DEHA2C05984p_blastp.html 
BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= DEHA2C05984p (infer) YBL098w BNA4 Kynurenine 3-mono oxygenase :
similar to uniprot|P38169 Saccharomyces cerevisiae [Debaryomyces
hansenii CBS767]
         (473 letters)

Database: Genolevures3.aa 
           48,939 sequences; 23,992,848 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

|DEHA2C05984p (infer) YBL098w BNA4 Kynurenine 3-mono oxygenase : ...   987   0.0  
|SAKL0F13332p (infer) YBL098W BNA4 Kynurenine 3-mono oxygenase re...   501   e-141
|KLTH0C05786p (infer) YBL098W BNA4 Kynurenine 3-mono oxygenase re...   485   e-137
|ZYRO0F13002p (infer) YBL098W BNA4 Kynurenine 3-mono oxygenase re...   476   e-134
|ERGO0G02178p Syntenic homolog of Saccharomyces cerevisiae YBL098...   454   e-127
|YALI0D09867p (infer) YBL098w related to kynurenine 3-monooxygena...   447   e-125
|SACE0B00440p Kynurenine 3-mono oxygenase, required for the de no...   427   e-119


>|DEHA2C05984p (infer) YBL098w BNA4 Kynurenine 3-mono oxygenase : similar to
           uniprot|P38169 Saccharomyces cerevisiae [Debaryomyces
           hansenii CBS767]
          Length = 473

 Score =  987 bits (2551), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 473/473 (100%), Positives = 473/473 (100%)

Query: 1   MASAKEDNKHQGVGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPKKVTNEKNLRSINLA 60
           MASAKEDNKHQGVGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPKKVTNEKNLRSINLA
Sbjct: 1   MASAKEDNKHQGVGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPKKVTNEKNLRSINLA 60

Query: 61  VSDRGIRTLKYVDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFL 120
           VSDRGIRTLKYVDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFL
Sbjct: 61  VSDRGIRTLKYVDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFL 120

Query: 121 NDYLLDEIRHSDINVHFNHKLIRLDDLSSEEKSPKLTFLDTSESNESTMKSYEFDYVIGA 180
           NDYLLDEIRHSDINVHFNHKLIRLDDLSSEEKSPKLTFLDTSESNESTMKSYEFDYVIGA
Sbjct: 121 NDYLLDEIRHSDINVHFNHKLIRLDDLSSEEKSPKLTFLDTSESNESTMKSYEFDYVIGA 180

Query: 181 DGAHSQFRYQLQKSMRMNISQEYIDMQYLELSIPPNTTGDSKFHIDPNHLHIWPRHEFML 240
           DGAHSQFRYQLQKSMRMNISQEYIDMQYLELSIPPNTTGDSKFHIDPNHLHIWPRHEFML
Sbjct: 181 DGAHSQFRYQLQKSMRMNISQEYIDMQYLELSIPPNTTGDSKFHIDPNHLHIWPRHEFML 240

Query: 241 IALANEDGSFTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPR 300
           IALANEDGSFTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPR
Sbjct: 241 IALANEDGSFTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPR 300

Query: 301 GSLMQVNAYPYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSES 360
           GSLMQVNAYPYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSES
Sbjct: 301 GSLMQVNAYPYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSES 360

Query: 361 FRQYSVLRAEDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYT 420
           FRQYSVLRAEDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYT
Sbjct: 361 FRQYSVLRAEDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYT 420

Query: 421 MISFRGDIPYSKAIKIEKRQTKILNAIEVGTLTGFILFGAAKLAQHYHKLSNK 473
           MISFRGDIPYSKAIKIEKRQTKILNAIEVGTLTGFILFGAAKLAQHYHKLSNK
Sbjct: 421 MISFRGDIPYSKAIKIEKRQTKILNAIEVGTLTGFILFGAAKLAQHYHKLSNK 473


>|SAKL0F13332p (infer) YBL098W BNA4 Kynurenine 3-mono oxygenase required for
           biosynthesis of nicotinic acid from tryptophan via
           kynurenine pathway : similar to uniprot|P38169
           Saccharomyces cerevisiae [Lachancea kluyveri]
          Length = 462

 Score =  501 bits (1289), Expect = e-141,   Method: Compositional matrix adjust.
 Identities = 251/464 (54%), Positives = 322/464 (69%), Gaps = 31/464 (6%)

Query: 11  QGVGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPKKV-TNEKNLRSINLAVSDRGIRTL 69
           + V +VGAGLVGCL ++A A +G+ V+LF+ R DP+K  T ++NLRSINLA+SDRGI +L
Sbjct: 3   ESVAVVGAGLVGCLASIALAKRGYQVSLFDYREDPRKASTTDRNLRSINLAISDRGITSL 62

Query: 70  KYVDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFLNDYLLDEI- 128
           KY+D E+ +RVL+ +IPM GRMIHDL G  QESQ YGLFGE INSIDR+ LN+ LL E+ 
Sbjct: 63  KYIDEEIGERVLKDIIPMKGRMIHDLQGN-QESQIYGLFGECINSIDRAVLNNSLLGEVD 121

Query: 129 RHSDINVHFNHKLIRLDDLSSEEKSPKLTFLDTSE----SNESTMKSYEFDYVIGADGAH 184
           +  ++ V + HKL+R+             F D+ +    S E  ++   FD+V+G DGA+
Sbjct: 122 KLKNVQVEYAHKLVRI------------KFSDSVQTCLFSTEDGVRELGFDFVVGCDGAY 169

Query: 185 SQFRYQLQKSMRMNISQEYIDMQYLELSIPP----NTTGDSKFHIDPNHLHIWPRHEFML 240
           S  RYQ+Q+ MRM+ +QEYID  Y+EL IPP    N     KF I PNHLHIWPRH +ML
Sbjct: 170 STTRYQMQREMRMDFAQEYIDCCYIELYIPPAADYNKEFKGKFSICPNHLHIWPRHNYML 229

Query: 241 IALANEDGSFTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPR 300
           IALAN DGSFTSTFF PWS++E    S DK   FFK  FPDA +L+G +   YAFEN P+
Sbjct: 230 IALANVDGSFTSTFFGPWSLVERL-DSKDKIESFFKEEFPDAVELIGLENAVYAFENHPK 288

Query: 301 GSLMQVNAYPYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSES 360
           G+LM V   PYH P G+ +I+GDAAHSMVPFYGQGMNCGFED++VLM L+DK  G+   +
Sbjct: 289 GALMCVECKPYHVPGGKGIILGDAAHSMVPFYGQGMNCGFEDVKVLMRLLDKYKGDRQRA 348

Query: 361 FRQYSVLRAEDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYT 420
           F +YS  R EDL  I  LA +NY EMS KVT+  +L RKK+D MLG+      +W+P+YT
Sbjct: 349 FDEYSHSRHEDLVAIIDLAKNNYKEMSHKVTSKLFLLRKKLDYMLGKTLKD--RWLPLYT 406

Query: 421 MISFRGDIPYSKAIKIEKRQTKILN-----AIEVGTLTGFILFG 459
           M+SFR DIPY KAI+IEKRQ ++L       I   +L+GF + G
Sbjct: 407 MVSFRADIPYHKAIEIEKRQQRVLRYLQAIIIAAVSLSGFKVAG 450


>|KLTH0C05786p (infer) YBL098W BNA4 Kynurenine 3-mono oxygenase required for
           biosynthesis of nicotinic acid from tryptophan via
           kynurenine pathway : similar to uniprot|P38169
           Saccharomyces cerevisiae [Kluyveromyces thermotolerans]
          Length = 463

 Score =  485 bits (1249), Expect = e-137,   Method: Compositional matrix adjust.
 Identities = 245/453 (54%), Positives = 316/453 (69%), Gaps = 20/453 (4%)

Query: 11  QGVGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPK-KVTNEKNLRSINLAVSDRGIRTL 69
           + V ++GAGLVGCL A+A A +G+ VTLF+ R DP+   T ++NLRSINLA+S RGI +L
Sbjct: 3   ETVAVIGAGLVGCLAAVALAKRGYEVTLFDYRLDPRLATTQDRNLRSINLAISARGITSL 62

Query: 70  KYVDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFLNDYLLDEIR 129
           +YVD  ++ RVL+ +IPM GRMIH+L G  QE+Q YGLFGE INSIDR  LN+ LLDE+ 
Sbjct: 63  EYVDKGISKRVLKDIIPMQGRMIHNLRG-HQEAQNYGLFGECINSIDRGVLNNSLLDEVD 121

Query: 130 H-SDINVHFNHKLIRLDDLSSEEKSPKLTFLDTSESNESTMKSYEFDYVIGADGAHSQFR 188
           +  ++ + F HKL ++    + +++   T      +  S  K Y FD+V+G DGA+S  R
Sbjct: 122 NLQNVALKFGHKLSQIKFTPNAKQTCVFT-----TNAASAAKEYAFDFVLGCDGAYSSTR 176

Query: 189 YQLQKSMRMNISQEYIDMQYLELSIPP----NTTGDSKFHIDPNHLHIWPRHEFMLIALA 244
            Q+Q+ +RM+ SQEYID  Y+EL +PP    N   + KF I PNHLHIWPR  +MLIALA
Sbjct: 177 SQMQRELRMDFSQEYIDCCYIELYVPPAKEHNPKFNGKFAISPNHLHIWPRGNYMLIALA 236

Query: 245 NEDGSFTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPRGSLM 304
           N DGSFTSTFF PWS++E   T S K  DF   NFPDA +++G K+   AFEN PRG+LM
Sbjct: 237 NGDGSFTSTFFGPWSLVEGLDTRS-KIQDFLTNNFPDAVEIIGLKQAVDAFENHPRGALM 295

Query: 305 QVNAYPYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSESFRQY 364
            V   PYH   GRA+I+GDAAHSMVPFYGQGMNCGFED+RVLM+L+DK++G  + +F +Y
Sbjct: 296 CVECSPYHLSQGRAIILGDAAHSMVPFYGQGMNCGFEDVRVLMQLLDKHSGNRAAAFEEY 355

Query: 365 SVLRAEDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYTMISF 424
           S  R  DL +I KLA +NY EMS  V +  YL RKK+D +LGR      +W+P+YTM+SF
Sbjct: 356 SSKRHTDLVSIIKLAKNNYKEMSHGVISNLYLLRKKLDTLLGRVLKD--RWLPLYTMVSF 413

Query: 425 RGDIPYSKAIKIEKRQTKILNAIEVGTLTGFIL 457
           R DIPY KAI+IE+RQ KIL       L  FIL
Sbjct: 414 RADIPYHKAIQIEQRQKKIL-----AYLQAFIL 441


>|ZYRO0F13002p (infer) YBL098W BNA4 Kynurenine 3-mono oxygenase required for
           biosynthesis of nicotinic acid from tryptophan via
           kynurenine pathway : similar to uniprot|P38169
           Saccharomyces cerevisiae [Zygosaccharomyces rouxii]
          Length = 464

 Score =  476 bits (1224), Expect = e-134,   Method: Compositional matrix adjust.
 Identities = 238/460 (51%), Positives = 323/460 (70%), Gaps = 16/460 (3%)

Query: 13  VGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPKKV-TNEKNLRSINLAVSDRGIRTLKY 71
           V +VGAGLVGCL +LAF  +G+ V++++ R DP+ V T +KNLRSINLA+S RGI +LK 
Sbjct: 5   VIVVGAGLVGCLASLAFHKRGYQVSVYDYRLDPRDVSTQDKNLRSINLAISARGIESLKS 64

Query: 72  VDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFLNDYLLDEIRHS 131
           VD ++A RVL  VIPM GRMIHDL G +QESQ YGLFGE INSIDR+ LN++LLDE+   
Sbjct: 65  VDEQIAQRVLRDVIPMKGRMIHDLQG-EQESQIYGLFGECINSIDRAVLNNFLLDELDRC 123

Query: 132 DINVHFNHKLIRLDDLSSEEKSPKLTFLDTSESNESTMKSYEFDYVIGADGAHSQFRYQL 191
           +I+V F +KL++     ++    + T + +    +  +++ E D+++G DGA S  RYQ+
Sbjct: 124 NIDVKFGYKLVK-----AKFGDQRQTCIFSQMGQDGVIETIECDFIVGCDGAFSSTRYQM 178

Query: 192 QKSMRMNISQEYIDMQYLELSIPPNTTGDSKFH----IDPNHLHIWPRHEFMLIALANED 247
           Q++MRM+ SQEYID  Y+EL IP     + KF+    I P+HLHIWPRH +MLIALAN D
Sbjct: 179 QRAMRMDYSQEYIDCCYIELYIPKTEKFNEKFNGNFAIAPDHLHIWPRHNYMLIALANGD 238

Query: 248 GSFTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPRGSLMQVN 307
           GSFTSTFF PWS++ES   S +K   F   NFPDA +LMG  +  + F N P+G+LM V 
Sbjct: 239 GSFTSTFFGPWSLVESLIESKEKTRKFLLENFPDAMQLMGIDEAVHKFINYPKGALMCVE 298

Query: 308 AYPYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSESFRQYSVL 367
             PYH   G+A+I+GDAAHSMVPFYGQGMNCGFED++VLMEL+D++ G+ + +F++YS  
Sbjct: 299 CNPYHVNGGKAIILGDAAHSMVPFYGQGMNCGFEDVKVLMELLDQSKGDRNIAFQRYSET 358

Query: 368 RAEDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYTMISFRGD 427
           R +DL  I +LA +NY EMS  VT+  +L +K++D  LGR      +W+P+YTM+SFR D
Sbjct: 359 RHKDLVAIIELAKNNYKEMSHDVTSTLFLIKKQLDGALGRLLKN--KWLPLYTMVSFRAD 416

Query: 428 IPYSKAIKIEKRQTKILNA-IEVGTLTGFIL--FGAAKLA 464
           +PY +A++I  RQ  ILN  + V   TG IL   G ++L 
Sbjct: 417 VPYHRAVEISNRQKVILNQLLGVMLTTGTILTALGLSRLG 456


>|ERGO0G02178p Syntenic homolog of Saccharomyces cerevisiae YBL098W (BNA4)
           [Eremothecium gossypii]
          Length = 466

 Score =  454 bits (1167), Expect = e-127,   Method: Compositional matrix adjust.
 Identities = 225/451 (49%), Positives = 305/451 (67%), Gaps = 17/451 (3%)

Query: 9   KHQGVGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPK-KVTNEKNLRSINLAVSDRGIR 67
           K + V ++GAGLVGCL ALAFA KG+ V+LF+ R DP+   T ++NLRSINLA+S RGI 
Sbjct: 4   KGESVAVIGAGLVGCLAALAFAKKGYEVSLFDYRSDPRLATTTDRNLRSINLAISARGIE 63

Query: 68  TLKYVDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFLNDYLLDE 127
            LK VD E+A RVL  ++PM GRMIH+L+G KQE Q YGLFGES+NSIDR  LN+ LLDE
Sbjct: 64  GLKAVDDELAARVLRDMLPMHGRMIHNLAG-KQEPQEYGLFGESVNSIDRGVLNNALLDE 122

Query: 128 IRHSD-INVHFNHKLIRLDDLSSEEKSPKLTFLDTSESNESTMKSYEFDYVIGADGAHSQ 186
           +   + I   F HKL++ +   +   + +L F     + E      EFD+V+G DGA+S 
Sbjct: 123 VSAQEHIQAQFGHKLVKAN--FNHGATQQLLF-----AVEGKTVQLEFDFVVGCDGAYST 175

Query: 187 FRYQLQKSMRMNISQEYIDMQYLELSIPPNTTGDSKF----HIDPNHLHIWPRHEFMLIA 242
            R Q+Q+  RM+ SQEY+D  YLEL IPP      +F     I P HLHIWPRH FMLIA
Sbjct: 176 TRQQMQRFDRMDFSQEYMDCFYLELYIPPTPEFSERFGGPFAISPQHLHIWPRHNFMLIA 235

Query: 243 LANEDGSFTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPRGS 302
           L N+DGSFTSTFF PWS+++   T  ++   F   NF DA +L+G      AF+   +G+
Sbjct: 236 LPNKDGSFTSTFFGPWSLLDRLDTR-EQLAAFLTTNFADAMELIGLDNAIRAFQENTKGA 294

Query: 303 LMQVNAYPYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSESFR 362
           LM V   PYH P G+A+++GDAAH+MVPFYGQGMNCGFED+RVLM L+D   G+ + +F 
Sbjct: 295 LMCVECRPYHLPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRVLMGLLDDYAGDRTAAFA 354

Query: 363 QYSVLRAEDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYTMI 422
           +Y+  R  DL +I +LA +NY +MS  V + W+  ++ ++N+LGR   G   W+P+YTM+
Sbjct: 355 KYTASRHRDLVSIIQLAKNNYRDMSHNVVSSWHRAKRSLNNVLGRTFRG--TWLPLYTMV 412

Query: 423 SFRGDIPYSKAIKIEKRQTKILNAIEVGTLT 453
           SFR DIPY KA+++++RQ  IL+ ++   L+
Sbjct: 413 SFRADIPYHKAVEVDRRQAAILSLVQSALLS 443


>|YALI0D09867p (infer) YBL098w related to kynurenine 3-monooxygenase : similar to
           uniprot|P38169 Saccharomyces cerevisiae [Yarrowia
           lipolytica CLIB122]
          Length = 463

 Score =  447 bits (1150), Expect = e-125,   Method: Compositional matrix adjust.
 Identities = 234/452 (51%), Positives = 303/452 (67%), Gaps = 11/452 (2%)

Query: 13  VGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPKKVTNEKN--LRSINLAVSDRGIRTLK 70
           V +VGAGLVGCL ALAFA +G  V L++ RPD +     KN  LRSINLAVS RGI  L+
Sbjct: 4   VTVVGAGLVGCLAALAFADRGHKVALYDARPDLRSEAELKNASLRSINLAVSARGIEALR 63

Query: 71  YVDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFLNDYLLDEIR- 129
            VD++MA+RVL  +IPM GRMIHDL G  Q +QAYGL+GE INSIDR+ LN  +LD I  
Sbjct: 64  SVDTKMAERVLADIIPMYGRMIHDLQGG-QHAQAYGLWGECINSIDRAQLNRTMLDVIED 122

Query: 130 HSDINVHFNHKLIRLDDLSSEEKSPKLTFLDTSESNESTMKSYEFDYVIGADGAHSQFRY 189
           +++I     HKL  +     ++K  + T   T E+ E   +  E DY+IGADGA S+ R 
Sbjct: 123 NANITFFPEHKLTNISLSRKDKKYQRPT--STFETKEGEERVVESDYIIGADGAFSKTRD 180

Query: 190 QLQKSMRMNISQEYIDMQYLELSIPPNTTGDSKFHIDPNHLHIWPRHEFMLIALANEDGS 249
           +LQ+ +RMN +Q+YID  YLEL IP    G   F I PNHLHIWPRH++MLIALAN DGS
Sbjct: 181 RLQRYVRMNYAQQYIDCVYLELKIP-KADGPDPFSISPNHLHIWPRHKYMLIALANGDGS 239

Query: 250 FTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPRGSLMQVNAY 309
           FTST F+P +++E    S + FI FFK  FPDA++LMGE ++  ++EN PR  L+ +   
Sbjct: 240 FTSTLFAPPALMEQVCESQNTFISFFKEQFPDAYELMGESQILESYENNPRSPLVSLKCS 299

Query: 310 PYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSESFRQYSVLRA 369
           PY N  G  L++GDAAH MVPFYGQGMN GFEDIRVLME++D+    V E+F  Y+  R 
Sbjct: 300 PY-NHKGECLLVGDAAHCMVPFYGQGMNAGFEDIRVLMEILDEKKWNVEEAFNTYTERRH 358

Query: 370 EDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYTMISFRGDIP 429
           +DL  I  LA+ NY EMS  V ++ YL RKK+D +LGR  +    W+P+Y+M+SFR DIP
Sbjct: 359 KDLVAIVDLAMRNYVEMSHSVVSLPYLIRKKVDGVLGRVFSS--AWVPLYSMVSFRADIP 416

Query: 430 YSKAIKIEKRQTKIL-NAIEVGTLTGFILFGA 460
           YSKA+    RQ +I+ N +   +  G +  GA
Sbjct: 417 YSKALSRSARQDRIIGNIVNWTSFAGLVGMGA 448


>|SACE0B00440p Kynurenine 3-mono oxygenase, required for the de novo biosynthesis
           of NAD from tryptophan via kynurenine; expression
           regulated by Hst1p; putative therapeutic target for
           Huntington disease [Saccharomyces cerevisiae]
          Length = 460

 Score =  427 bits (1097), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 223/460 (48%), Positives = 309/460 (67%), Gaps = 18/460 (3%)

Query: 11  QGVGIVGAGLVGCLTALAFAAKGFSVTLFELRPDPK-KVTNEKNLRSINLAVSDRGIRTL 69
           + V I+GAGLVGCL ALAF+ +G++VTL++ R DP+   T  KNL+SINLA+S RGI  L
Sbjct: 3   ESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGIDAL 62

Query: 70  KYVDSEMADRVLEHVIPMTGRMIHDLSGTKQESQAYGLFGESINSIDRSFLNDYLLDEIR 129
           K +D +  + +L+ +IPM GRMIHDL G +QESQ YGL GE+INSI+RS LN+ LLDE+ 
Sbjct: 63  KSIDPDACEHILQDMIPMKGRMIHDLKG-RQESQLYGLHGEAINSINRSVLNNSLLDELE 121

Query: 130 HSDINVHFNHKLIRLDDLSSEEKSPKLTFLDTSESNESTMKSYEFDYVIGADGAHSQFRY 189
            S   + F HKL++++   +++K  ++      E +  T  + ++D+VIG DGA+S  R 
Sbjct: 122 KSTTELKFGHKLVKIE--WTDDK--QICHFAIGE-DLKTPHTEKYDFVIGCDGAYSATRS 176

Query: 190 QLQKSMRMNISQEYIDMQYLELSIPP------NTTGDSKFHIDPNHLHIWPRHEFMLIAL 243
           Q+Q+ + M+ SQEY++++Y+EL IPP      N  G+  F I P+HLHIWPRH+FMLIAL
Sbjct: 177 QMQRKVEMDFSQEYMNLRYIELYIPPTEEFKPNYGGN--FAIAPDHLHIWPRHKFMLIAL 234

Query: 244 ANEDGSFTSTFFSPWSVIESFGTSSDKFIDFFKYNFPDAFKLMGEKKLRYAFENQPRGSL 303
           AN DGSFTSTFF     I    TS  +  +F   NFPD   +M        F   P+ SL
Sbjct: 235 ANSDGSFTSTFFGSKDQISDLITSKSRVREFLIENFPDIINIMDLDDAVKRFITYPKESL 294

Query: 304 MQVNAYPYHNPNGRALIIGDAAHSMVPFYGQGMNCGFEDIRVLMELIDKNNGEVSESFRQ 363
           + VN  PY  P G+A+++GDAAH+MVPFYGQGMNCGFED+R+LM L+ K++G+ S +F +
Sbjct: 295 VCVNCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILMALLKKHSGDRSRAFTE 354

Query: 364 YSVLRAEDLQTISKLALDNYHEMSSKVTNVWYLFRKKIDNMLGRYGNGLFQWIPMYTMIS 423
           Y+  R +DL +I++LA  NY EMS  VT+  +L RKK+D +         +WIP+YTMIS
Sbjct: 355 YTQTRHKDLVSITELAKRNYKEMSHDVTSKRFLLRKKLDALFSIIMKD--KWIPLYTMIS 412

Query: 424 FRGDIPYSKAIKIEKRQTKILNAIEVGTLTGFILFGAAKL 463
           FR DI YS+A++   +QT+IL  +E  TL G +  G  KL
Sbjct: 413 FRSDISYSRALERAGKQTRILKFLESLTL-GMLSIGGYKL 451



BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.