CAGL0M11506p_blastp.html
BLASTP 2.2.18 [Mar-02-2008]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= CAGL0M11506p (infer) YLR100w ERG27 3-keto sterol reductase :
highly similar to uniprot|Q12452 Saccharomyces cerevisiae [Candida
glabrata CBS 138]
(348 letters)
Database: UniProtSPTR-2008-09-12
6,610,332 sequences; 2,152,114,156 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6FIV3|ERG27_CANGA 3-keto-steroid reductase OS=Candida glabra... 718 0.0
tr|A7A105|A7A105_YEAS7 3-keto sterol reductase OS=Saccharomyces ... 544 e-153
sp|Q12452|ERG27_YEAST 3-keto-steroid reductase OS=Saccharomyces ... 543 e-153
tr|B3LT69|B3LT69_YEAST 3-keto sterol reductase OS=Saccharomyces ... 543 e-153
sp|Q6CJC2|ERG27_KLULA 3-keto-steroid reductase OS=Kluyveromyces ... 514 e-144
tr|A7TJ17|A7TJ17_VANPO Putative uncharacterized protein OS=Vande... 510 e-143
sp|Q74ZZ0|ERG27_ASHGO 3-keto-steroid reductase OS=Ashbya gossypi... 479 e-133
sp|Q6BNP0|ERG27_DEBHA 3-keto-steroid reductase OS=Debaryomyces h... 414 e-114
tr|A3LXN4|A3LXN4_PICST 3-keto-steroid reductase OS=Pichia stipit... 409 e-112
sp|Q874K0|ERG27_CANAL 3-keto-steroid reductase OS=Candida albica... 385 e-105
tr|Q5A888|Q5A888_CANAL Putative uncharacterized protein ERG27 OS... 384 e-105
tr|A5DP65|A5DP65_PICGU Putative uncharacterized protein OS=Pichi... 384 e-105
tr|A5DS22|A5DS22_LODEL 3-keto-steroid reductase OS=Lodderomyces ... 340 7e-92
sp|Q6CE88|ERG27_YARLI 3-keto-steroid reductase OS=Yarrowia lipol... 269 3e-70
tr|O74732|O74732_SCHPO 3-keto sterol reductase (Predicted) OS=Sc... 190 1e-46
tr|Q1L846|Q1L846_SCHPO MRNA, , clone: SY 1224. (Fragment) OS=Sch... 189 2e-46
tr|A1CI81|A1CI81_ASPCL 3-ketosteroid reductase OS=Aspergillus cl... 144 8e-33
tr|A1CWI0|A1CWI0_NEOFI 3-ketosteroid reductase OS=Neosartorya fi... 140 1e-31
tr|Q4WQ42|Q4WQ42_ASPFU 3-ketosteroid reductase OS=Aspergillus fu... 135 3e-30
tr|B0Y6Y0|B0Y6Y0_ASPFC 3-ketosteroid reductase OS=Aspergillus fu... 135 3e-30
tr|A2QIW8|A2QIW8_ASPNG Contig An04c0170, complete genome OS=Aspe... 135 3e-30
tr|B2ARA6|B2ARA6_PODAN Predicted CDS Pa_4_8110 (Fragment) OS=Pod... 134 1e-29
tr|B0DK69|B0DK69_LACBS Predicted protein OS=Laccaria bicolor (st... 132 2e-29
tr|Q7S2G4|Q7S2G4_NEUCR Predicted protein OS=Neurospora crassa GN... 131 6e-29
tr|Q2GSF4|Q2GSF4_CHAGB Putative uncharacterized protein OS=Chaet... 131 7e-29
tr|Q2UJU4|Q2UJU4_ASPOR RIB40 genomic DNA, SC003 OS=Aspergillus o... 129 4e-28
tr|B2VZ18|B2VZ18_PYRTR 3-keto-steroid reductase OS=Pyrenophora t... 128 7e-28
tr|A6RK35|A6RK35_BOTFB Putative uncharacterized protein OS=Botry... 123 2e-26
tr|Q873W7|Q873W7_BOTFU 3-ketosteroid reductase OS=Botryotinia fu... 123 2e-26
tr|A7E4V4|A7E4V4_SCLS1 Putative uncharacterized protein OS=Scler... 121 6e-26
tr|Q5B1J5|Q5B1J5_EMENI Putative uncharacterized protein OS=Emeri... 121 8e-26
tr|Q0UPX0|Q0UPX0_PHANO Putative uncharacterized protein OS=Phaeo... 118 8e-25
tr|Q1E788|Q1E788_COCIM Putative uncharacterized protein OS=Cocci... 117 1e-24
tr|A8PGT7|A8PGT7_COPC7 Putative uncharacterized protein OS=Copri... 116 2e-24
tr|Q0CQV2|Q0CQV2_ASPTN Putative uncharacterized protein OS=Asper... 111 9e-23
tr|Q498H1|Q498H1_XENLA MGC114978 protein OS=Xenopus laevis GN=MG... 110 2e-22
tr|A6QVZ6|A6QVZ6_AJECN Putative uncharacterized protein OS=Ajell... 106 2e-21
tr|B1WBE8|B1WBE8_XENTR Hydroxysteroid (17-beta) dehydrogenase 7 ... 105 4e-21
tr|Q08BC5|Q08BC5_DANRE Zgc:153977 OS=Danio rerio GN=zgc:153977 P... 96 5e-18
tr|Q55TX0|Q55TX0_CRYNE Putative uncharacterized protein OS=Crypt... 95 7e-18
tr|Q5KIG8|Q5KIG8_CRYNE 3-keto sterol reductase, putative OS=Cryp... 94 1e-17
sp|O88736|DHB7_MOUSE 3-keto-steroid reductase OS=Mus musculus GN... 93 3e-17
tr|A4FUD2|A4FUD2_BOVIN HSD17B7 protein OS=Bos taurus GN=HSD17B7 ... 92 5e-17
tr|A9XTK4|A9XTK4_BOVIN 17-beta hydroxysteroid dehydrogenase OS=B... 91 2e-16
tr|Q8C5N9|Q8C5N9_MOUSE 13 days embryo male testis cDNA, RIKEN fu... 90 3e-16
tr|Q4PAG8|Q4PAG8_USTMA Putative uncharacterized protein OS=Ustil... 89 4e-16
tr|Q4H426|Q4H426_9HYPO Putative uncharacterized protein EF101 OS... 88 7e-16
tr|Q5T246|Q5T246_HUMAN Hydroxysteroid (17-beta) dehydrogenase 7 ... 87 1e-15
sp|P56937|DHB7_HUMAN 3-keto-steroid reductase OS=Homo sapiens GN... 87 1e-15
tr|Q2XQY1|Q2XQY1_MACFA 17-beta hydroxysteroid dehydrogenase 7 OS... 87 2e-15
tr|A4RL41|A4RL41_MAGGR Putative uncharacterized protein OS=Magna... 87 2e-15
sp|Q62904|DHB7_RAT 3-keto-steroid reductase OS=Rattus norvegicus... 86 4e-15
tr|Q9BDW7|Q9BDW7_RABIT 17-beta-hydroxysteroid dehydrogenase type... 85 8e-15
tr|A8Q4L3|A8Q4L3_MALGO Putative uncharacterized protein OS=Malas... 84 1e-14
tr|B3RNM2|B3RNM2_9METZ Putative uncharacterized protein OS=Trich... 75 7e-12
tr|Q9N0M8|Q9N0M8_CALJA 17beta-hydroxysteroid dehydrogenase type ... 75 9e-12
tr|A6NH47|A6NH47_HUMAN Uncharacterized protein HSD17B7P2 OS=Homo... 70 3e-10
tr|Q9NRW5|Q9NRW5_HUMAN 17-beta-hydroxysteroid dehydrogenase type... 69 4e-10
tr|Q6IPC1|Q6IPC1_HUMAN HSD17B7P2 protein OS=Homo sapiens GN=HSD1... 63 4e-08
>sp|Q6FIV3|ERG27_CANGA 3-keto-steroid reductase OS=Candida glabrata GN=ERG27 PE=3 SV=1
Length = 348
Score = 718 bits (1854), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MTSKTRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVA 60
MTSKTRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVA
Sbjct: 1 MTSKTRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVA 60
Query: 61 TQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQ 120
TQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQ
Sbjct: 61 TQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQ 120
Query: 121 VLSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWIS 180
VLSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWIS
Sbjct: 121 VLSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWIS 180
Query: 181 SIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYS 240
SIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYS
Sbjct: 181 SIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYS 240
Query: 241 FAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSA 300
FAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSA
Sbjct: 241 FAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSA 300
Query: 301 SSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIPI 348
SSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIPI
Sbjct: 301 SSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIPI 348
>tr|A7A105|A7A105_YEAS7 3-keto sterol reductase OS=Saccharomyces cerevisiae (strain YJM789)
GN=ERG27 PE=4 SV=1
Length = 347
Score = 544 bits (1401), Expect = e-153, Method: Compositional matrix adjust.
Identities = 256/345 (74%), Positives = 301/345 (87%), Gaps = 2/345 (0%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFV--ATQE 63
RKVA++TG NSNLGLNI +RLIE + +VRLT+VVTSRTLPRV+EV+ IK F + +
Sbjct: 3 RKVAIVTGTNSNLGLNIVFRLIETEDTNVRLTIVVTSRTLPRVQEVINQIKDFYNKSGRV 62
Query: 64 DPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLS 123
+ +DFDYLLVDFTNMVSVLNAYYD+N+KY +INY FVNAAQG++DGIDWIGAVK+V +
Sbjct: 63 EDLEIDFDYLLVDFTNMVSVLNAYYDINKKYRAINYLFVNAAQGIFDGIDWIGAVKEVFT 122
Query: 124 DPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIM 183
+PLEAVTNPTY+ QLVGVKSKD+MGL+FQANVFGPYY I KILPQL++GKA +VWISSIM
Sbjct: 123 NPLEAVTNPTYKIQLVGVKSKDDMGLIFQANVFGPYYFISKILPQLTRGKAYIVWISSIM 182
Query: 184 ADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYSFAK 243
+DPK+LSL DIE++K++ +YEGSKR+VDLLHLATYK +K GI+QYVVQPGIFTS+SF+K
Sbjct: 183 SDPKYLSLNDIELLKTNASYEGSKRLVDLLHLATYKDLKKLGINQYVVQPGIFTSHSFSK 242
Query: 244 YLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSR 303
YLNFFT FGML LFYLARLLGS WHNIDGYKAANAPVYV L NP+FE Q+VKYGSA+SR
Sbjct: 243 YLNFFTYFGMLCLFYLARLLGSPWHNIDGYKAANAPVYVTRLANPNFEKQDVKYGSATSR 302
Query: 304 DGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIPI 348
DGM YI+T +ID TG SDV AYI+KKKLEWD KLKDQI +R PI
Sbjct: 303 DGMPYIKTQEIDPTGMSDVFAYIQKKKLEWDKKLKDQIVETRTPI 347
>sp|Q12452|ERG27_YEAST 3-keto-steroid reductase OS=Saccharomyces cerevisiae GN=ERG27 PE=1
SV=1
Length = 347
Score = 543 bits (1399), Expect = e-153, Method: Compositional matrix adjust.
Identities = 255/345 (73%), Positives = 302/345 (87%), Gaps = 2/345 (0%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFV--ATQE 63
RKVA++TG NSNLGLNI +RLIE + +VRLT+VVTSRTLPRV+EV+ IK F + +
Sbjct: 3 RKVAIVTGTNSNLGLNIVFRLIETEDTNVRLTIVVTSRTLPRVQEVINQIKDFYNKSGRV 62
Query: 64 DPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLS 123
+ +DFDYLLVDFTNMVSVLNAYYD+N+KY +INY FVNAAQG++DGIDWIGAVK+V +
Sbjct: 63 EDLEIDFDYLLVDFTNMVSVLNAYYDINKKYRAINYLFVNAAQGIFDGIDWIGAVKEVFT 122
Query: 124 DPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIM 183
+PLEAVTNPTY+ QLVGVKSKD+MGL+FQANVFGPYY I KILPQL++GKA +VWISSIM
Sbjct: 123 NPLEAVTNPTYKIQLVGVKSKDDMGLIFQANVFGPYYFISKILPQLTRGKAYIVWISSIM 182
Query: 184 ADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYSFAK 243
+DPK+LSL DIE++K++ +YEGSKR+VDLLHLATYK +K GI+QYVVQPGIFTS+SF++
Sbjct: 183 SDPKYLSLNDIELLKTNASYEGSKRLVDLLHLATYKDLKKLGINQYVVQPGIFTSHSFSE 242
Query: 244 YLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSR 303
YLNFFT FGML LFYLARLLGS WHNIDGYKAANAPVYV L NP+FE Q+VKYGSA+SR
Sbjct: 243 YLNFFTYFGMLCLFYLARLLGSPWHNIDGYKAANAPVYVTRLANPNFEKQDVKYGSATSR 302
Query: 304 DGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIPI 348
DGM YI+T +ID TG SDV AYI+KKKLEWD+KLKDQI +R PI
Sbjct: 303 DGMPYIKTQEIDPTGMSDVFAYIQKKKLEWDEKLKDQIVETRTPI 347
>tr|B3LT69|B3LT69_YEAST 3-keto sterol reductase OS=Saccharomyces cerevisiae RM11-1a
GN=SCRG_05085 PE=4 SV=1
Length = 347
Score = 543 bits (1399), Expect = e-153, Method: Compositional matrix adjust.
Identities = 255/345 (73%), Positives = 302/345 (87%), Gaps = 2/345 (0%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFV--ATQE 63
RKVA++TG NSNLGLNI +RLIE + +VRLT+VVTSRTLPRV+EV+ IK F + +
Sbjct: 3 RKVAIVTGTNSNLGLNIVFRLIETEDTNVRLTIVVTSRTLPRVQEVINQIKDFYNKSGRV 62
Query: 64 DPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLS 123
+ +DFDYLLVDFTNMVSVLNAYYD+N+KY +INY FVNAAQG++DGIDWIGAVK+V +
Sbjct: 63 EDLEIDFDYLLVDFTNMVSVLNAYYDINKKYRAINYLFVNAAQGIFDGIDWIGAVKEVFT 122
Query: 124 DPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIM 183
+PLEAVTNPTY+ QLVGVKSKD+MGL+FQANVFGPYY I KILPQL++GKA +VWISSIM
Sbjct: 123 NPLEAVTNPTYKIQLVGVKSKDDMGLIFQANVFGPYYFISKILPQLTRGKAYIVWISSIM 182
Query: 184 ADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYSFAK 243
+DPK+LSL DIE++K++ +YEGSKR+VDLLHLATYK +K GI+QYVVQPGIFTS+SF++
Sbjct: 183 SDPKYLSLNDIELLKTNASYEGSKRLVDLLHLATYKDLKKLGINQYVVQPGIFTSHSFSE 242
Query: 244 YLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSR 303
YLNFFT FGML LFYLARLLGS WHNIDGYKAANAPVYV L NP+FE Q+VKYGSA+SR
Sbjct: 243 YLNFFTYFGMLCLFYLARLLGSPWHNIDGYKAANAPVYVTRLANPNFEKQDVKYGSATSR 302
Query: 304 DGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIPI 348
DGM YI+T +ID TG SDV AYI+KKKLEWD+KLKDQI +R PI
Sbjct: 303 DGMPYIKTQEIDPTGMSDVFAYIQKKKLEWDEKLKDQIVETRTPI 347
>sp|Q6CJC2|ERG27_KLULA 3-keto-steroid reductase OS=Kluyveromyces lactis GN=ERG27 PE=3 SV=1
Length = 346
Score = 514 bits (1323), Expect = e-144, Method: Compositional matrix adjust.
Identities = 241/344 (70%), Positives = 288/344 (83%)
Query: 5 TRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQED 64
+ KVAV+TG NSNLGLNI YRLIER + LT+VVTSRTLPRVRE ++LIK FV T
Sbjct: 3 SSKVAVVTGTNSNLGLNIVYRLIERSEPEDNLTIVVTSRTLPRVRECIDLIKAFVNTINR 62
Query: 65 PCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSD 124
SVD+DYLLVDFTNM+S+L+A+Y L+++Y+ INYFFVNAAQGVY GIDW+GAVK+V S
Sbjct: 63 TGSVDYDYLLVDFTNMISILDAHYSLSKRYDHINYFFVNAAQGVYSGIDWLGAVKEVFSS 122
Query: 125 PLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIMA 184
PLEAVTNPTY+ Q VGVKSKD MGLVFQANVFGPYYLIQK+LP L G+ TVVW+SSIM+
Sbjct: 123 PLEAVTNPTYKIQRVGVKSKDGMGLVFQANVFGPYYLIQKLLPLLQAGQGTVVWVSSIMS 182
Query: 185 DPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYSFAKY 244
PK+LSLQDI++++SDV+YEGSKR+VDLLH ATYK+MK GI QY+ PGIFTS SF +Y
Sbjct: 183 APKYLSLQDIQLLESDVSYEGSKRLVDLLHSATYKEMKKLGIRQYLTHPGIFTSLSFFQY 242
Query: 245 LNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSRD 304
LN FT +GMLFLFYLAR +GS WHNI GYKAANAPVYVAT+ NPHFE +++KYGSA+ RD
Sbjct: 243 LNVFTYYGMLFLFYLARWIGSPWHNIQGYKAANAPVYVATMANPHFEKEQMKYGSATFRD 302
Query: 305 GMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIPI 348
G+EYI+T ++D TG DV YI KL+WD+KLKDQI +RIP+
Sbjct: 303 GLEYIKTDEVDTTGCEDVYKYISNLKLQWDEKLKDQIKPTRIPL 346
>tr|A7TJ17|A7TJ17_VANPO Putative uncharacterized protein OS=Vanderwaltozyma polyspora
(strain ATCC 22028 / DSM 70294) GN=Kpol_1033p20 PE=4
SV=1
Length = 345
Score = 510 bits (1314), Expect = e-143, Method: Compositional matrix adjust.
Identities = 243/343 (70%), Positives = 291/343 (84%), Gaps = 1/343 (0%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKVA++TG NSNLGLNI YRL+ER+ D RLT+VVTSRTLPRVREV++ IKK+ P
Sbjct: 4 RKVAIVTGTNSNLGLNIVYRLLEREDPDTRLTIVVTSRTLPRVREVIDQIKKYADKLNRP 63
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
VD+DYLLVDFTNMVSVL+AY DL +KY++I+YFFVNAAQGVYDGIDW+GA KQ L+ P
Sbjct: 64 GVVDYDYLLVDFTNMVSVLSAYNDL-KKYKAIHYFFVNAAQGVYDGIDWVGATKQSLTAP 122
Query: 126 LEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIMAD 185
+EAVTNP YR Q VGVKSKD MGLVFQANVFGPYYLIQKILPQL G A +VW+SS+M+D
Sbjct: 123 MEAVTNPNYRIQRVGVKSKDGMGLVFQANVFGPYYLIQKILPQLVAGHARIVWVSSLMSD 182
Query: 186 PKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYSFAKYL 245
PK+LS D++MIKSDVTYEGSKR+VDLLHLA+YK + S+GI QY+V PGIF S SF K+L
Sbjct: 183 PKYLSFNDLQMIKSDVTYEGSKRLVDLLHLASYKDLASKGIKQYLVHPGIFQSNSFNKFL 242
Query: 246 NFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSRDG 305
N FT +GMLF+FYLARLLGSKWHNI GYKAANAPVYVAT+ + + + Q++KYGSA++ D
Sbjct: 243 NVFTYYGMLFMFYLARLLGSKWHNIVGYKAANAPVYVATMKDTNIKDQQLKYGSATTWDA 302
Query: 306 MEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIPI 348
EYIET +ID TGS+DVL Y++ K EWD+KLK+QITN+R+PI
Sbjct: 303 REYIETQEIDSTGSNDVLKYMDNLKNEWDEKLKNQITNTRVPI 345
>sp|Q74ZZ0|ERG27_ASHGO 3-keto-steroid reductase OS=Ashbya gossypii GN=ERG27 PE=3 SV=1
Length = 348
Score = 479 bits (1233), Expect = e-133, Method: Compositional matrix adjust.
Identities = 227/330 (68%), Positives = 272/330 (82%)
Query: 16 SNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDPCSVDFDYLLV 75
SNLGLNIAYRLIE+ + D +L +VVTSRTLPRVREVV+LIK + +VDFDYLLV
Sbjct: 16 SNLGLNIAYRLIEQFTDDSKLVIVVTSRTLPRVREVVDLIKTYAEKCGKSGAVDFDYLLV 75
Query: 76 DFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPTYR 135
DFT+MVSVL A Y+L ++Y++I+YF+ NAAQGVY GIDW+GA K VL DPL+AVTNPTY+
Sbjct: 76 DFTDMVSVLGAAYELEKRYDAIHYFYANAAQGVYSGIDWLGATKAVLRDPLDAVTNPTYK 135
Query: 136 KQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIMADPKHLSLQDIE 195
Q VGVKS+D +GLVFQANVFGPYYLI++I+P L+KGKA VVW+SS+M+D K+LSL+D+E
Sbjct: 136 IQRVGVKSRDGLGLVFQANVFGPYYLIRRIIPLLAKGKAKVVWLSSLMSDVKYLSLEDVE 195
Query: 196 MIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSYSFAKYLNFFTTFGMLF 255
++++D +YEGSKR+VDLLHLATYK++KS GIHQYV PGIFTS+SF +YLNFFT +GMLF
Sbjct: 196 LLRTDSSYEGSKRLVDLLHLATYKELKSLGIHQYVTHPGIFTSHSFYQYLNFFTYYGMLF 255
Query: 256 LFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSRDGMEYIETTDID 315
LFYLAR LGS WHNI GYK ANAP+YVATL NP FEHQ +KYGSA+ RDGMEYI +ID
Sbjct: 256 LFYLARWLGSPWHNIQGYKGANAPIYVATLANPTFEHQALKYGSATYRDGMEYIAKHEID 315
Query: 316 KTGSSDVLAYIEKKKLEWDDKLKDQITNSR 345
TG D YI EWD KLKDQIT R
Sbjct: 316 PTGMHDAYKYIRDLAEEWDIKLKDQITIGR 345
>sp|Q6BNP0|ERG27_DEBHA 3-keto-steroid reductase OS=Debaryomyces hansenii GN=ERG27 PE=3
SV=1
Length = 346
Score = 414 bits (1064), Expect = e-114, Method: Compositional matrix adjust.
Identities = 204/343 (59%), Positives = 263/343 (76%), Gaps = 7/343 (2%)
Query: 7 KVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDPC 66
KVA+ITG +SNLG+NIAYRL+E+ + +TL+VTSRTLP+V+EV+ I ++ T+ +
Sbjct: 9 KVALITGTSSNLGINIAYRLLEQLPSSTNVTLIVTSRTLPKVKEVITNINQYSKTKLNRT 68
Query: 67 S-VDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
++FDYLLVDFT+MVSVL+AYYDLN+K++ I+Y FVNAAQGVY GIDW+ A K++ +P
Sbjct: 69 GQLEFDYLLVDFTDMVSVLSAYYDLNKKFKKIDYLFVNAAQGVYSGIDWVAATKEICRNP 128
Query: 126 LEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIMAD 185
+E VTNPTY+ Q VGVKS D MGLVFQANVFGPYYLI KI L KG ++WISS+M++
Sbjct: 129 MEGVTNPTYKTQRVGVKSNDNMGLVFQANVFGPYYLIHKIKHLLQKG-GRIIWISSLMSN 187
Query: 186 PKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQ-GIHQYVVQPGIFTSYSFAKY 244
PK+LS D++++KS +YEGSKR+VDL+H T+KQ++S+ GI QY+VQPGIFTS+SF K+
Sbjct: 188 PKYLSFNDLQLLKSPESYEGSKRLVDLMHFGTFKQLQSEYGIEQYLVQPGIFTSFSFFKF 247
Query: 245 LNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSRD 304
LN FT + ML LFYLARL GS HNI G+ AANAPV A L N E Q VK S S+R
Sbjct: 248 LNVFTYYSMLMLFYLARLFGSPSHNISGFIAANAPVTCA-LGN---ESQSVKVCSVSNRT 303
Query: 305 GMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIP 347
G EY+ ++D TGS+D+ AY+EK EWD LKDQI N+R P
Sbjct: 304 GKEYLSYQEVDTTGSADISAYLEKLCHEWDLTLKDQIVNTRQP 346
>tr|A3LXN4|A3LXN4_PICST 3-keto-steroid reductase OS=Pichia stipitis GN=ERG27 PE=4 SV=2
Length = 346
Score = 409 bits (1050), Expect = e-112, Method: Compositional matrix adjust.
Identities = 207/347 (59%), Positives = 257/347 (74%), Gaps = 8/347 (2%)
Query: 4 KTRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQ- 62
K +VAVITG +SNLGLNIAYRL+E+ LTLVVTSRTLP+V++++ IK +V
Sbjct: 5 KEGQVAVITGTSSNLGLNIAYRLVEQTDPKTNLTLVVTSRTLPKVKDIITTIKDYVVEHF 64
Query: 63 -EDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQV 121
E ++FDYLLVDF +MVS+L+AYY+LN++Y I+Y FVNAAQGVY GIDWIGA K++
Sbjct: 65 PERVSKIEFDYLLVDFVDMVSILSAYYELNKRYRHIDYLFVNAAQGVYGGIDWIGATKEI 124
Query: 122 LSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISS 181
L+DP+E VT+PTY+ Q VGVKS D MGLVFQANVFGPYY I +I L G +VWISS
Sbjct: 125 LTDPIEGVTHPTYKIQKVGVKSSDGMGLVFQANVFGPYYFIHRIKHLLQNG-GRIVWISS 183
Query: 182 IMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQM-KSQGIHQYVVQPGIFTSYS 240
IM+ PK+LS D+++IKS +YEGSKR+VDLLH TYK + K I Q +V PGIFTS+S
Sbjct: 184 IMSKPKYLSFNDLQLIKSPESYEGSKRLVDLLHFGTYKTLAKDYNIQQSLVHPGIFTSFS 243
Query: 241 FAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSA 300
F +YLNFFT + ML LFY+AR GS +HNI GY AANAPV A E Q+VK S
Sbjct: 244 FFQYLNFFTYYSMLVLFYIARWSGSPYHNISGYIAANAPVKCAV----GKEKQDVKVESC 299
Query: 301 SSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIP 347
S+R G EYI +ID TGS DV+AY++K EWD KLKDQIT++R+P
Sbjct: 300 STRYGQEYIRYQEIDSTGSEDVVAYLDKLVQEWDVKLKDQITSTRLP 346
>sp|Q874K0|ERG27_CANAL 3-keto-steroid reductase OS=Candida albicans GN=ERG27 PE=3 SV=1
Length = 346
Score = 385 bits (988), Expect = e-105, Method: Compositional matrix adjust.
Identities = 200/348 (57%), Positives = 258/348 (74%), Gaps = 10/348 (2%)
Query: 4 KTRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQE 63
K VAVITG +SNLG NIA RL+E + +TLVVTSRTLP+V+EV+ IKK++ ++
Sbjct: 5 KDSTVAVITGTSSNLGFNIAVRLLEGLPDNKEITLVVTSRTLPKVKEVISDIKKYIV-EK 63
Query: 64 DPCSV---DFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQ 120
P V +FDYLLVDFT+MVS+L+AYY+LN++Y+ I+Y F+NAAQGVY GIDW GAV +
Sbjct: 64 IPTKVNKVEFDYLLVDFTDMVSILSAYYELNKRYKHIDYLFINAAQGVYGGIDWTGAVLE 123
Query: 121 VLSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWIS 180
VL P+EAVTNPTY+ Q VGV+S D++GLVFQANVFGPYY I +I L K +VWIS
Sbjct: 124 VLQSPIEAVTNPTYKLQKVGVESGDKLGLVFQANVFGPYYFIHRI-KHLLKNGGKIVWIS 182
Query: 181 SIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQ-GIHQYVVQPGIFTSY 239
S+M+ PK+LS D+++++S +YEGSKR+VDL+H TY +++ + GI QY+V PGIFTS+
Sbjct: 183 SLMSSPKYLSFNDLQLLRSPASYEGSKRLVDLMHFGTYNKLEREYGIKQYLVHPGIFTSF 242
Query: 240 SFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGS 299
SF +YLN FT +GMLFLFYLAR LGS +HNI GY AANAPV A Q K S
Sbjct: 243 SFFQYLNVFTYYGMLFLFYLARFLGSPYHNISGYIAANAPVAAAL----GQTKQNCKTAS 298
Query: 300 ASSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIP 347
A +R G EY+ +ID TGS DV++Y++ EWD+KLKDQI N+R P
Sbjct: 299 ACTRSGKEYLLEEEIDSTGSDDVVSYLDTLTKEWDEKLKDQIVNTRQP 346
>tr|Q5A888|Q5A888_CANAL Putative uncharacterized protein ERG27 OS=Candida albicans GN=ERG27
PE=4 SV=1
Length = 346
Score = 384 bits (986), Expect = e-105, Method: Compositional matrix adjust.
Identities = 198/347 (57%), Positives = 255/347 (73%), Gaps = 8/347 (2%)
Query: 4 KTRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQ- 62
K VAVITG +SNLG NIA RL+E + +TLVVTSRTLP+V+EV+ IKK++ +
Sbjct: 5 KDSTVAVITGTSSNLGFNIAVRLLEGLPDNKEITLVVTSRTLPKVKEVISDIKKYIVAKI 64
Query: 63 -EDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQV 121
V+FDYLLVDFT+MVS+L+AYY+LN++Y+ I+Y F+NAAQGVY GIDW GAV +V
Sbjct: 65 PTKVNKVEFDYLLVDFTDMVSILSAYYELNKRYKHIDYLFINAAQGVYGGIDWTGAVLEV 124
Query: 122 LSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISS 181
L P+EAVTNPTY+ Q VGV+S D++GLVFQANVFGPYY I +I L G +VW+SS
Sbjct: 125 LQSPIEAVTNPTYKLQKVGVESGDKLGLVFQANVFGPYYFIHRIKHLLENG-GKIVWVSS 183
Query: 182 IMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQM-KSQGIHQYVVQPGIFTSYS 240
+M+ PK+LS D+++++S +YEGSKR+VDL+H TY ++ + GI QY+V PGIFTS+S
Sbjct: 184 LMSSPKYLSFNDLQLLRSPASYEGSKRLVDLMHFGTYNKLEREHGIKQYLVHPGIFTSFS 243
Query: 241 FAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSA 300
F +YLN FT +GMLFLFYLAR LGS +HNI GY AANAPV A Q K SA
Sbjct: 244 FFQYLNVFTYYGMLFLFYLARFLGSPYHNISGYIAANAPVAAAL----GQTKQNCKTASA 299
Query: 301 SSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSRIP 347
+R G EY+ +ID TGS DV++Y++ EWD+KLKDQI N+R P
Sbjct: 300 CTRSGKEYLLEEEIDSTGSDDVVSYLDTLTKEWDEKLKDQIVNTRQP 346
>tr|A5DP65|A5DP65_PICGU Putative uncharacterized protein OS=Pichia guilliermondii
GN=PGUG_05066 PE=4 SV=2
Length = 343
Score = 384 bits (985), Expect = e-105, Method: Compositional matrix adjust.
Identities = 200/347 (57%), Positives = 268/347 (77%), Gaps = 9/347 (2%)
Query: 1 MTSKTRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVA 60
MT+ + KVA+ITG +SNLG+NIAYRL+++ ++LT++VTSRT + +E +ELI ++
Sbjct: 1 MTTNS-KVALITGISSNLGINIAYRLLDQTDPAMKLTIIVTSRTFRKTKESIELINEYAN 59
Query: 61 TQEDP--CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAV 118
++ + +V+FDYLLVDFT+MVSVL+AYYDL+ KY+SI+Y FVNAAQGVY GIDW+GA
Sbjct: 60 SKAESRTGTVEFDYLLVDFTDMVSVLSAYYDLHLKYKSIDYVFVNAAQGVYSGIDWVGAC 119
Query: 119 KQVLSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVW 178
KQ+L +P+E V+ P Y+ Q VGVK+ D MGLVFQANVFGP+YLI KI L KG +VVW
Sbjct: 120 KQILRNPVEGVSFPDYKLQRVGVKTADGMGLVFQANVFGPFYLIHKI-KHLLKG-GSVVW 177
Query: 179 ISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTS 238
ISS+M+ PK+LS D+++++S +YEGSKR+VDL+H+ +Y++++ ++QYVV+PGIFTS
Sbjct: 178 ISSLMSKPKYLSFDDLQLLRSSESYEGSKRLVDLMHMGSYRELEKIHVNQYVVEPGIFTS 237
Query: 239 YSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYG 298
+SF +YLN FT +GML LFYLARLLGS H I GYKAANAPV A P + VK G
Sbjct: 238 FSFFQYLNVFTYYGMLLLFYLARLLGSSHHTISGYKAANAPVSCALSQEP----KNVKLG 293
Query: 299 SASSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSR 345
SA+SR G+EY+ DID TG+ DV AY+ + EWD+KLKDQIT +R
Sbjct: 294 SATSRTGVEYLIRHDIDPTGAEDVAAYLNRLCDEWDEKLKDQITETR 340
>tr|A5DS22|A5DS22_LODEL 3-keto-steroid reductase OS=Lodderomyces elongisporus GN=LELG_00158
PE=4 SV=1
Length = 320
Score = 340 bits (873), Expect = 7e-92, Method: Compositional matrix adjust.
Identities = 175/323 (54%), Positives = 236/323 (73%), Gaps = 8/323 (2%)
Query: 26 LIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQ--EDPCSVDFDYLLVDFTNMVSV 83
++E+ +TL+VTSRTLP+ E+++ IKKF+ + V+FDY+LVDF +MVS+
Sbjct: 1 MLEQLPDKSNITLIVTSRTLPKAIELIKDIKKFIVENVPQKLSYVEFDYILVDFADMVSI 60
Query: 84 LNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPTYRKQLVGVKS 143
L++YY+LN++Y+ I+Y F+NAAQGVY GIDW AV +VL +P++AVT+PTY+ Q GV+S
Sbjct: 61 LSSYYELNKRYKHIDYLFINAAQGVYSGIDWGAAVVEVLKNPMQAVTDPTYKLQRTGVES 120
Query: 144 KDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIMADPKHLSLQDIEMIKSDVTY 203
D++GLVFQANVFGPYY I KI L G +VWI SIM+ PK+LS D+++++S +Y
Sbjct: 121 NDKLGLVFQANVFGPYYFIHKIEHLLENG-GKIVWIGSIMSHPKYLSFNDLQLLRSHESY 179
Query: 204 EGSKRVVDLLHLATYKQMKSQG-IHQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARL 262
EGSKR+VDL+H ATY+++K + I QY+V PGIFTS+SF +YLNFFT +GM+FLFY+AR
Sbjct: 180 EGSKRLVDLMHFATYEKLKREKQIEQYLVHPGIFTSFSFFQYLNFFTYYGMMFLFYMARW 239
Query: 263 LGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSRDGMEYIETTDIDKTGSSDV 322
LGS +HNI GY AANAPV A Q K GSA R G EY+ ++D TG DV
Sbjct: 240 LGSPYHNISGYIAANAPVAAALGKTK----QSAKVGSACDRAGKEYLIYEEVDTTGKDDV 295
Query: 323 LAYIEKKKLEWDDKLKDQITNSR 345
Y+E LEWD+KLK+QI+NSR
Sbjct: 296 GKYLEDLSLEWDEKLKNQISNSR 318
>sp|Q6CE88|ERG27_YARLI 3-keto-steroid reductase OS=Yarrowia lipolytica GN=ERG27 PE=3 SV=1
Length = 343
Score = 269 bits (687), Expect = 3e-70, Method: Compositional matrix adjust.
Identities = 146/339 (43%), Positives = 207/339 (61%), Gaps = 3/339 (0%)
Query: 4 KTRKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQE 63
KT+ V VITGA+SNLG+ I RLI+ + D LT+VVTSRTL VR ++ +K +E
Sbjct: 6 KTQTV-VITGASSNLGIAIGKRLIDEKKEDAHLTIVVTSRTLRNVRVAIKTLKAHAVAKE 64
Query: 64 DPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLS 123
VDFDYLL D +M S+ A +L ++ I+ N+ Y GI+W A+ + +
Sbjct: 65 VGPEVDFDYLLFDLADMTSINGALVELKLRFSRIDTLIFNSNAANYIGINWPLAMWRFTT 124
Query: 124 DPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGKATVVWISSIM 183
+ NP+ Q VGVKS D MG +Q+NVFGP+Y++ ++ QL G V+WISSI
Sbjct: 125 QFKSEIENPSCMIQAVGVKSDDGMGSAYQSNVFGPWYMVLELTEQLKNG-GKVIWISSIT 183
Query: 184 ADPKHLSLQDIEMIKSDVTYEGSKRVVDLLH-LATYKQMKSQGIHQYVVQPGIFTSYSFA 242
+ K++ L+DIE+I + Y+GSKR++D+ H + K + GI+ Y+ PGIFTS S +
Sbjct: 184 SSEKYVDLEDIELIHNKEPYKGSKRLIDVAHNYYSPKLEEEHGIYSYLTDPGIFTSSSAS 243
Query: 243 KYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASS 302
+YLN F+ FGM +FY ARL+G NID YK AN PV+V +P +E + GS +
Sbjct: 244 EYLNIFSAFGMYLMFYFARLIGLTTMNIDPYKGANVPVWVTLSEDPSALKREYRLGSRTG 303
Query: 303 RDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQI 341
R G E ++ T + GS +V AYI+K EW +KLKDQI
Sbjct: 304 RWGTEMMDATKLQYEGSEEVGAYIDKGVGEWREKLKDQI 342
>tr|O74732|O74732_SCHPO 3-keto sterol reductase (Predicted) OS=Schizosaccharomyces pombe
GN=erg27 PE=2 SV=1
Length = 338
Score = 190 bits (482), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 109/341 (31%), Positives = 188/341 (55%), Gaps = 17/341 (4%)
Query: 6 RKVAVITGANSNLGLNIAYRLIE-----RQSADVRLTLVVTSRTLPRVREVVELIKKFVA 60
RK A+ITG+NS LG IA RL++ Q T+++T R+ + + +K+F
Sbjct: 4 RKYALITGSNSGLGFGIATRLLQFYQPRLQDEPEVFTVILTCRSREKAEDACRRLKEFFP 63
Query: 61 TQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQ 120
++ + +Y+L+D +NM SV A D+ ++ +++ ++NA +GI W+ A+
Sbjct: 64 DRK----IRLEYVLLDLSNMASVEAAVQDIATRFPKLDFVYLNAGAWDLEGIQWLKAIFS 119
Query: 121 VLSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILP-QLSKGKATVVWI 179
L +P++A+T+PT+ K+ G S D +G +F++NVFG +YL ++ ++ + VV
Sbjct: 120 TLINPIQALTHPTFYKETAGRVSNDSLGYIFESNVFGHFYLKNRLAELKVLRSSTKVVLT 179
Query: 180 SSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGIFTSY 239
SS++A+ K L +D++ + Y+ SKR++D+LH A + K QY+V PG+ T+
Sbjct: 180 SSLVAEKKSLDFEDLQCFHGEQPYQSSKRLLDVLHYAELE--KGLPFEQYLVHPGLCTTN 237
Query: 240 SFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGS 299
+ +L FY+ RLLGS WH I Y AA A ++ T ++ E Q +K+G+
Sbjct: 238 MYETFLGPILVMCAKLGFYICRLLGSPWHTISPYVAAFA--FLWTALHATKEDQSIKWGA 295
Query: 300 ASSRDGMEYIETTDIDKTGSSD---VLAYIEKKKLEWDDKL 337
A +R G E + +T ++ S+ L Y+ K EW KL
Sbjct: 296 AVTRFGHERVLSTPVELILPSEQEKALEYMTKLYQEWKKKL 336
>tr|Q1L846|Q1L846_SCHPO MRNA, , clone: SY 1224. (Fragment) OS=Schizosaccharomyces pombe
PE=2 SV=1
Length = 342
Score = 189 bits (480), Expect = 2e-46, Method: Compositional matrix adjust.
Identities = 109/346 (31%), Positives = 190/346 (54%), Gaps = 17/346 (4%)
Query: 1 MTSKTRKVAVITGANSNLGLNIAYRLIE-----RQSADVRLTLVVTSRTLPRVREVVELI 55
+T RK A+ITG+NS LG IA RL++ Q T+++T R+ + + +
Sbjct: 3 LTMSFRKYALITGSNSGLGFGIATRLLQFYQPRLQDEPEVFTVILTCRSREKAEDACRRL 62
Query: 56 KKFVATQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWI 115
K+F ++ + +Y+L+D +NM SV A D+ ++ +++ ++N+ +GI W+
Sbjct: 63 KEFFPDRK----IRLEYVLLDLSNMASVEAAVQDIATRFPKLDFVYLNSGSWDLEGIQWL 118
Query: 116 GAVKQVLSDPLEAVTNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILP-QLSKGKA 174
A+ L +P++A+T+PT+ K+ G S D +G +F++NVFG +YL ++ ++ +
Sbjct: 119 KAIFSTLINPIQALTHPTFYKETAGRVSNDSLGYIFESNVFGHFYLKNRLAELKVLRSST 178
Query: 175 TVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPG 234
VV SS++A+ K L +D++ + Y+ SKR++D+LH A + K QY+V PG
Sbjct: 179 KVVLTSSLVAEKKSLDFEDLQCFHGEQPYQSSKRLLDVLHYAELE--KGLPFEQYLVHPG 236
Query: 235 IFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQE 294
+ T+ + +L FY+ RLLGS WH I Y AA A ++ T ++ E Q
Sbjct: 237 LCTTNMYETFLGPILVMCPKLGFYICRLLGSPWHTISPYVAAFA--FLWTALHATKEDQS 294
Query: 295 VKYGSASSRDGMEYIETTDIDKTGSSD---VLAYIEKKKLEWDDKL 337
+K+G+A +R G E + +T ++ S+ L Y+ K EW KL
Sbjct: 295 IKWGAAVTRFGHERVLSTPVELILPSEQEKALEYMTKLYQEWKKKL 340
>tr|A1CI81|A1CI81_ASPCL 3-ketosteroid reductase OS=Aspergillus clavatus GN=ACLA_050580 PE=4
SV=1
Length = 452
Score = 144 bits (363), Expect = 8e-33, Method: Compositional matrix adjust.
Identities = 103/374 (27%), Positives = 171/374 (45%), Gaps = 61/374 (16%)
Query: 10 VITGANSNLGLNIAYRLIE-----RQSADVRLTLVVTSRTLPRVREVVELIKKFVATQED 64
++TGANS LG +I RL++ Q+++ LT++ T+R+ + + + ++ + T
Sbjct: 17 LVTGANSGLGFSICCRLVDDFLKAHQNSNQSLTIIFTTRSTKKGNDTLLRLQDHLRTSSP 76
Query: 65 PCS-------VDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGA 117
S V F VD +N+VSV LNQ ++ +NA G + GI W A
Sbjct: 77 SSSNATAAARVTFIPENVDLSNLVSVRALSRRLNQTLPKLDAIVLNAGLGGWTGIHWPKA 136
Query: 118 VKQVLSDPLEAVTNPTYRKQLVGV---------KSKDEMGLVFQANVFGPYYLIQKILPQ 168
+ VL+D + V+ P+++ G+ ++ +G VF ANVFG Y L ++P
Sbjct: 137 IWGVLTDLVHEVSWPSFKLAPAGMVTDPQTSLGAAEPRLGAVFCANVFGHYMLAHNVMPL 196
Query: 169 LSK-----GKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHL-----ATY 218
L + G V+W+SS+ A + D++ +++ YE SK + D+L L +T
Sbjct: 197 LQRSGRPNGPGRVIWVSSLEASANLFDIDDLQGLRTLAPYESSKALTDILALTSNLPSTA 256
Query: 219 KQMKS------------------QGIHQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLA 260
++S Q + Y+ PGI + F + ML F+LA
Sbjct: 257 PWVRSFYSTDDIDNDSNDKTQHLQPPNTYLTHPGICGTGILPLSWPLF--YAMLCAFWLA 314
Query: 261 RLLGSKWHNIDGYKAANAPVYVATLINPHFEHQE----------VKYGSASSRDGMEYIE 310
RLLGS WH + Y A APV++A + E K+GS+ S G +
Sbjct: 315 RLLGSPWHTVSTYMGACAPVWLALAAQSDLDAAEAPYLRNAGGRAKWGSSCSWSGRDAPA 374
Query: 311 TTDIDKTGSSDVLA 324
+T++D G V+
Sbjct: 375 STEVDGWGYGGVVG 388
>tr|A1CWI0|A1CWI0_NEOFI 3-ketosteroid reductase OS=Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181) GN=NFIA_104700 PE=4 SV=1
Length = 450
Score = 140 bits (353), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 103/376 (27%), Positives = 170/376 (45%), Gaps = 63/376 (16%)
Query: 10 VITGANSNLGLNIAYRLIER-----QSADVRLTLVVTSRTLPRVREVVELIKKFV----- 59
++TGANS LG +I RL++ + LT++ T+R+ + + + ++ +
Sbjct: 17 LVTGANSGLGFSICCRLVDEFLKSHRHPRESLTVIFTTRSTKKGNDTLLRLQDHLRRTSA 76
Query: 60 ---ATQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIG 116
A V F VD +N+VSV LNQ ++ +NA G + GI+W
Sbjct: 77 SVSAPAAASARVTFVPENVDLSNLVSVRALSRRLNQTLPKLDAIVLNAGLGGWTGINWPK 136
Query: 117 AVKQVLSDPLEAVTNPTYR----------KQLVGVKSKDEMGLVFQANVFGPYYLIQKIL 166
A+ V++D + V+ P+++ + +G + +G VF ANVFG Y L ++
Sbjct: 137 AIWGVMTDLVHEVSWPSFKIAPAGMVTDPQTALGDDKEPRLGAVFCANVFGHYMLAHNVM 196
Query: 167 PQLSK-----GKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLAT---- 217
P L G ++W+SS+ A KHL + DI+ +++ YE SK + D+L L
Sbjct: 197 PLLRHSDTLHGSGRIIWVSSLEATVKHLDIDDIQGLRTLAPYESSKALTDILALTADLPS 256
Query: 218 -----------------YKQMKSQGIH--QYVVQPGIFTSYSFAKYLNFFTTFGMLFLFY 258
+K+ + + H ++ PGI + F + ML F+
Sbjct: 257 TAPWVKSFYSVGEQPEPHKETEQEPAHPNMFLTHPGICGTGILPLSWPLF--YSMLAAFW 314
Query: 259 LARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQE----------VKYGSASSRDGMEY 308
LARLLGS WH I Y A APV++A + E VK+GS+ +R G +
Sbjct: 315 LARLLGSPWHTISTYAGACAPVWLALSAQAVLDDAEAPYRRNGGGRVKWGSSCNRLGQDQ 374
Query: 309 IETTDIDKTGSSDVLA 324
T++D G V+
Sbjct: 375 PVCTEVDGWGYGGVVG 390
>tr|Q4WQ42|Q4WQ42_ASPFU 3-ketosteroid reductase OS=Aspergillus fumigatus GN=AFUA_4G11500
PE=4 SV=1
Length = 450
Score = 135 bits (341), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 63/376 (16%)
Query: 10 VITGANSNLGLNIAYRLIER-----QSADVRLTLVVTSR-------TLPRVRE-VVELIK 56
++TGANS LG +I RL++ + LT++ T+R TL R+++ +
Sbjct: 17 LVTGANSGLGFSICCRLVDEFLKSHRHPRESLTVIFTTRSTRKGNDTLLRLQDHLRRASA 76
Query: 57 KFVATQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIG 116
A V F VD +N+VSV LN+ + ++ +NA G + GI+W
Sbjct: 77 SASAPAAASARVTFVAENVDLSNLVSVRALSRRLNKTFPKLDAIVLNAGLGGWTGINWPK 136
Query: 117 AVKQVLSDPLEAVTNPTYR----------KQLVGVKSKDEMGLVFQANVFGPYYLIQKIL 166
A+ V++D + V+ P+++ + +G + +G VF ANVFG Y L +
Sbjct: 137 AIWGVMTDLVHEVSWPSFKIAPAGMVTDAQTALGDDKEPRLGAVFCANVFGHYMLAHNAM 196
Query: 167 PQLSK-----GKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLAT---- 217
P L G ++W+SS+ A KHL + DI+ +++ YE SK + D+L L
Sbjct: 197 PLLRHSDMLHGPGRIIWVSSLEATVKHLDIDDIQGLRTLAPYESSKALTDILALTADLPS 256
Query: 218 -----------------YKQMKSQGIH--QYVVQPGIFTSYSFAKYLNFFTTFGMLFLFY 258
K+ + + H ++ PGI + F + ML F+
Sbjct: 257 TAPWVKSFYSVDEQPEPRKETELEPPHPNMFLTHPGICGTGILPLSWPLF--YSMLAAFW 314
Query: 259 LARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQE----------VKYGSASSRDGMEY 308
LARLLGS WH I Y A APV++A + E VK+GS+ +R G +
Sbjct: 315 LARLLGSPWHTISTYAGACAPVWLALSAQAVLDDAEAPYRRNGGGRVKWGSSCNRLGQDQ 374
Query: 309 IETTDIDKTGSSDVLA 324
T++D G V+
Sbjct: 375 PVCTEVDGWGYGGVVG 390
>tr|B0Y6Y0|B0Y6Y0_ASPFC 3-ketosteroid reductase OS=Aspergillus fumigatus (strain CEA10 /
CBS 144.89 / FGSC A1163) GN=AFUB_068520 PE=4 SV=1
Length = 450
Score = 135 bits (341), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 63/376 (16%)
Query: 10 VITGANSNLGLNIAYRLIER-----QSADVRLTLVVTSR-------TLPRVRE-VVELIK 56
++TGANS LG +I RL++ + LT++ T+R TL R+++ +
Sbjct: 17 LVTGANSGLGFSICCRLVDEFLKSHRHPRESLTVIFTTRSTRKGNDTLLRLQDHLRRASA 76
Query: 57 KFVATQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIG 116
A V F VD +N+VSV LN+ + ++ +NA G + GI+W
Sbjct: 77 SASAPAAASARVTFVAENVDLSNLVSVRALSRRLNKTFPKLDAIVLNAGLGGWTGINWPK 136
Query: 117 AVKQVLSDPLEAVTNPTYR----------KQLVGVKSKDEMGLVFQANVFGPYYLIQKIL 166
A+ V++D + V+ P+++ + +G + +G VF ANVFG Y L +
Sbjct: 137 AIWGVMTDLVHEVSWPSFKIAPAGMVTDAQTALGDDKEPRLGAVFCANVFGHYMLAHNAM 196
Query: 167 PQLSK-----GKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLAT---- 217
P L G ++W+SS+ A KHL + DI+ +++ YE SK + D+L L
Sbjct: 197 PLLRHSDMLHGPGRIIWVSSLEATVKHLDIDDIQGLRTLAPYESSKALTDILALTADLPS 256
Query: 218 -----------------YKQMKSQGIH--QYVVQPGIFTSYSFAKYLNFFTTFGMLFLFY 258
K+ + + H ++ PGI + F + ML F+
Sbjct: 257 TAPWVKSFYSVDEQPEPRKETELEPPHPNMFLTHPGICGTGILPLSWPLF--YSMLAAFW 314
Query: 259 LARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQE----------VKYGSASSRDGMEY 308
LARLLGS WH I Y A APV++A + E VK+GS+ +R G +
Sbjct: 315 LARLLGSPWHTISTYAGACAPVWLALSAQAVLDDAEAPYRRNGGGRVKWGSSCNRLGQDQ 374
Query: 309 IETTDIDKTGSSDVLA 324
T++D G V+
Sbjct: 375 PVCTEVDGWGYGGVVG 390
>tr|A2QIW8|A2QIW8_ASPNG Contig An04c0170, complete genome OS=Aspergillus niger
GN=An04g05000 PE=4 SV=1
Length = 420
Score = 135 bits (341), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 99/348 (28%), Positives = 159/348 (45%), Gaps = 35/348 (10%)
Query: 10 VITGANSNLGLNIAYRLIE----RQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
++TGANS LGL I RLI + LT++ T+R+ + + ++ + P
Sbjct: 16 LVTGANSGLGLAICARLITDFLTTHPSTHHLTIIFTTRSPKKASSTLHHLQTLLPPISSP 75
Query: 66 CS---VDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVL 122
+ VD +++ SV L ++ +NA G + GIDW A+ L
Sbjct: 76 TQSSRITLHPETVDLSSLPSVRALSQRLTTTIPKLDSIVLNAGIGGWTGIDWPRAIWGTL 135
Query: 123 SDPLEAVTNPTYRKQLVGV--------KSKDEMGLVFQANVFGPYYLIQKILPQLSKG-- 172
+D + +V+ ++ VG+ S+ +G VF ANVFG Y L ++ L K
Sbjct: 136 TDLVHSVSWFAHKIAPVGMITPPQTTQPSEPRLGSVFTANVFGHYMLSHNVMGLLRKSTQ 195
Query: 173 KATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI------ 226
V+W+SSI A H ++ DI+ +++ V YE SK + D+L L K +G
Sbjct: 196 PGRVIWVSSIEATVNHFNVDDIQGLRTKVPYESSKTLTDILALTADNGEKGEGDGEGTRP 255
Query: 227 HQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLI 286
Y+ PG+ + L F + M+ FY+ARLLGS WH + Y A AP ++A
Sbjct: 256 RMYLSHPGVCGTGILPLALPLF--WAMIASFYIARLLGSPWHTLSTYAGACAPTWLAVSR 313
Query: 287 NPHFEHQE----------VKYGSASSRDGMEYIETTDIDKTGSSDVLA 324
+ E VK+GS+ R G + +T++D G V+
Sbjct: 314 QDELDAAEEVYRAHGGGKVKWGSSCDRLGRDKAVSTEVDGWGHGGVVG 361
>tr|B2ARA6|B2ARA6_PODAN Predicted CDS Pa_4_8110 (Fragment) OS=Podospora anserina PE=4 SV=1
Length = 454
Score = 134 bits (336), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 110/391 (28%), Positives = 172/391 (43%), Gaps = 72/391 (18%)
Query: 10 VITGANSNLGLNIAYRLIE----RQSADVRLTLVVTSRTLPRVREVVELIK----KFVAT 61
++TGANS +G I RLI+ +S L L+ T+R+ + +E V ++ +F +
Sbjct: 21 LVTGANSGIGFGICQRLIDDYLSTRSLTSHLILIPTTRSAKKSQETVTALRAHALQFAES 80
Query: 62 QE----------DPCS----VDFDYLLVDFTNMVSVLNAYYDL----------------- 90
DP + + +D N+ S+ A L
Sbjct: 81 SPALRSRTGQNYDPHQATRRIHILSVQLDLCNLPSITAAADQLLHGTLSSSPSTSPDFES 140
Query: 91 --NQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPL-EAVTNPTYRKQLVG------V 141
+ K ++ NA G + G++W +L+ + A T PT++ G
Sbjct: 141 LEDVKIPRLDSIIFNAGIGGWYGLNWGKVAHNILTKGIVSATTWPTFKGGNSGQTIAPVP 200
Query: 142 KSKDEMGLVFQANVFGPYYLIQKILPQLSKGKAT------VVWISSIMADPKHLSLQDIE 195
SK+ MG VF ANVFG Y QK++P LS+ K + ++W SSI AD SL+D +
Sbjct: 201 GSKETMGEVFCANVFGHYLFAQKLVPLLSRPKPSALPPGRIIWESSIDADWDTFSLEDFQ 260
Query: 196 MIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQ-------------YVVQPGIFTSYSFA 242
+K+D YE +KR+ D+L L + + Q Y+ PGI + F
Sbjct: 261 ALKTDAAYESTKRLTDVLALTSSLPTSKPYVDQYFSVAEDETPPKMYLAHPGIVQTTLFP 320
Query: 243 KYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEH---QEVKYGS 299
LN F F + YL R LGS WH I GY + AP ++A + + VK+GS
Sbjct: 321 --LNAFMFFWYQVVLYLVRWLGSPWHPITGYNGSMAPAWLALQEQEALDSERAERVKWGS 378
Query: 300 ASSRDGMEYIETTDIDKTGSSDVLAYIEKKK 330
A+ R G Y+ T++D G + +E+ K
Sbjct: 379 AADRWGNVYVRKTEVDGWGWEGRVEDVEELK 409
>tr|B0DK69|B0DK69_LACBS Predicted protein OS=Laccaria bicolor (strain S238N-H82)
GN=LACBIDRAFT_303734 PE=4 SV=1
Length = 419
Score = 132 bits (333), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 104/380 (27%), Positives = 175/380 (46%), Gaps = 68/380 (17%)
Query: 1 MTSKTRKVAVITGANSNLGLNIAYRLI------------------ERQSADVR-----LT 37
M ++ + V+TGAN+ +G I RL+ + Q+ ++ LT
Sbjct: 1 MVISSKPIIVVTGANAGVGFGICQRLLFQLSQAYPTDALPQAFAPDTQTTEIPTTYDGLT 60
Query: 38 LVVTSRTLPRVREV-VELIKKFVATQE----DPC----------SVDFDYLLVDFTNMVS 82
L++ R+ R E +L++ F A E P +VD + +D ++VS
Sbjct: 61 LIMACRSEKRAAEARAKLLRLFNAHVEILRKSPNYDGHAHKFRENVDIQFHYLDLASIVS 120
Query: 83 VLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPTYRKQLVGVK 142
V +L+Q+Y I++ NA + G+ W +Q +DP+ VT+P + Q G
Sbjct: 121 VFRFAEELSQRYPYISHLICNAGVNSFKGLHWPTFFQQFFTDPVGVVTHPRFNLQHKGEL 180
Query: 143 SKDEMGLVFQANVFGPYYLIQKILPQL--SKGKATVVWISSIMADPKHLSLQDIEMIKSD 200
S D +G V+Q N F Y L +++ P L S +A V+W SS+ A P +D ++ +D
Sbjct: 181 SIDGLGWVWQCNTFSHYTLFRELQPLLTASPTEARVIWSSSLEALPCFYDSEDWQLKNTD 240
Query: 201 VTYEGSKRVVDLLHLATYKQM------KSQGIHQYVVQPGIFTSYSFAKYLNFFTTFGML 254
+YEGSK +DL+ A +Q S+ I ++ QPG+ + + F +
Sbjct: 241 HSYEGSKYQIDLIATALEQQSIQEVAPDSKRIRHFISQPGVCNTQVVP--VGMVLDFIKV 298
Query: 255 FLFYLARLLGSKWHNIDGYKAANAPVYVA----TLINPHFEHQE---------------- 294
LFYLARL GS HNI+ +K+A A V++ I P +
Sbjct: 299 ILFYLARLFGSVNHNIEPFKSAIATVHLVLAPLCFITPLMGSRSLAPANETNSDLLGTHP 358
Query: 295 VKYGSASSRDGMEYIETTDI 314
+++GS + R G E++ T++
Sbjct: 359 IRFGSQTERWGDEHVGLTEV 378
>tr|Q7S2G4|Q7S2G4_NEUCR Predicted protein OS=Neurospora crassa GN=NCU05991 PE=4 SV=1
Length = 475
Score = 131 bits (330), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 110/390 (28%), Positives = 174/390 (44%), Gaps = 82/390 (21%)
Query: 9 AVITGANSNLGLNIAYRLIER----QSADVRLTLVVTSRTLPRVREVVELIKK----FVA 60
A++TGANS +G I RLI+ +S L ++ T+R++ + +E ++ +++ F
Sbjct: 17 ALVTGANSGIGFAICQRLIDEYLVTRSLTSHLVVIPTTRSVKKSQETIDALRQHAREFAT 76
Query: 61 TQE----------DPCSV----DFDYLLVDFTNMVSV-----------LNAYYDLNQKY- 94
T + DP S+ + +D N+ V +++ D N Y
Sbjct: 77 TSDILRSRAGPNYDPRSITKRIHILSVQLDLCNLADVHRAAEQLVNGTVSSPADANDVYF 136
Query: 95 --------ESINYFFVNAAQGVYDGIDWIGAVKQVLSDPL-EAVTNPTYRKQLVG----- 140
++ NA G + G+DW + + L +A T PT++ G
Sbjct: 137 TSLTDVRIPRLDAVIFNAGMGGWTGLDWPKVFHNIFTKGLVQATTWPTFKAATAGHVVNP 196
Query: 141 -VKSKDE----MGLVFQANVFGPYYLIQKILPQLSKGK-------ATVVWISSIMADPKH 188
+KDE MG VF ANVFG Y L K++P LS+ + ++W SSI K+
Sbjct: 197 LPDAKDEKVPEMGQVFCANVFGHYLLAHKLVPLLSRSEFDSTIPPGRIIWESSIEPGWKN 256
Query: 189 LSLQDIEMIKSDVTYEGSKRVVDLLHL-----------------ATYKQMKSQGIHQYVV 231
LSL D + IK++ YE +KR+ D+L L AT + Y+V
Sbjct: 257 LSLSDFQAIKTNAAYESTKRLTDVLSLTATLPSARPFVDSYLQPATKSNAPATPPRIYLV 316
Query: 232 QPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHF- 290
PGI + F LN F F + Y+AR LGS WH I GY A APV++A
Sbjct: 317 HPGIVQTTLFP--LNAFMFFWYRVVLYIARWLGSPWHPITGYNGAVAPVWLALQEQEALD 374
Query: 291 --EHQEVKYGSASSRDGMEYIETTDIDKTG 318
+ + VK+GS++ G + T+++ G
Sbjct: 375 AVDAEHVKWGSSTDFWGECRVLKTEVEGWG 404
>tr|Q2GSF4|Q2GSF4_CHAGB Putative uncharacterized protein OS=Chaetomium globosum
GN=CHGG_09100 PE=4 SV=1
Length = 466
Score = 131 bits (330), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 104/386 (26%), Positives = 168/386 (43%), Gaps = 79/386 (20%)
Query: 10 VITGANSNLGLNIAYRLIER----QSADVRLTLVVTSRTLPRVREVVELIKK----FVAT 61
++TG NS +G I RLI+ +S L ++ T+R++ + +E ++ ++K F T
Sbjct: 18 LVTGGNSGIGFGIGERLIDEYLTTRSLSSHLVVIPTTRSIKKSQETIDGLRKHAREFAET 77
Query: 62 QE----------DPCS----VDFDYLLVDFTNMVSVLNAYYDL----------------- 90
DP V + +D N+ SV L
Sbjct: 78 STALRARAGPNYDPKQTTRRVHILSVQLDLCNLPSVRRCANQLVSGTVSSPSDDNDFVSI 137
Query: 91 -NQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPL-EAVTNPTYRKQLVG-------- 140
+ K ++ NA G + G++W +L+ L A T PT++ L G
Sbjct: 138 SDAKIPRLDSIIFNAGMGGWYGLNWPKVFHNILTKGLVNATTWPTFKGGLSGHKIDPIKG 197
Query: 141 ---VKSKDEMGLVFQANVFGPYYLIQKILPQLSKG------KATVVWISSIMADPKHLSL 191
K ++MG VF ANVFG Y Q+++P L++ ++W SS+ D + LS
Sbjct: 198 TKGEKGTEQMGEVFCANVFGHYVFAQRLVPLLTRATDSTLPPGRIIWESSVEGDWESLSQ 257
Query: 192 QDIEMIKSDVTYEGSKRVVDLLHL----------------ATYKQMKSQGIHQYVVQPGI 235
D E +K++ YE +KR+ DL+ L T K++ Y+V PG+
Sbjct: 258 DDFEAVKTEAAYESTKRLTDLMALTATLPTSQPSVAKYLNTTSTTPKTRPPKIYLVHPGV 317
Query: 236 FTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEH--- 292
+ F LN F F + Y+AR LGS WH I Y A APV+VA +
Sbjct: 318 VQTTLFP--LNAFMFFWYNIVLYVARWLGSPWHPITAYNGACAPVWVALQEQGWLDGARA 375
Query: 293 QEVKYGSASSRDGMEYIETTDIDKTG 318
+ VK+G+++ R G ++ T++D G
Sbjct: 376 ERVKWGTSTDRAGECRVKKTEVDGWG 401
>tr|Q2UJU4|Q2UJU4_ASPOR RIB40 genomic DNA, SC003 OS=Aspergillus oryzae GN=AO090003001070
PE=4 SV=1
Length = 455
Score = 129 bits (323), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 103/388 (26%), Positives = 171/388 (44%), Gaps = 67/388 (17%)
Query: 10 VITGANSNLGLNIAYRLIER-----QSADVRLTLVVTSRTLPRVREVVELI----KKFVA 60
++TGANS LG +I RL++ Q + LT++ T+R+ + + ++ + +K A
Sbjct: 17 LVTGANSGLGFSICCRLVDEFLNSPQRTNQSLTVIFTTRSPKKGNDTLQRLQDHLRKTSA 76
Query: 61 TQEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQ 120
T V F VD N+VSV LN +Y ++ +NA G + ++W A+
Sbjct: 77 THSPTRRVTFVPESVDLNNLVSVRALSRRLNDEYPKLDAIMLNAGIGGWSTLNWPRAIWG 136
Query: 121 VLSDPLEAVTNPTYRKQLVGV----------KSKDEMGLVFQANVFGPYYLIQKILPQLS 170
VL+D + V+ P+Y+ G+ + +G VF ANVFG Y L ++P L
Sbjct: 137 VLTDLVHEVSWPSYKIAPAGMVTDYQTTTLAAQEPRLGSVFCANVFGHYMLAHNVMPLLR 196
Query: 171 K-----GKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLA--------- 216
+ G V+W+SS+ A K + DI+ +++ YE SK + D+L L
Sbjct: 197 RSGQPNGPGRVIWVSSLEATVKMFDVDDIQGLRTTAPYESSKALTDVLALTADLPSTKPF 256
Query: 217 -----------TYKQMKSQ---------GIHQYVVQPGIFTSYSFAKYLNFFTTFGMLFL 256
TY + + Y+ PGI + F + ML +
Sbjct: 257 VKSFYSVDDNRTYNSGFGRPRITNDDNLAPNMYLSHPGICGTGIIPLSWPLF--YSMLAI 314
Query: 257 FYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQE----------VKYGSASSRDGM 306
ARLLGS WH + Y A APV++A + E K+GS+++ G
Sbjct: 315 CLFARLLGSPWHTVSTYLGACAPVWLALSAQSVLDTAESLYRQNGGGRAKWGSSTNWVGK 374
Query: 307 EYIETTDIDKTGSSDVL--AYIEKKKLE 332
+ +T+ D G V+ A +++ +L
Sbjct: 375 DTPASTETDGWGYGGVVGPAIVDEDRLR 402
>tr|B2VZ18|B2VZ18_PYRTR 3-keto-steroid reductase OS=Pyrenophora tritici-repentis (strain
Pt-1C-BFP) GN=PTRG_02658 PE=4 SV=1
Length = 440
Score = 128 bits (321), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 107/376 (28%), Positives = 171/376 (45%), Gaps = 58/376 (15%)
Query: 10 VITGANSNLGLNIAYRLIER----QSADVRLTLVVTSRTLPR----VREVVELIKKFVAT 61
++TGANS LGL I RLI+ + L L++T+R + + ++ + + K V
Sbjct: 17 LVTGANSGLGLGIGTRLIDEFLQTRPQSESLVLIITTRDQRKGDATIAKLEQHLCKVVRG 76
Query: 62 QEDPCS---------VDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGI 112
E+ V F +D ++VSV L + ++ NA G + GI
Sbjct: 77 HEEKLPGIAQVLQNRVYFRQERLDLLSLVSVQKLSKKLRETTPKLDVVICNAGIGGWTGI 136
Query: 113 DWIGAVKQVLSDPLEAVTNPTYRKQLVG------------VKSKDEMGLVFQANVFGPYY 160
+W AV +L+ A+T PT++ G V+ + +G VF ANVFG Y
Sbjct: 137 NWPSAVWTILTTWNRALTWPTFKISGKGWVTKPQIPEDKKVEDEPPLGEVFCANVFGHYL 196
Query: 161 LIQKILPQLSKGKAT------VVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLH 214
L + P L++ A+ ++W+SS+ A L D++ I SD+ YE +KR+ D+L
Sbjct: 197 LGHYLAPLLARHAASEKTRGRLIWVSSLEAYDHVFDLDDMQGILSDMPYEVTKRITDVLA 256
Query: 215 LATYKQMKSQGIHQY----------------VVQPGIFTSYSFAKYLNFFTTFGMLFLFY 258
+ + S +++Y V PGI + A L + ML FY
Sbjct: 257 ITSTLPSTSPEVNRYLDHSEDSAKTTKPRLYVTHPGICGTSIMA--LPVILEYCMLIAFY 314
Query: 259 LARLLGSKWHNIDGYKAANAPVYVA-----TLINPHFEHQEVKYGSASSRDGMEYIETTD 313
+AR LGS+WH + K A A V++A TL N + K+GSA+ G E ++ T+
Sbjct: 315 IARFLGSQWHTVTPEKGATAMVWLALADQTTLDNMEAKEGVGKWGSATDAWGRERVDRTE 374
Query: 314 IDKTGSSDVLAYIEKK 329
I G L ++K
Sbjct: 375 IAGWGWGGKLGEYKRK 390
>tr|A6RK35|A6RK35_BOTFB Putative uncharacterized protein OS=Botryotinia fuckeliana (strain
B05.10) GN=BC1G_00806 PE=4 SV=1
Length = 517
Score = 123 bits (308), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 87/293 (29%), Positives = 134/293 (45%), Gaps = 77/293 (26%)
Query: 97 INYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPTYRKQLVGVKSKDEM--------- 147
++ +NA G + GIDW A+ V++D EAVT PTY+ +GV +K ++
Sbjct: 172 LDVVVLNAGIGGWSGIDWPKAIWTVITDMTEAVTWPTYKLAEIGVITKPQLSSASSKQAK 231
Query: 148 ---------------------GLVFQANVFGPYYLIQKILPQLSKGKAT-------VVWI 179
G F +NVFG Y L +++P LS+ + ++W+
Sbjct: 232 PSDDEAAQPLLDGESPEEPPLGATFCSNVFGHYVLAHELMPLLSRTASPSATTSGRIIWV 291
Query: 180 SSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQG-------------- 225
SSI A +H D++ ++S YE SKR+ D+L L+ +++++ G
Sbjct: 292 SSIEAQAQHFDEDDLQGLESRTPYESSKRLTDVLVLS--RKLRAAGQASSSWFDCSDVRV 349
Query: 226 ---------------IHQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNI 270
YVVQPGIF S LNF F +FYL R +GS+WH I
Sbjct: 350 ENSKSEEEPAAKLIRPKMYVVQPGIFVSEIMP--LNFVLVFIYRLIFYLVRWMGSQWHTI 407
Query: 271 DGYKAANAPVYVATLINP-----HFEHQEVKYGSASSRDGMEYIETTDIDKTG 318
Y AA APV+VA ++P + + K+GSA+ G E + T++ G
Sbjct: 408 KPYTAAVAPVWVA--LSPDDVLDNMDGAASKWGSATDASGKERVIRTEVPGWG 458
>tr|Q873W7|Q873W7_BOTFU 3-ketosteroid reductase OS=Botryotinia fuckeliana GN=Erg27 PE=4
SV=1
Length = 535
Score = 123 bits (308), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 87/293 (29%), Positives = 134/293 (45%), Gaps = 77/293 (26%)
Query: 97 INYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPTYRKQLVGVKSKDEM--------- 147
++ +NA G + GIDW A+ V++D EAVT PTY+ +GV +K ++
Sbjct: 190 LDVVVLNAGIGGWSGIDWPKAIWTVITDMTEAVTWPTYKLAEIGVITKPQLSSASSKQAK 249
Query: 148 ---------------------GLVFQANVFGPYYLIQKILPQLSKGKAT-------VVWI 179
G F +NVFG Y L +++P LS+ + ++W+
Sbjct: 250 PSDDEAAQPLLDGESPEEPPLGATFCSNVFGHYVLAHELMPLLSRTASPSATTSGRIIWV 309
Query: 180 SSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQG-------------- 225
SSI A +H D++ ++S YE SKR+ D+L L+ +++++ G
Sbjct: 310 SSIEAQAQHFDEDDLQGLESRTPYESSKRLTDVLVLS--RKLRAAGQASSSWFDCSDVRV 367
Query: 226 ---------------IHQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNI 270
YVVQPGIF S LNF F +FYL R +GS+WH I
Sbjct: 368 ENSKSEEEPAAKLIRPKMYVVQPGIFVSEIMP--LNFVLVFIYRLIFYLVRWMGSQWHTI 425
Query: 271 DGYKAANAPVYVATLINP-----HFEHQEVKYGSASSRDGMEYIETTDIDKTG 318
Y AA APV+VA ++P + + K+GSA+ G E + T++ G
Sbjct: 426 KPYTAAVAPVWVA--LSPDDVLDNMDGAASKWGSATDASGKERVIRTEVPGWG 476
>tr|A7E4V4|A7E4V4_SCLS1 Putative uncharacterized protein OS=Sclerotinia sclerotiorum
(strain ATCC 18683 / 1980 / Ss-1) GN=SS1G_00326 PE=4
SV=1
Length = 541
Score = 121 bits (304), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 85/297 (28%), Positives = 136/297 (45%), Gaps = 79/297 (26%)
Query: 97 INYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPTYRKQLVGVKSKDEM--------- 147
++ +NA G + GI+W A+ V++D EAVT PTY+ VG +K ++
Sbjct: 190 LDVVILNAGIGGWSGINWPKAIWTVMTDMTEAVTWPTYKLAEVGAVTKPQLSSTKPKEAK 249
Query: 148 ---------------------GLVFQANVFGPYYLIQKILPQLSKGKAT-------VVWI 179
G F +NVFG Y L +++P LS+ + ++W+
Sbjct: 250 TSDDESTQPLLNGDSPQEPPLGSTFCSNVFGHYILAHELMPLLSRSASPSATTSGRIIWV 309
Query: 180 SSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI------------- 226
SSI A P+H ++ D++ + + YE SKR+ D+L L+ +++++ G
Sbjct: 310 SSIEAQPQHFNIDDLQGLNNHAPYESSKRLTDVLVLS--RKLRAAGKISSSWFDCSDVRV 367
Query: 227 --HQ--------------------YVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLG 264
H+ YVVQPGIF S LNF F +FYL R +G
Sbjct: 368 KEHEIEEGENAEDRSPTQLIRPKMYVVQPGIFVSEIMP--LNFILVFFYRMIFYLVRWMG 425
Query: 265 SKWHNIDGYKAANAPVYVATLINPHFEHQEV---KYGSASSRDGMEYIETTDIDKTG 318
S+WH I+ Y AA APV++A + + + K+GSA+ G E + T++ G
Sbjct: 426 SQWHTIEPYTAAVAPVWLALSQDEILDTMDAPASKWGSATDSSGKERVIRTEVPGWG 482
>tr|Q5B1J5|Q5B1J5_EMENI Putative uncharacterized protein OS=Emericella nidulans GN=AN5585.2
PE=4 SV=1
Length = 412
Score = 121 bits (303), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 83/298 (27%), Positives = 134/298 (44%), Gaps = 52/298 (17%)
Query: 75 VDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPTY 134
VD N++SV LN+ + ++ +NA G + G++W AV V +D + A T P Y
Sbjct: 55 VDLCNLLSVRALSRRLNKTFPKLDAIVLNAGIGGWSGLNWPLAVWSVCTDIIHATTWPKY 114
Query: 135 RKQLVGVKSKDE----------MGLVFQANVFGPYYLIQKILPQLSK-----GKATVVWI 179
+ VG+ + ++ +G VF ANVFG Y L ++P L + G V+W+
Sbjct: 115 KIAPVGLITDNQTITVTDKEPRLGTVFCANVFGHYMLAHNVMPLLHRSGSPNGPGRVIWL 174
Query: 180 SSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHL------------------------ 215
SS A + D + ++S YE SK + DLL L
Sbjct: 175 SSTEATINFFDVDDFQALRSKAPYESSKALTDLLSLTSDLPSTAPWVKSFYSTDFETDSK 234
Query: 216 -ATYKQMKSQGIHQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYK 274
+T + S + Y+ PGI + L + M+ F+LAR+LGS WH + Y
Sbjct: 235 PSTGPETASTIPNVYLSHPGICATAIIP--LPTILIYAMVAAFWLARILGSPWHTLSTYL 292
Query: 275 AANAPVYVATLINPHFEHQE----------VKYGSASSRDGMEYIETTDIDKTGSSDV 322
A +PV++A + E VK+GS++SR G+ + ++++D G V
Sbjct: 293 GACSPVWLALSTQSELDAAEAPYRKHGGGRVKWGSSASRLGVASVVSSEVDGWGYGGV 350
>tr|Q0UPX0|Q0UPX0_PHANO Putative uncharacterized protein OS=Phaeosphaeria nodorum
GN=SNOG_06194 PE=4 SV=2
Length = 436
Score = 118 bits (295), Expect = 8e-25, Method: Compositional matrix adjust.
Identities = 96/350 (27%), Positives = 164/350 (46%), Gaps = 51/350 (14%)
Query: 16 SNLGLNIAYRLIER----QSADVRLTLVVTSRTLPRVREVVELIKKF---VATQEDPCSV 68
S LGL I+ RLI+ + L L++T+R + +E +++ V + +
Sbjct: 23 SGLGLGISTRLIDEFLQTRPQSESLVLIITTRDQQKGDATIEKLQRHLRQVCEKHEQTLP 82
Query: 69 DFDYLLV----------DFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAV 118
LL+ D ++VSV + ++ NA G + GI+W A+
Sbjct: 83 GISQLLLHRVYFRQERLDLLSLVSVQKLSKRIRDTTPKLDALICNAGIGGWTGINWPVAI 142
Query: 119 KQVLSDPLEAVTNPTYRKQLVGVKSK---------DEMGLVFQANVFGPYYLIQKILPQL 169
+L+ +A+T PT++ +G +K +E+G VF ANVFG Y L + P L
Sbjct: 143 FSILTTWTKALTYPTFKLAAIGRVTKPQSSTTEKGEELGEVFCANVFGHYLLGHYLAPLL 202
Query: 170 SK------GKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKS 223
++ + ++W+SSI A + DI+ + S+V YE SKR+ D+L +++ S
Sbjct: 203 ARHSKSEDTRGRIIWVSSIEAYDFTFDINDIQGLGSEVPYESSKRLTDVLAISSTLPSTS 262
Query: 224 QGIHQYV---------VQPGIFTSY-----SFAKYLNFFTTFGMLFLFYLARLLGSKWHN 269
++QY+ +P I+ S+ + L + M FYLAR LGS+WH
Sbjct: 263 NHVNQYLEYSDSSEKTTKPRIYVSHPGICGTSIVPLPLVLEYLMFAAFYLARFLGSQWHP 322
Query: 270 IDGYKAANAPVYVA-----TLINPHFEHQEVKYGSASSRDGMEYIETTDI 314
+ K A A V++A TL + + K+GSA++ G E +E T++
Sbjct: 323 VTVEKGATAMVWLALANQSTLDSMEKQEGAGKWGSATNFWGQERVERTEV 372
>tr|Q1E788|Q1E788_COCIM Putative uncharacterized protein OS=Coccidioides immitis
GN=CIMG_01575 PE=4 SV=1
Length = 452
Score = 117 bits (292), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 92/367 (25%), Positives = 160/367 (43%), Gaps = 65/367 (17%)
Query: 10 VITGANSNLGLNIAYRLIER----QSADVRLTLVVTSRTLPRVREVVELIKKFV----AT 61
++TG NS LGL+I RLI+ + LTL+ T+R+ + E + +++ + +
Sbjct: 20 LVTGTNSGLGLSICRRLIDEFLHTRPRTQSLTLIFTTRSTRKSNETLAHLQRHLRLAGVS 79
Query: 62 QEDPCSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQV 121
D + VD +++SV L ++ +NA + G++W A+ V
Sbjct: 80 GRDLERITLKPEHVDLCDLLSVRALSRRLLASTPKLDVVVLNAGIAGFSGLNWFRAIYMV 139
Query: 122 LSDPLEAVTNP---------TYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKG 172
L+D + AVT P T K+ + + +G +F ANVFG Y L ++P L K
Sbjct: 140 LTDLIYAVTWPSSYCISPTGTLVKKQTQLPDEPPLGQLFCANVFGHYMLSHNLVPLLKKS 199
Query: 173 --KATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATY------------ 218
++W SS+ A+ + + DI+ +K+ YE K + D+L L +
Sbjct: 200 DIPGRIIWTSSLEANREVFDVSDIQGLKTSRAYESVKYLTDILALTSPLPSTAPWVNSFL 259
Query: 219 ------------------KQMKSQGIHQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLA 260
+++ S YV PGI + L + + M+ F+ A
Sbjct: 260 SSSDDDNHISNGKSSLQDRKLSSTTPSMYVAHPGICATSILPLILPLY--YAMIAAFWFA 317
Query: 261 RLLGSKWHNIDGYKAANAPVYVATLINPH------------FEHQEVKYGSASSRDGMEY 308
R++GS WH + Y+ A A V++A + PH VK+GS+ R G E
Sbjct: 318 RIVGSPWHVLSSYRGAAASVWLA--LAPHSVIDAAEAAYAALGGGRVKWGSSCDRLGRES 375
Query: 309 IETTDID 315
+ T+++
Sbjct: 376 VVCTEVE 382
>tr|A8PGT7|A8PGT7_COPC7 Putative uncharacterized protein OS=Coprinopsis cinerea (strain
Okayama-7 / 130 / FGSC 9003) GN=CC1G_09970 PE=4 SV=1
Length = 426
Score = 116 bits (291), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 94/387 (24%), Positives = 164/387 (42%), Gaps = 75/387 (19%)
Query: 1 MTSKTRKVAVITGANSNLGLNIAYRLIERQSADVR------------------------- 35
M+ + + ++TGAN +G I RL+ + S +
Sbjct: 1 MSDAHKPIIIVTGANGGVGYGICQRLLVQLSEESPPDSLPQAFSDIPQQDGEPLPKASFY 60
Query: 36 --LTLVVTSRTLPRVREVV-ELIKKF--------------VATQEDPCSVDFDYLLVDFT 78
LTL++ R++ R + EL+ F +E ++ D + +D
Sbjct: 61 PGLTLIMACRSVKRAEKAKDELLAWFDQHVKQRRRQTGYTGRAEEVQRNLVVDVVPLDLA 120
Query: 79 NMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPTYRKQL 138
++ +V + ++Y +++ NA + IDWIGA+KQ+ +DP+ A+T+P Y Q
Sbjct: 121 SVKTVFEFAKTVKERYPYVSHIAANAGLASFKSIDWIGAMKQLFTDPMGAMTSPNYYTQH 180
Query: 139 VGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGK--ATVVWISSIMADPKHLSLQDIEM 196
G S D +G V+Q N+FG Y L +++ L+ ++W SS+ A+P H D ++
Sbjct: 181 AGELSVDGLGWVWQCNLFGHYTLFRELESHLAASPLGGRMIWCSSLEANPTHYDSSDWQL 240
Query: 197 IKSDVTYEGSKRVVDLL------------------HLATYKQMKSQG---IHQYVVQPGI 235
+D +Y K +DL+ + + G + ++ P +
Sbjct: 241 RSTDHSYSSVKYQIDLVATTLDRIALSSSSSTSSSSTSQPSSITPSGKLPVRHFISHPAV 300
Query: 236 FTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAP--------VYVATLIN 287
+ A + T F L +FY+ R LGS H I YKAA A VY+A L
Sbjct: 301 SHTNVSAALVGPITNFLKLLVFYIVRFLGSPHHPIQPYKAAIATTHLALVPLVYLAYLSQ 360
Query: 288 PHFEHQEVKYGSASSRDGMEYIETTDI 314
P V+YG+ + R G E + + +
Sbjct: 361 P--TAPPVRYGAETDRWGNERVGISPV 385
>tr|Q0CQV2|Q0CQV2_ASPTN Putative uncharacterized protein OS=Aspergillus terreus (strain NIH
2624) GN=ATEG_03932 PE=4 SV=1
Length = 413
Score = 111 bits (277), Expect = 9e-23, Method: Compositional matrix adjust.
Identities = 83/298 (27%), Positives = 128/298 (42%), Gaps = 50/298 (16%)
Query: 75 VDFTNMVSVLNAYYDLNQKYES---INYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTN 131
VD TN++SV L + ++ +NA G + GIDW A+ V +D + V+
Sbjct: 62 VDLTNLLSVRALARRLTSPSTAPHKLDAVILNAGLGGWTGIDWPRAIWGVCTDLVHQVSW 121
Query: 132 PTYRKQLVGV------KSKDE--MGLVFQANVFGPYYLIQKILPQLSKGKAT----VVWI 179
P+Y+ GV + DE +G VF ANVFG Y L ++P L + A +VW+
Sbjct: 122 PSYKVAPAGVVTAPQTAAPDEPRLGAVFCANVFGHYMLAHYLMPLLHRAPAASPGRIVWV 181
Query: 180 SSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI------------- 226
SS+ A D++ +++ YE SK + D+L L + +
Sbjct: 182 SSLEATASLFDPDDLQGLRTLTPYESSKALTDILALTADLPSAAPWVRSFYALEGKETDE 241
Query: 227 ----------HQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAA 276
+ Y+ PGI + F + ML F+LARLLGS WH + Y A
Sbjct: 242 APPAADAPQPNMYLSHPGICGTGILPLSWPLF--YAMLSSFWLARLLGSPWHTLSTYLGA 299
Query: 277 NAPVYVATLINPHFEHQE----------VKYGSASSRDGMEYIETTDIDKTGSSDVLA 324
APV++A + E K+GS+ R G +T++D G V+
Sbjct: 300 CAPVWLALATQSALDAAEAGYRERGGGRAKWGSSCDRLGRNSAASTEVDGWGYGGVVG 357
>tr|Q498H1|Q498H1_XENLA MGC114978 protein OS=Xenopus laevis GN=MGC114978 PE=2 SV=1
Length = 329
Score = 110 bits (274), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 98/357 (27%), Positives = 165/357 (46%), Gaps = 52/357 (14%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV V+TGANS +GL + RL+ S D ++ L + R L R + P
Sbjct: 2 RKVVVVTGANSGIGLALCERLL---SNDDQIRLCLACRNLQRAEAA-----RSALLSSHP 53
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
S D LLVD + SV+ A +L ++Y+ ++Y ++NA ++ +P
Sbjct: 54 -SADVGVLLVDVGKVKSVVQAAKELKERYKKVDYLYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGV-------------KSKDEMGLVFQANVFGPYYLIQKILPQL 169
L A N + + ++ + ++D + VF+ NVFG + LI++I P L
Sbjct: 98 QISLRAFINGLFSRNVINMFATAEGILTQKDRVTEDGLQEVFETNVFGHFMLIREIEPLL 157
Query: 170 SKGKAT--VVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIH 227
+G +T ++W SS A SL D + +S Y SK DLL +A K QG++
Sbjct: 158 CQGDSTSQLIWTSSSNARKSAFSLSDYQHSQSQEPYSSSKYATDLLSVALNKHYNKQGLY 217
Query: 228 QYVVQPG-IFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLI 286
VV PG + T+ ++ +F T ++ + +L R+ + + I Y A A ++ L
Sbjct: 218 SSVVCPGLVMTNLTYGIMPSFLWTL-IMPIMWLIRIFTNSF-TISTYNGAEALMW---LF 272
Query: 287 NPHFEHQE--VKYGSASSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQI 341
E + KY S +S G Y+ T +D S L + +K LE + +++ +
Sbjct: 273 KQKVESLDPLSKYHSCTSGLGNNYVNLTKMDVEEESGDLLF--QKMLELEKEIRKKC 327
>tr|A6QVZ6|A6QVZ6_AJECN Putative uncharacterized protein OS=Ajellomyces capsulata (strain
NAm1 / WU24) GN=HCAG_01553 PE=4 SV=1
Length = 449
Score = 106 bits (265), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 85/312 (27%), Positives = 132/312 (42%), Gaps = 58/312 (18%)
Query: 75 VDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAVTNPT- 133
VD N++SV L ++ +NA + G+++ A+ L+D + AVT P+
Sbjct: 61 VDLANLLSVRALSRRLRASLPKLDAVILNAGTAGFTGVNFFKALYLTLTDLVNAVTYPSA 120
Query: 134 YRKQLVGVKSKDE--------MGLVFQANVFGPYYLIQKILPQLSKGKAT---VVWISSI 182
+ GV K + +G +F +NVFG Y L ++P LS + + ++WISSI
Sbjct: 121 FTLTCSGVLVKKQTSQPDEPPLGDIFCSNVFGHYMLNHALMPLLSASETSPGRIIWISSI 180
Query: 183 MADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHL----------------------ATYKQ 220
A KH L D + + + Y+ SK + D+L L AT Q
Sbjct: 181 EATSKHFDLSDFQALNTRSAYQASKHLTDVLALTSEHPSSSPWVDTFLSASKTTTATKLQ 240
Query: 221 MKSQGIHQ----------YVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNI 270
H YV PG+ + F + M+ +F+LAR+ GS WH I
Sbjct: 241 QNGTAHHAPTSSRPKPSIYVAHPGVCGTAIMPLVFPLF--YAMIAVFWLARMFGSPWHTI 298
Query: 271 DGYKAANAPVYVATLINPHFEHQE----------VKYGSASSRDGMEYIETTDIDKTGSS 320
Y A APV++A P + E K+GS+ R G T++D G
Sbjct: 299 STYSGAYAPVWLALSPKPVLDAAEDVYARLGGGKPKWGSSCDRLGRISAVCTEVDGWGYG 358
Query: 321 DVL--AYIEKKK 330
V+ A +E+ K
Sbjct: 359 GVVGPAVLEEDK 370
>tr|B1WBE8|B1WBE8_XENTR Hydroxysteroid (17-beta) dehydrogenase 7 OS=Xenopus tropicalis
GN=hsd17b7 PE=2 SV=1
Length = 334
Score = 105 bits (263), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 101/352 (28%), Positives = 166/352 (47%), Gaps = 34/352 (9%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV V+TGANS +GL + RL+ S D ++ L + R L R + P
Sbjct: 2 RKVVVVTGANSGIGLALCERLL---SYDDQIRLCLGCRNLQRAEAA-----RTALLSSHP 53
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
+ D LLVD + SV+ A +L ++Y+ ++Y ++NA + + +K + S
Sbjct: 54 -TADVSVLLVDVGKVTSVVRAAKELKERYKKVDYLYLNAGIMPNPQLSFRAFIKGLFS-- 110
Query: 126 LEAVTNPTYRKQLVGVK----SKDEMGLVFQANVFGPYYLIQKILPQLSKGKAT--VVWI 179
V N + + + ++D + VF+ NVFG + LI++I P L +T ++W
Sbjct: 111 -RNVINMFATAEGILTQKDRITEDGLQEVFETNVFGHFMLIREIEPLLCHADSTSQLIWT 169
Query: 180 SSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPG-IFTS 238
SS A SL D + + Y SK DLL +A KQ QG++ VV PG + T+
Sbjct: 170 SSSNARKSAFSLSDYQHSQGQEPYSSSKYATDLLSVALNKQYNKQGLYSSVVCPGLVMTN 229
Query: 239 YSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQE--VK 296
++ +FF T ++ + +L R+ + + I + A A ++ L N E + K
Sbjct: 230 LTYGIMPSFFWTL-IMPIMWLIRVFTNSF-TISPFNGAEALMW---LFNQKAESLDPLSK 284
Query: 297 YGSASSRDGMEYIETTDID-KTGSSDVLAYIEKKKLEWDDKLKDQITNSRIP 347
Y S +S G Y+ + +D S D+L +K LE L+ +I IP
Sbjct: 285 YHSCTSGLGNNYVCLSKMDVDEKSGDLLL---QKMLE----LEKEICKKSIP 329
>tr|Q08BC5|Q08BC5_DANRE Zgc:153977 OS=Danio rerio GN=zgc:153977 PE=2 SV=1
Length = 340
Score = 95.5 bits (236), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 89/342 (26%), Positives = 159/342 (46%), Gaps = 22/342 (6%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
+KV ++TGANS +GL + RL+ + D ++ L + R + R E +K +
Sbjct: 2 KKVVLVTGANSGIGLALCERLL---NEDAQIELCLACRNMQRA----EAARKALLVSHPQ 54
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
V +L D NM SV+ + +K+ ++Y ++NA +D + + + S
Sbjct: 55 ARVSLLHL--DVGNMHSVVKGAEEFKKKFNRLDYLYLNAGIMPNPTVDHVAFYRGLFSR- 111
Query: 126 LEAVTNPTYRKQLVGVKSK-DEMGL--VFQANVFGPYYLIQKILPQLSKGK--ATVVWIS 180
A+ T + ++ + K +GL VF N+FG + L++++ P L + + + V+W S
Sbjct: 112 -NAIKMLTTGEGILTQEDKVTPIGLQEVFATNLFGHFLLVKELEPLLCQTEHNSLVIWTS 170
Query: 181 SIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPG-IFTSY 239
S A +L+D++ + Y SK DLL LA + SQG+ V+ PG + T+
Sbjct: 171 SSNAQRSSFNLEDVQHKNGPLPYSSSKYASDLLSLALNRHYNSQGMFSSVICPGLVMTNL 230
Query: 240 SFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGS 299
++ + F T M LF L R+ + + + Y A A +Y P KY S
Sbjct: 231 TYGILPSLFWTIIMPILF-LIRIFTNSF-TLSPYNGAEA-LYWLFKQKPESLDPMAKYHS 287
Query: 300 ASSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQI 341
+S G Y + +D + Y+ K LE +D ++ ++
Sbjct: 288 LTSGLGNNYTRPSKMDLDENMSEAFYV--KLLELEDTVRKKL 327
>tr|Q55TX0|Q55TX0_CRYNE Putative uncharacterized protein OS=Cryptococcus neoformans
GN=CNBD3330 PE=4 SV=1
Length = 438
Score = 95.1 bits (235), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 96/402 (23%), Positives = 169/402 (42%), Gaps = 84/402 (20%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQS---------------------------------- 31
R +A++TGANS GL I ++L+ S
Sbjct: 15 RVIALVTGANSGYGLGICHQLLSNLSLPSTVPIPASTPQPTALAPSMRDSIPSNSLRPTK 74
Query: 32 ---ADVRLTLVVTSRTLPRVREVVELI------------KKFVATQE---DPCSVDFDYL 73
D LTL++ R+ + +E ++++ KK +A ++ + + ++ +
Sbjct: 75 TSVPDTTLTLILACRSGAKAQEAIDMLWKKHKSDLEKRKKKGLAVKKGWLEGLRIVWEGV 134
Query: 74 LVDFTNMVSVLNAYYD-LNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLE-AVTN 131
+D + + A+ + + +Y I F+NA G + GID+ KQ+ +D + A++
Sbjct: 135 NLDSPGGTNGILAFTERVKNRYPHITCLFLNAGMGAFSGIDYCKFTKQIFTDGMSVALSQ 194
Query: 132 PTYRKQLVGVKSKD-EMGLVFQANVFGPYYLIQKILPQLSKGKAT------VVWISSIMA 184
P + ++ G KS D E GLV+ NV PY + +++LP L + VV+ SS A
Sbjct: 195 PQFNIEIKGAKSADGERGLVWGTNVLAPYIMARELLPMLRRSPPELPFAPRVVYTSSGTA 254
Query: 185 DPKHLS---LQDIEMIKSDVTYEGSKRVVDLLHL--------ATYKQMKSQGIHQYVVQP 233
L+ L D ++ D +Y SK + D++ L T K+ +G+ ++P
Sbjct: 255 TLSKLNNHPLDDYMLLDYDESYGASKYMGDMVMLQLDREFNDETTKRDDDRGVRVLTIEP 314
Query: 234 GIFTSYSFAKYLNF------FTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLIN 287
G + F L F F FY+ RLLGS +H + + A P+ A LI
Sbjct: 315 GCVATNFFNAGLGAWAWWIKFKWFWYWLSFYICRLLGSPYHPVYADQGA-LPMLYAALIP 373
Query: 288 PHF-----EHQEVKYGSASSRDGMEYIETTDIDKTGSSDVLA 324
F + K+ + R G + +ID+ +D L
Sbjct: 374 AAFLLSPSQVPAQKFEVRAQRWGNTKVGYGEIDRWEEADALG 415
>tr|Q5KIG8|Q5KIG8_CRYNE 3-keto sterol reductase, putative OS=Cryptococcus neoformans
GN=CND03020 PE=4 SV=1
Length = 629
Score = 94.0 bits (232), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 96/402 (23%), Positives = 169/402 (42%), Gaps = 84/402 (20%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQS---------------------------------- 31
R +A++TGANS GL I ++L+ S
Sbjct: 15 RVIALVTGANSGYGLGICHQLLSNLSLPSTVPIPASTPQPTALAPSMRDSIPSNSLRPTK 74
Query: 32 ---ADVRLTLVVTSRTLPRVREVVELI------------KKFVATQE---DPCSVDFDYL 73
D LTL++ R+ + +E ++++ KK +A ++ + + ++ +
Sbjct: 75 TSVPDTTLTLILACRSGAKAQEAIDMLWKKHKSDLEKRKKKGLAVKKGWLEGLRIVWEGV 134
Query: 74 LVDFTNMVSVLNAYYD-LNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLE-AVTN 131
+D + + A+ + + +Y I F+NA G + GID+ KQ+ +D + A++
Sbjct: 135 NLDSPGGTNGILAFTERVKNRYPHITCLFLNAGMGAFSGIDYCKFTKQIFTDGMSVALSQ 194
Query: 132 PTYRKQLVGVKSKD-EMGLVFQANVFGPYYLIQKILPQLSKGKAT------VVWISSIMA 184
P + ++ G KS D E GLV+ NV PY + +++LP L + VV+ SS A
Sbjct: 195 PQFNIEIKGAKSADGERGLVWGTNVLAPYIMARELLPMLRRSPPELPFAPRVVYTSSGTA 254
Query: 185 DPKHLS---LQDIEMIKSDVTYEGSKRVVDLLHL--------ATYKQMKSQGIHQYVVQP 233
L+ L D ++ D +Y SK + D++ L T K+ +G+ ++P
Sbjct: 255 TLSKLNNHPLDDYMLLDYDESYGASKYMGDMVMLQLDREFNDETTKRDDDRGVRVLTIEP 314
Query: 234 GIFTSYSFAKYLNF------FTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLIN 287
G + F L F F FY+ RLLGS +H + + A P+ A LI
Sbjct: 315 GCVATNFFNAGLGAWAWWIKFKWFWYWLSFYICRLLGSPYHPVYADQGA-LPMLYAALIP 373
Query: 288 PHF-----EHQEVKYGSASSRDGMEYIETTDIDKTGSSDVLA 324
F + K+ + R G + +ID+ +D L
Sbjct: 374 AAFLLSPSQVPAQKFEVRAQRWGNTKVGYGEIDRWEEADALG 415
>sp|O88736|DHB7_MOUSE 3-keto-steroid reductase OS=Mus musculus GN=Hsd17b7 PE=2 SV=1
Length = 334
Score = 92.8 bits (229), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 89/348 (25%), Positives = 166/348 (47%), Gaps = 51/348 (14%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R L + R V + + +A+
Sbjct: 2 RKVVLITGASSGIGLALCGRLL---AEDDDLHLCLACRNLSKARAVRDTL---LASHP-- 53
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
S + + +D +++ SV+ ++ QK++ ++Y ++NA +L +P
Sbjct: 54 -SAEVSIVQMDVSSLQSVVRGAEEVKQKFQRLDYLYLNAG---------------ILPNP 97
Query: 126 ---LEAVTNPTYRKQLV-------GVKSK------DEMGLVFQANVFGPYYLIQKILPQL 169
L+A + + ++ G+ ++ D + VF+ N+FG + LI+++ P L
Sbjct: 98 QFNLKAFFCGIFSRNVIHMFTTAEGILTQNDSVTADGLQEVFETNLFGHFILIRELEPLL 157
Query: 170 SKG--KATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIH 227
+ ++W SS A + SL+DI+ K Y SK DLL++A + +G++
Sbjct: 158 CHADNPSQLIWTSSRNAKKANFSLEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLY 217
Query: 228 QYVVQPG-IFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLI 286
V+ PG + T+ ++ F T +L + +L R + + Y A A V++
Sbjct: 218 SSVMCPGVVMTNMTYGILPPFIWTL-LLPIMWLLRFFVNAL-TVTPYNGAEALVWLFHQ- 274
Query: 287 NPHFEHQEVKYGSASSRDGMEYI--ETTDIDKTGSS---DVLAYIEKK 329
P + KY SA+S G Y+ + DID+ + +VL +EK+
Sbjct: 275 KPESLNPLTKYASATSGFGTNYVTGQKMDIDEDTAEKFYEVLLELEKR 322
>tr|A4FUD2|A4FUD2_BOVIN HSD17B7 protein OS=Bos taurus GN=HSD17B7 PE=2 SV=1
Length = 334
Score = 92.0 bits (227), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 88/359 (24%), Positives = 165/359 (45%), Gaps = 46/359 (12%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+E A L L + R + + V +A+
Sbjct: 2 RKVVLITGASSGVGLALCRRLLEEDDA---LHLCLACRNMSKAEAVR---TSLLASHP-- 53
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
+ + + VD +++ SV A +L Q+++ ++Y ++NA ++ +P
Sbjct: 54 -AAEVSIVQVDVSSLPSVFQATKELKQRFQRLDYVYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKSKDEMGL--------------VFQANVFGPYYLIQKILPQ 168
++A+ + ++++ + S E GL VF+ NVFG + LIQ++
Sbjct: 98 QLNIKALFRGLFSRKVIHMFSTAE-GLLTQNDKITPDGLQEVFETNVFGHFILIQELESL 156
Query: 169 L--SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI 226
L S+ + ++W SS A + S +D++ K Y SK +DLL +A + QG+
Sbjct: 157 LCHSESPSQLIWTSSRNAKKSNFSFEDVQHSKGQEPYSSSKYAIDLLSVALNRHFNHQGL 216
Query: 227 HQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLI 286
+ VV PG + L F ++ + +L R + + + + A V++
Sbjct: 217 YSSVVCPGTMLTNLTYGILPPFVWMLIMPIIWLLRFFANAF-TLTPHNGTEALVWLFHQ- 274
Query: 287 NPHFEHQEVKYGSASSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSR 345
P + VKY SA++ G Y+ + +D + Y + KLE + ++ Q TN++
Sbjct: 275 KPESLNPLVKYLSATTGFGSNYVTSKKMDLDEDTAEKFYQKLLKLEKEIRVTIQKTNNQ 333
>tr|A9XTK4|A9XTK4_BOVIN 17-beta hydroxysteroid dehydrogenase OS=Bos taurus GN=HSD17B7 PE=2
SV=1
Length = 334
Score = 90.5 bits (223), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 87/359 (24%), Positives = 164/359 (45%), Gaps = 46/359 (12%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITG +S +GL + RL+E A L L + R + + V +A+
Sbjct: 2 RKVVLITGVSSGVGLALCRRLLEEDDA---LHLCLACRNMSKAEAVR---TSLLASHP-- 53
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
+ + + VD +++ SV A +L Q+++ ++Y ++NA ++ +P
Sbjct: 54 -AAEVSIVQVDVSSLPSVFQATKELKQRFQRLDYVYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKSKDEMGL--------------VFQANVFGPYYLIQKILPQ 168
++A+ + ++++ + S E GL VF+ NVFG + LIQ++
Sbjct: 98 QLNIKALFRGLFSRKVIHMFSTAE-GLLTQNDKITPDGLQEVFETNVFGHFILIQELESL 156
Query: 169 L--SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI 226
L S+ + ++W SS A + S +D++ K Y SK +DLL +A + QG+
Sbjct: 157 LCHSESPSQLIWTSSRNAKKSNFSFEDVQHSKGQEPYSSSKYAIDLLSVALNRHFNHQGL 216
Query: 227 HQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLI 286
+ VV PG + L F ++ + +L R + + + + A V++
Sbjct: 217 YSSVVCPGTMLTNLTYGILPPFVWMLIMPIIWLLRFFANAF-TLTPHNGTEALVWLFHQ- 274
Query: 287 NPHFEHQEVKYGSASSRDGMEYIETTDIDKTGSSDVLAYIEKKKLEWDDKLKDQITNSR 345
P + VKY SA++ G Y+ + +D + Y + KLE + ++ Q TN++
Sbjct: 275 KPESLNPLVKYLSATTGFGSNYVTSKKMDLDEDAAEKFYQKLLKLEKEIRVTIQKTNNQ 333
>tr|Q8C5N9|Q8C5N9_MOUSE 13 days embryo male testis cDNA, RIKEN full-length enriched
library, clone:6030439M15 product:hydroxysteroid 17-beta
dehydrogenase 7, full insert sequence OS=Mus musculus
GN=Hsd17b7 PE=2 SV=1
Length = 362
Score = 89.7 bits (221), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 82/323 (25%), Positives = 153/323 (47%), Gaps = 46/323 (14%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R L + R V + + +A+
Sbjct: 2 RKVVLITGASSGIGLALCGRLL---AEDDDLHLCLACRNLSKARAVRDTL---LASHP-- 53
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
S + + +D +++ SV+ ++ QK++ ++Y ++NA +L +P
Sbjct: 54 -SAEVSIVQMDVSSLQSVVRGAEEVKQKFQRLDYLYLNAG---------------ILPNP 97
Query: 126 ---LEAVTNPTYRKQLV-------GVKSK------DEMGLVFQANVFGPYYLIQKILPQL 169
L+A + + ++ G+ ++ D + VF+ N+FG + LI+++ P L
Sbjct: 98 QFNLKAFFCGIFSRNVIHMFTTAEGILTQNDSVTADGLQEVFETNLFGHFILIRELEPLL 157
Query: 170 SKG--KATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIH 227
+ ++W SS A + SL+DI+ K Y SK DLL++A + +G++
Sbjct: 158 CHADNPSQLIWTSSRNAKKANFSLEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLY 217
Query: 228 QYVVQPG-IFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLI 286
V+ PG + T+ ++ F T +L + +L R + + Y A A V++
Sbjct: 218 SSVMCPGVVMTNMTYGILPPFIWTL-LLPIMWLLRFFVNAL-TVTPYNGAEALVWLFHQ- 274
Query: 287 NPHFEHQEVKYGSASSRDGMEYI 309
P + KY SA+S G Y+
Sbjct: 275 KPESLNPLTKYASATSGFGTNYV 297
>tr|Q4PAG8|Q4PAG8_USTMA Putative uncharacterized protein OS=Ustilago maydis GN=UM02895.1
PE=4 SV=1
Length = 667
Score = 89.0 bits (219), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 70/309 (22%), Positives = 129/309 (41%), Gaps = 66/309 (21%)
Query: 70 FDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAV 129
+++ +D +M S L + ++Y + + +NA + G++W AV +++ AV
Sbjct: 226 IEFVPLDLGSMGSALECARMVRERYSHVTHVVLNAGSSAWTGMNWFHAVWMIMTQFRYAV 285
Query: 130 TNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKG----KATVVWISSIMAD 185
T P Y+ Q G KS D+ G V+Q NV + L++ +LP L + ++W SS+ A
Sbjct: 286 TWPAYKMQRAGDKSDDDFGWVWQCNVGAHWILVRALLPSLRATPYSVPSRIIWTSSVEAF 345
Query: 186 PKHLSLQD---IEMIKSDVTYEGSKRVVDLLHLA-----TYKQMKSQ------------- 224
K+ D +++ KS + YE K +L ++M++Q
Sbjct: 346 SKYYEASDYQCLDVAKSPLPYESVKYQCELAAFGLDDALQTRRMRTQPGTPMEERSTMLG 405
Query: 225 -------GIHQ-------------------------------YVVQPGIFTSYSFAKYLN 246
+H+ ++ PG+ S ++++
Sbjct: 406 MSSTGSESMHRSASSASGTAPHGFLGLPPASRPVPGQPEPRSFLAHPGVVASTMMSQFVA 465
Query: 247 FFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQEVKYGSASSRDGM 306
+ T ++ FY+AR +GS H ID +K A + Y +P + +YGS S G
Sbjct: 466 SWVTIFVVASFYIARWVGSPHHPIDPFKGAISVSYACLAPDP---DPKKRYGSRSDFWGR 522
Query: 307 EYIETTDID 315
EY+ I+
Sbjct: 523 EYVGIEKIE 531
>tr|Q4H426|Q4H426_9HYPO Putative uncharacterized protein EF101 OS=Epichloe festucae
GN=EF101 PE=4 SV=1
Length = 482
Score = 88.2 bits (217), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 87/389 (22%), Positives = 155/389 (39%), Gaps = 84/389 (21%)
Query: 10 VITGANSNLGLNIAYRLIE----RQSADVRLTLVVTSRTLPRVREVVELIKKFVAT---- 61
++TGA S +GL+ LI+ +S + L + T+R+ + +++++
Sbjct: 32 LVTGAGSGIGLSTVQHLIDDFLSSRSLNSHLIAIPTTRSSRNSLATIRVLREYAIKAAQS 91
Query: 62 --------------QEDPCSVDFDYLLVDFTNMVSV-----------------LNAYYDL 90
Q+ + L+VD ++ ++ L+ Y
Sbjct: 92 SAALASRAGPDYKWQDAVARIHILSLIVDLCDLRAIKKLAYTLRYGTVSNPEGLDGEYLR 151
Query: 91 NQKYESINYFFVNAAQGVYDGIDWIGAVKQVL-SDPLEAVTNPTYRKQLV---------- 139
N + ++ NAA G + G+ + A++ +L ++ T P ++ L
Sbjct: 152 NVRIPRLDSIVCNAAYGGWSGMSYPQAIRSLLFKGIIQTATWPEFKLALPTRILNERPSY 211
Query: 140 GVKSKDEMGLVFQANVFGPYYLIQKILPQLSK-----GKATVVWISSIMADPKHLSLQDI 194
+K +G VF A VFG Y L +LP LS+ ++W SS+ A K + DI
Sbjct: 212 NYPAKPLLGEVFSACVFGHYMLGHYLLPLLSRPSTNEAPGRIIWSSSVEAVRKVFDVNDI 271
Query: 195 EMIKSDVTYEGSKRVVDLLHL----------------------ATYKQMKSQGIHQYVVQ 232
+ YE +KR+ DLL L A KQ+ + Y+
Sbjct: 272 QCFTRPEAYESAKRLTDLLSLTYALPAARPYSSRFLTIDDDDEAAAKQVVKPKL--YLTH 329
Query: 233 PGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEH 292
PG+ S F L +F + + R LGS WHN+DGY+ A A V+V +
Sbjct: 330 PGVVASTLFP--LPWFLFWAYKLALIICRWLGSPWHNVDGYRGAKAAVWVVLQDQEALDD 387
Query: 293 ---QEVKYGSASSRDGMEYIETTDIDKTG 318
+K+GS++ ++ T+++ G
Sbjct: 388 VGGDRIKWGSSTDASLQVDVKKTEVEDWG 416
>tr|Q5T246|Q5T246_HUMAN Hydroxysteroid (17-beta) dehydrogenase 7 (HCG2024989, isoform
CRA_a) (cDNA FLJ76137, highly similar to Homo sapiens
hydroxysteroid (17-beta) dehydrogenase 7 (HSD17B7),
mRNA) OS=Homo sapiens GN=HSD17B7 PE=2 SV=1
Length = 341
Score = 87.4 bits (215), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 85/330 (25%), Positives = 147/330 (44%), Gaps = 48/330 (14%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R + + V + T E
Sbjct: 2 RKVVLITGASSGIGLALCKRLL---AEDDELHLCLACRNMSKAEAVCAALLASHPTAE-- 56
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
+ VD +N+ SV A +L Q+++ ++ ++NA ++ +P
Sbjct: 57 ----VTIVQVDVSNLQSVFRASKELKQRFQRLDCIYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKSKDEMGL--------------VFQANVFGPYYLIQKILPQ 168
++A+ + ++++ + S E GL VF+ NVFG + LI+++ P
Sbjct: 98 QLNIKALFFGLFSRKVIHMFSTAE-GLLTQGDKITADGLQEVFETNVFGHFILIRELEPL 156
Query: 169 L--SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI 226
L S + ++W SS A + SL+D + K Y SK DLL +A + QG+
Sbjct: 157 LCHSDNPSQLIWTSSRSARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGL 216
Query: 227 HQYVVQPGI-FTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATL 285
+ V PG T+ ++ F T M + L R + + + Y A V++
Sbjct: 217 YSNVACPGTALTNLTYGILPPFIWTLLMPAILLL-RFFANAF-TLTPYNGTEALVWLFHQ 274
Query: 286 INPHFEHQEVKYGSASSRDGMEYIETTDID 315
P + +KY SA++ G YI T +D
Sbjct: 275 -KPESLNPLIKYLSATTGFGRNYIMTQKMD 303
>sp|P56937|DHB7_HUMAN 3-keto-steroid reductase OS=Homo sapiens GN=HSD17B7 PE=1 SV=1
Length = 341
Score = 87.4 bits (215), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 85/330 (25%), Positives = 147/330 (44%), Gaps = 48/330 (14%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R + + V + T E
Sbjct: 2 RKVVLITGASSGIGLALCKRLL---AEDDELHLCLACRNMSKAEAVCAALLASHPTAE-- 56
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
+ VD +N+ SV A +L Q+++ ++ ++NA ++ +P
Sbjct: 57 ----VTIVQVDVSNLQSVFRASKELKQRFQRLDCIYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKSKDEMGL--------------VFQANVFGPYYLIQKILPQ 168
++A+ + ++++ + S E GL VF+ NVFG + LI+++ P
Sbjct: 98 QLNIKALFFGLFSRKVIHMFSTAE-GLLTQGDKITADGLQEVFETNVFGHFILIRELEPL 156
Query: 169 L--SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI 226
L S + ++W SS A + SL+D + K Y SK DLL +A + QG+
Sbjct: 157 LCHSDNPSQLIWTSSRSARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGL 216
Query: 227 HQYVVQPGI-FTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATL 285
+ V PG T+ ++ F T M + L R + + + Y A V++
Sbjct: 217 YSNVACPGTALTNLTYGILPPFIWTLLMPAILLL-RFFANAF-TLTPYNGTEALVWLFHQ 274
Query: 286 INPHFEHQEVKYGSASSRDGMEYIETTDID 315
P + +KY SA++ G YI T +D
Sbjct: 275 -KPESLNPLIKYLSATTGFGRNYIMTQKMD 303
>tr|Q2XQY1|Q2XQY1_MACFA 17-beta hydroxysteroid dehydrogenase 7 OS=Macaca fascicularis
GN=HSD17B7 PE=2 SV=1
Length = 341
Score = 87.0 bits (214), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 88/334 (26%), Positives = 149/334 (44%), Gaps = 56/334 (16%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R R E ++ +
Sbjct: 2 RKVVLITGASSGIGLALCKRLL---AEDDELHLCLACRN----RNKAEAVRASLLASHPT 54
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
V + VD +N+ SV A +L Q+++ ++ +VNA ++ +P
Sbjct: 55 AEVTI--VQVDISNLQSVFRASKELKQRFQRLDCIYVNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKSKDEMGL--------------VFQANVFGPYYLIQKILPQ 168
++A+ + ++++ + S E GL VF+ NVFG + LI+++ P
Sbjct: 98 QLNIKALFFGLFSRKVIHMFSTAE-GLLTQGDKITADGLQEVFETNVFGHFILIRELEPL 156
Query: 169 L--SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI 226
L S + ++W SS A + SL+D + K Y SK DLL +A + QG+
Sbjct: 157 LCHSDSPSQLIWTSSRNARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGL 216
Query: 227 HQYVVQPGI-FTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYV--- 282
+ VV PG T+ ++ F T M + L R + + + Y A V++
Sbjct: 217 YSNVVCPGTALTNLTYGILPPFIWTLLMPAILLL-RFFANAF-TLTPYNGTEALVWLFHQ 274
Query: 283 -ATLINPHFEHQEVKYGSASSRDGMEYIETTDID 315
+NP +KY SA++ G YI T +D
Sbjct: 275 KTESLNPL-----IKYLSATTGFGRNYIMTQKMD 303
>tr|A4RL41|A4RL41_MAGGR Putative uncharacterized protein OS=Magnaporthe grisea GN=MGG_01303
PE=4 SV=1
Length = 527
Score = 86.7 bits (213), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 98/402 (24%), Positives = 153/402 (38%), Gaps = 94/402 (23%)
Query: 15 NSNLGLNIAYRLIE----RQSADVRLTLVVTSRTLPRVREVVELIKKFV----------- 59
NS +G IA RLI+ ++S L L+VT+R+ + ++++++++K V
Sbjct: 55 NSGVGTGIAERLIDEFLVKRSLTSHLILIVTTRSKAKSQQIIDILRKHVRKAAEAKKLRG 114
Query: 60 --ATQEDPCS----VDFDYLLVDFTNMVSVLNAYYDLNQ--------------KYESINY 99
DP S + +LVD N+ SV A L + ++
Sbjct: 115 RAGPSYDPESTVARIHLVGILVDLCNLHSVYAAANLLKDGGSPAAGSNCPSSVRVPRLDS 174
Query: 100 FFVNAAQGVYDGIDWIG---------------------AVKQVLSDPLEAVTNPTYRKQL 138
+NA G + ++W G A K L DPL +
Sbjct: 175 IILNAGYGNWTSLNWWGLFVQLVTKGIPISFTWPAFKNAAKGTLVDPLTGRVLTKEQAIA 234
Query: 139 VGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKGK----------ATVVWISSIMADPKH 188
G S + +G F AN+FG Y +LP L + A ++W S+ P
Sbjct: 235 EGRTSAELLGETFTANLFGHYMFAHALLPLLRRSPEQLAEEALSPARIIWQGSVTVGPDE 294
Query: 189 LSLQDIEMIKSDVTYEGSKRVVDLL----------HLATYKQM------------KSQGI 226
S D + ++ Y+ KR+ D+L LAT + K
Sbjct: 295 YSTSDPQGLRHHDAYDYVKRLNDILVFSSTLPKPKPLATAYLLGEDNNDGKNNSDKLVAP 354
Query: 227 HQYVVQPGIFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLI 286
Y+ PGI + FA +G ++ YL R LGS WH Y +A +PV++A
Sbjct: 355 RMYLTHPGITNTAIFALPFTLSVIWG--WVMYLTRWLGSVWHVGSPYNSAFSPVWIALEE 412
Query: 287 NPHFEHQEV---KYGSASSR-DGMEYIETTDIDKTGSSDVLA 324
+ E K+GSA SR G + T+I G LA
Sbjct: 413 QSRLDDMEAHRSKWGSACSRWRGTLGAKKTEIHGWGWDGRLA 454
>sp|Q62904|DHB7_RAT 3-keto-steroid reductase OS=Rattus norvegicus GN=Hsd17b7 PE=1 SV=1
Length = 334
Score = 85.9 bits (211), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 80/329 (24%), Positives = 152/329 (46%), Gaps = 46/329 (13%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R L + V + + +A+
Sbjct: 2 RKVVLITGASSGIGLALCGRLL---AEDDDLHLCLACRNLSKAGAVRDAL---LASHP-- 53
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
S + + +D +N+ SV+ ++ ++++ ++Y ++NA ++ +P
Sbjct: 54 -SAEVSIVQMDVSNLQSVVRGAEEVKRRFQRLDYLYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKSKDEMGL-------------VFQANVFGPYYLIQKILPQL 169
L+A + + ++ + S E L VF+ N+FG + LI+++ P L
Sbjct: 98 QLNLKAFFCGIFSRNVIHMFSTAEGLLTQNDKITADGFQEVFETNLFGHFILIRELEPLL 157
Query: 170 --SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIH 227
S + ++W SS A + SL+DI+ K Y SK DLL++A + +G++
Sbjct: 158 CHSDNPSQLIWTSSRNAKKSNFSLEDIQHAKGQEPYSSSKYATDLLNVALNRNFNQKGLY 217
Query: 228 QYVVQPG-IFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLI 286
V PG + T+ ++ F T +L + +L R + + Y A A V++
Sbjct: 218 SSVTCPGVVMTNLTYGILPPFVWTL-LLPVIWLLRFFAHAF-TVTPYNGAEALVWLFHQ- 274
Query: 287 NPHFEHQEVKYGSASSRDGMEYIETTDID 315
P + KY S ++ G Y++ +D
Sbjct: 275 KPESLNPLTKYLSGTTGLGTNYVKGQKMD 303
>tr|Q9BDW7|Q9BDW7_RABIT 17-beta-hydroxysteroid dehydrogenase type 7 (Fragment)
OS=Oryctolagus cuniculus GN=HSD17B7 PE=2 SV=1
Length = 309
Score = 84.7 bits (208), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 84/330 (25%), Positives = 150/330 (45%), Gaps = 48/330 (14%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R + + + A
Sbjct: 2 RKVVLITGASSGIGLALCKRLL---TVDDGLHLCLACRNMGKAKAAR------AALLASH 52
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
+ VD ++ SV A +L Q+++ ++Y ++NA ++ +P
Sbjct: 53 SGAQVTMVQVDVGDLQSVFRAADELKQRFQRLDYVYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKSKDEMGL--------------VFQANVFGPYYLIQKILPQ 168
+ A+ + + ++++ + S E GL VF+ N+FG + LI+++ P
Sbjct: 98 QLNVRALFSGLFSRKVIHMFSTAE-GLLTQGDRLTADGLQEVFETNIFGHFILIRELEPL 156
Query: 169 L--SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGI 226
L S + ++W SS A + SL+DI+ K Y SK DLL++A + QG+
Sbjct: 157 LCHSDTPSRLIWTSSRNARKSNFSLEDIQHSKGQEPYSSSKYATDLLNVALNRHYNQQGL 216
Query: 227 HQYVVQPG-IFTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATL 285
+ VV PG + T+ ++ F T + F+ +L R + + + Y A V++
Sbjct: 217 YSSVVCPGTVLTNMTYGILPPFMWTLLLPFI-WLLRFFANAF-TLTPYNGAEVLVWLFHQ 274
Query: 286 INPHFEHQEVKYGSASSRDGMEYIETTDID 315
P + KY SA++ G YI T +D
Sbjct: 275 -KPESLNPLAKYMSATTGLGSNYITTQKMD 303
>tr|A8Q4L3|A8Q4L3_MALGO Putative uncharacterized protein OS=Malassezia globosa (strain ATCC
96807 / CBS 7966) GN=MGL_2564 PE=4 SV=1
Length = 383
Score = 84.0 bits (206), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 11/204 (5%)
Query: 70 FDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDPLEAV 129
D + +D ++ S + K + + +NA + G+DW+ A ++L++ +AV
Sbjct: 171 IDVVPLDLASLESTKACARTITAKVPYLTHIILNAGGAAWLGVDWLKATWEILTNLHKAV 230
Query: 130 TNPTYRKQLVGVKSKDEMGLVFQANVFGPYYLIQKILPQLSKG----KATVVWISSIMAD 185
T P+++ Q G KS D++G V+Q N G Y L +++ P L + V+W S+ A+
Sbjct: 231 TLPSFKLQRSGDKSSDDLGWVWQINAAGHYVLAKELEPLLCASPYATPSRVIWTGSLEAN 290
Query: 186 PKHLSLQDIEMIKSDVT---YEGSKRVVDLLHLATYKQMKSQG----IHQYVVQPGIFTS 238
QDI+ + + YE +K +LL L ++ S Y PGI +
Sbjct: 291 EADFHAQDIQCLDPQTSPRPYESTKYQCELLALGMDQRYTSSTQPHMPRAYTAHPGIVAT 350
Query: 239 YSFAKYLNFFTTFGMLFLFYLARL 262
F+ + M +FYL R+
Sbjct: 351 SIFSGVIPAIMMVLMKLVFYLVRI 374
>tr|B3RNM2|B3RNM2_9METZ Putative uncharacterized protein OS=Trichoplax adhaerens
GN=TRIADDRAFT_53215 PE=4 SV=1
Length = 301
Score = 75.1 bits (183), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 61/235 (25%), Positives = 112/235 (47%), Gaps = 18/235 (7%)
Query: 8 VAVITGANSNLGLNIAYRLI-ERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDPC 66
+ +ITGA + +G +A +L+ E Q R+T+ + R + + E++ +T +
Sbjct: 7 IVLITGATAGIGQELARQLVSEFQD---RITICLACRNIKKANATKEMLMSLCSTAK--- 60
Query: 67 SVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVK--QVLSD 124
D L + ++ SV+ ++ ++Y +N+ F+NA DW V + S
Sbjct: 61 ---VDILTLVTSDAKSVIAVAEEIKRRYSYLNHLFLNAGIMPITQFDWSHFVSGFRSFSS 117
Query: 125 PLEAVTNPTYRKQLVGVKSKDEMGL--VFQANVFGPYYLIQKILPQL--SKGKATVVWIS 180
+ T T ++ S GL VF N+FG Y LI ++ L S +VW S
Sbjct: 118 FINMFT--TGEGLIIQNDSVTNDGLQSVFATNLFGHYLLISELEDYLAASNKMTHIVWTS 175
Query: 181 SIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGI 235
S A+ SL +++ + Y SK +DLL+++ +++ S+GI+ +V PG+
Sbjct: 176 SSAANRASFSLDNMQHVNGKDPYGSSKHAIDLLNVSLNEKLNSKGIYSHVTCPGL 230
>tr|Q9N0M8|Q9N0M8_CALJA 17beta-hydroxysteroid dehydrogenase type 7 (Fragment) OS=Callithrix
jacchus PE=2 SV=1
Length = 323
Score = 74.7 bits (182), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 80/321 (24%), Positives = 142/321 (44%), Gaps = 46/321 (14%)
Query: 14 ANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDPCSVDFDYL 73
A+S +GL + RL+ D L L + R + + V + T E +
Sbjct: 1 ASSGIGLALCKRLLVE---DDELHLCLACRNMSKAEAVRAALLASHPTAE------VTVV 51
Query: 74 LVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP---LEAVT 130
VD +N+ SV A +L Q+++ + ++NA ++ +P ++A+
Sbjct: 52 QVDVSNLQSVFQASKELKQRFQRFDCIYLNAG---------------IMPNPHLNIKALF 96
Query: 131 NPTYRKQLV-------GVKSKDEM----GL--VFQANVFGPYYLIQKILPQL--SKGKAT 175
+ + + ++ G+ ++D+ GL VF+ NVFG + LI+++ P L S +
Sbjct: 97 SGLFSRNVIHMFSTAEGLLTQDDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQ 156
Query: 176 VVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQGIHQYVVQPGI 235
++W SS A + SL+D + K Y SK DLL +A + QG++ VV PG
Sbjct: 157 LIWTSSRNARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVVCPGT 216
Query: 236 -FTSYSFAKYLNFFTTFGMLFLFYLARLLGSKWHNIDGYKAANAPVYVATLINPHFEHQE 294
T+ ++ F T M + L R + + + Y A V++ P +
Sbjct: 217 ALTNLTYGVLPPFIWTLLMPAIL-LMRFFANAF-TLTPYNGTEALVWLFHQ-KPESLNPL 273
Query: 295 VKYGSASSRDGMEYIETTDID 315
+KY SA++ G YI T +D
Sbjct: 274 IKYLSATTGFGRNYITTQKMD 294
>tr|A6NH47|A6NH47_HUMAN Uncharacterized protein HSD17B7P2 OS=Homo sapiens GN=HSD17B7P2 PE=4
SV=2
Length = 262
Score = 69.7 bits (169), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 58/238 (24%), Positives = 107/238 (44%), Gaps = 42/238 (17%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R + + V + T E
Sbjct: 2 RKVVLITGASSGIGLALCKRLL---AEDDELHLCLACRNMSKAEAVCAALLASHPTAE-- 56
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
+ VD +N+ S A +L Q+++ ++ ++NA ++ +P
Sbjct: 57 ----VTIVQVDVSNLQSFFRASKELKQRFQRLDRIYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKS-------------KDEMGLVFQANVFGPYYLIQKILPQL 169
++A+ + ++++ + S D + VF+ +VFG + LI+++ P L
Sbjct: 98 QLNIKALLFGLFSRKVIHMFSTAEGLLTQGDKITADGLQEVFETDVFGHFILIRELEPLL 157
Query: 170 --SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQG 225
S + ++W SS A + SL+D + K Y SK DLL +A + + G
Sbjct: 158 CHSDNPSQLIWTSSRNARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFQPAG 215
>tr|Q9NRW5|Q9NRW5_HUMAN 17-beta-hydroxysteroid dehydrogenase type VII OS=Homo sapiens PE=2
SV=1
Length = 223
Score = 69.3 bits (168), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 60/239 (25%), Positives = 108/239 (45%), Gaps = 44/239 (18%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R + + V + T E
Sbjct: 2 RKVVLITGASSGIGLALCKRLL---AEDDELHLCLACRNMSKAEAVCAALLASHPTAE-- 56
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQKYESINYFFVNAAQGVYDGIDWIGAVKQVLSDP 125
+ VD +N+ S A +L Q+++ ++ ++NA ++ +P
Sbjct: 57 ----VTIVQVDVSNLQSFFRASKELKQRFQRLDRIYLNAG---------------IMPNP 97
Query: 126 ---LEAVTNPTYRKQLVGVKSKDEMGL--------------VFQANVFGPYYLIQKILPQ 168
++A+ + ++++ + S E GL VF+ +VFG + LI+++ P
Sbjct: 98 QLNIKALLFGLFSRKVIHMFSTAE-GLLTQGDKITADGLQEVFETDVFGHFILIRELEPL 156
Query: 169 L--SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMKSQG 225
L S + ++W SS A + SL+D + K Y SK DLL +A + + G
Sbjct: 157 LCHSDNPSQLIWTSSRNARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFQPAG 215
>tr|Q6IPC1|Q6IPC1_HUMAN HSD17B7P2 protein OS=Homo sapiens GN=HSD17B7P2 PE=2 SV=1
Length = 229
Score = 62.8 bits (151), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 46/238 (19%)
Query: 6 RKVAVITGANSNLGLNIAYRLIERQSADVRLTLVVTSRTLPRVREVVELIKKFVATQEDP 65
RKV +ITGA+S +GL + RL+ + D L L + R + + V + T E
Sbjct: 2 RKVVLITGASSGIGLALCKRLL---AEDDELHLCLACRNMSKAEAVCAALLASHPTAE-- 56
Query: 66 CSVDFDYLLVDFTNMVSVLNAYYDLNQ--KYESINYFFVNAAQGVYDGIDWIGAVKQVLS 123
+ VD +N+ S A +L Q +++ ++ ++NA ++
Sbjct: 57 ----VTIVQVDVSNLQSFFRASKELKQSCRFQRLDRIYLNAG---------------IMP 97
Query: 124 DP---LEAVTNPTYRKQLVGVKSKDEMGL--------------VFQANVFGPYYLIQKIL 166
+P ++A+ + ++++ + S E GL VF+ +VFG + LI+++
Sbjct: 98 NPQLNIKALLFGLFSRKVIHMFSTAE-GLLTQGDKITADGLQEVFETDVFGHFILIRELE 156
Query: 167 PQL--SKGKATVVWISSIMADPKHLSLQDIEMIKSDVTYEGSKRVVDLLHLATYKQMK 222
P L S + ++W SS A + SL+D + K Y SK DLL +A + +
Sbjct: 157 PLLCHSDNPSQLIWTSSRNARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFQ 214
BLASTP 2.2.18 [Mar-02-2008]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
URL: http://www.genolevures.org/elt/CAGL/CAGL0M11506p/sptr_blastp/CAGL0M11506p.html