVEGYIWGNDYAPLVSHLPC---GTTKFDLVI 176

Query: 164 LSDLVFNHTEHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKI 223
           LSDLVFNHTEHLKLL+T +D + ++GK LVVFSPHRP LL +DL+FF T +DF    EKI
Sbjct: 177 LSDLVFNHTEHLKLLQTTKDLLAQDGKALVVFSPHRPWLLNDDLQFFETAKDFALVPEKI 236

Query: 224 DLVTWKPMFEEDDESIDIRARVYSFFLV 251
           ++V WKPMFEED+E+ +IR+RVY+++L 
Sbjct: 237 EMVNWKPMFEEDEETSEIRSRVYAYYLT 264


>|CAGL0M09801p (infer) YLR285w : similar to uniprot|Q05874 Saccharomyces
           cerevisiae [Candida glabrata CBS 138]
          Length = 256

 Score =  270 bits (691), Expect = 9e-73,   Method: Compositional matrix adjust.
 Identities = 135/259 (52%), Positives = 182/259 (70%), Gaps = 13/259 (5%)

Query: 1   MSDDEFID--TGLFAEPEGFTPPPPPPHFAKYQRK-----NKTDPAELNLRLVGKSPLWG 53
           MSD E ++   GLF EPE F P  P  H+A Y+R      +K+    L L+LVG SPLWG
Sbjct: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60

Query: 54  HLLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLI 113
           HLLWNAG++TA +LDK+  ELV+ K+VLELGAA+ LPSL+ G+    R V TDYPD DL+
Sbjct: 61  HLLWNAGIYTARHLDKYP-ELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLM 119

Query: 114 SNIQHNFDHCQGLDLSKTV-VKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSDLVFNHT 172
           +NIQ+N +     +L + V V+G+IWG +  PL       +  + KFDL+ILSDLVFNH 
Sbjct: 120 ANIQYNVNTIIPDELKENVRVEGYIWGNEYDPLT----IHLDGDKKFDLIILSDLVFNHN 175

Query: 173 EHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKIDLVTWKPMF 232
           +H KLL+T +D +  NGK LVVFSPHRP LLE DL+FF TC+++    EKI++V WKPMF
Sbjct: 176 QHDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEKIEMVNWKPMF 235

Query: 233 EEDDESIDIRARVYSFFLV 251
           EED+E+ ++R+RVY++++ 
Sbjct: 236 EEDEETAEVRSRVYAYYMT 254


>|ERGO0G14674p Syntenic homolog of Saccharomyces cerevisiae YLR285W (NNT1)
           [Eremothecium gossypii]
          Length = 265

 Score =  249 bits (636), Expect = 2e-66,   Method: Compositional matrix adjust.
 Identities = 125/259 (48%), Positives = 166/259 (64%), Gaps = 14/259 (5%)

Query: 3   DDEFIDTGLFAEPEGFTPPPPPPHFAKYQR-----KNKTDPAELNLRLVGKSPLWGHLLW 57
           D  +  T LF EP+GF   P   HFA+Y+R     ++     ++ +RLVG SPLWGHLLW
Sbjct: 8   DSLYGATELFGEPDGFYEKPAESHFAEYERSAVPAQSARRDTQVRIRLVGSSPLWGHLLW 67

Query: 58  NAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLISNIQ 117
           N+ ++TA +LD H +++V G+ VLELGAA  LPSL+ G+    +VV TDYPD DL+ NIQ
Sbjct: 68  NSAIYTARHLDAHPEQVV-GRCVLELGAAGALPSLVAGLLGARQVVATDYPDADLVGNIQ 126

Query: 118 HNFDHC-----QGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSDLVFNHT 172
           +N DH         +     V+G+IWG D  PL          +  FDLV+LSDLVFNHT
Sbjct: 127 YNVDHVIYGGKPPTEAPHVAVEGYIWGNDYGPLRRHLPP---GQTGFDLVLLSDLVFNHT 183

Query: 173 EHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKIDLVTWKPMF 232
           EH KLL+T RD +   G+ LVVFSPHRP LLE DL+FF T  ++  +AE I+ VTW PMF
Sbjct: 184 EHHKLLQTTRDLLAPAGRALVVFSPHRPWLLEKDLQFFETAAEYGLRAELIEQVTWAPMF 243

Query: 233 EEDDESIDIRARVYSFFLV 251
            +D    ++RARVY+++L 
Sbjct: 244 ADDPGPAEVRARVYAYYLT 262


>|YALI0A09636p (infer) YLR285w NNT1 nicotinamide N-methyltransferase : similar to
           uniprot|Q05874 Saccharomyces cerevisiae [Yarrowia
           lipolytica CLIB122]
          Length = 273

 Score =  219 bits (558), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 120/275 (43%), Positives = 166/275 (60%), Gaps = 29/275 (10%)

Query: 1   MSD-DEFIDTGLFAEPEGFTPPPPPPHFAKYQRKNK-------TDPAELNLRLVGKSPLW 52
           MSD ++    GLF EP+ F  P   P    Y R+ K        +P   NLRL  K+PLW
Sbjct: 1   MSDIEDLASGGLFDEPKDFYKPEEQPGSDSYARQEKHVAASEYKEPTNFNLRLTAKNPLW 60

Query: 53  GHLLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDL 112
           GHLLWNAG  T+DYLD+H+ ELV GK V+E GA AGLPSL+C      +VV TDYPD DL
Sbjct: 61  GHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDADL 120

Query: 113 ISNIQHNFDHCQG---------------LDLSKTVVKGFIWGADAKPLMDDSEKEIQNED 157
           + N+++N D  +                 D+S   V+GFIWG DA  L+     E+    
Sbjct: 121 LYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASELI-----EMSGGT 175

Query: 158 KFDLVILSDLVFNHTEHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCED-F 216
            +DLVILSD+VFNH+EH KL+++ ++ +   GK  VVF+PHR KL   DL+FFR  +D  
Sbjct: 176 GYDLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEA 235

Query: 217 QFKAEKIDLVTWKPMFEEDDESIDIRARVYSFFLV 251
            F++EK+  + + PMFEE++E+ ++R+ V+ + L 
Sbjct: 236 GFESEKLFELKYYPMFEEEEETKELRSMVFGYMLT 270



BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.