CAGL0M09801p_blastp.html 
BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= CAGL0M09801p (infer) YLR285w : similar to uniprot|Q05874
Saccharomyces cerevisiae [Candida glabrata CBS 138]
         (256 letters)

Database: Genolevures3.aa 
           48,939 sequences; 23,992,848 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

|CAGL0M09801p (infer) YLR285w : similar to uniprot|Q05874 Sacchar...   528   e-150
|SAKL0A07986p (infer) YLR285W NNT1 Putative nicotinamide N- methy...   354   4e-98
|KLTH0G15092p (infer) YLR285W NNT1 Putative nicotinamide N- methy...   353   8e-98
|SACE0L13925p Putative nicotinamide N-methyltransferase, has a ro...   347   7e-96
|KLLA0C04708p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   328   3e-90
|ZYRO0D14542p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   327   7e-90
|ERGO0G14674p Syntenic homolog of Saccharomyces cerevisiae YLR285...   322   3e-88
|DEHA2F21604p (infer) YLR285W NNT1 Putative nicotinamide N-methyl...   266   2e-71
|YALI0A09636p (infer) YLR285w NNT1 nicotinamide N-methyltransfera...   216   3e-56


>|CAGL0M09801p (infer) YLR285w : similar to uniprot|Q05874 Saccharomyces
           cerevisiae [Candida glabrata CBS 138]
          Length = 256

 Score =  528 bits (1360), Expect = e-150,   Method: Compositional matrix adjust.
 Identities = 256/256 (100%), Positives = 256/256 (100%)

Query: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60
           MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG
Sbjct: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60

Query: 61  HLLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMA 120
           HLLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMA
Sbjct: 61  HLLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMA 120

Query: 121 NIQYNVNTIIPDELKENVRVEGYIWGNEYDPLTIHLDGDKKFDLIILSDLVFNHNQHDKL 180
           NIQYNVNTIIPDELKENVRVEGYIWGNEYDPLTIHLDGDKKFDLIILSDLVFNHNQHDKL
Sbjct: 121 NIQYNVNTIIPDELKENVRVEGYIWGNEYDPLTIHLDGDKKFDLIILSDLVFNHNQHDKL 180

Query: 181 LQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEKIEMVNWKPMFEEDEE 240
           LQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEKIEMVNWKPMFEEDEE
Sbjct: 181 LQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEKIEMVNWKPMFEEDEE 240

Query: 241 TAEVRSRVYAYYMTHA 256
           TAEVRSRVYAYYMTHA
Sbjct: 241 TAEVRSRVYAYYMTHA 256


>|SAKL0A07986p (infer) YLR285W NNT1 Putative nicotinamide N- methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           highly similar to uniprot|Q05874 Saccharomyces
           cerevisiae [Lachancea kluyveri]
          Length = 270

 Score =  354 bits (909), Expect = 4e-98,   Method: Compositional matrix adjust.
 Identities = 181/270 (67%), Positives = 208/270 (77%), Gaps = 16/270 (5%)

Query: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60
           MSDTESL +   LF+EPEDF    P+ H+A YER  V   S S +  +KL+LVGSSPLWG
Sbjct: 1   MSDTESLIEG-SLFEEPEDFNKPPPQPHFATYERTTVSPQSNSLVKEVKLRLVGSSPLWG 59

Query: 61  HLLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMA 120
           HLLWNAGIYT RHLD+   LV +K VLELGAA ALPS++ GLIGA + VVTD+PDADL+ 
Sbjct: 60  HLLWNAGIYTGRHLDENIGLVKDKTVLELGAAGALPSIICGLIGASKVVVTDFPDADLLQ 119

Query: 121 NIQYNVNTII--PDEL-------------KENVRVEGYIWGNEYDPLTIHLDGDKKFDLI 165
           NIQYNV+  I   +EL             + +V VEGYIWGN+Y+PL  H+   KKFDLI
Sbjct: 120 NIQYNVDHQIYQGNELPADGDDARDQELQRRDVVVEGYIWGNDYEPLVKHIGSGKKFDLI 179

Query: 166 ILSDLVFNHNQHDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEK 225
           ILSDLVFNH++H KLL TTKDLLA +GKALVVFSPHRP LL ADLQFFET KE+GL PEK
Sbjct: 180 ILSDLVFNHSEHAKLLNTTKDLLAKDGKALVVFSPHRPWLLNADLQFFETAKEHGLKPEK 239

Query: 226 IEMVNWKPMFEEDEETAEVRSRVYAYYMTH 255
           IEMVNWKPMFEEDEETAE+RSRVYAYY+TH
Sbjct: 240 IEMVNWKPMFEEDEETAEIRSRVYAYYLTH 269


>|KLTH0G15092p (infer) YLR285W NNT1 Putative nicotinamide N- methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Kluyveromyces thermotolerans]
          Length = 266

 Score =  353 bits (907), Expect = 8e-98,   Method: Compositional matrix adjust.
 Identities = 178/267 (66%), Positives = 207/267 (77%), Gaps = 12/267 (4%)

Query: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60
           MSDTES      +F EPE +   +P+ H+A Y R  VP  SKS+   ++L+LVGSSPLWG
Sbjct: 1   MSDTESFIQG-DIFAEPEGYFQAEPEAHFAEYVREQVPSASKSQKKEVRLRLVGSSPLWG 59

Query: 61  HLLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMA 120
           HLLWNAGIYTA HLDK+P+LV ++ VLELGAA ALPS+VAG+IGAK+ VVTDYPDADL+ 
Sbjct: 60  HLLWNAGIYTANHLDKFPDLVKDRCVLELGAAGALPSVVAGMIGAKKCVVTDYPDADLLQ 119

Query: 121 NIQYNVNTIIPD----------ELKENVRVEGYIWGNEYDPLTIHLD-GDKKFDLIILSD 169
           NIQYNV+  + D            + NV VEGYIWGN+Y PL  HL  G  KFDL+ILSD
Sbjct: 120 NIQYNVDHEVFDGEALPSDGAGASERNVVVEGYIWGNDYAPLVSHLPCGTTKFDLVILSD 179

Query: 170 LVFNHNQHDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEKIEMV 229
           LVFNH +H KLLQTTKDLLA +GKALVVFSPHRP LL  DLQFFET K++ L PEKIEMV
Sbjct: 180 LVFNHTEHLKLLQTTKDLLAQDGKALVVFSPHRPWLLNDDLQFFETAKDFALVPEKIEMV 239

Query: 230 NWKPMFEEDEETAEVRSRVYAYYMTHA 256
           NWKPMFEEDEET+E+RSRVYAYY+THA
Sbjct: 240 NWKPMFEEDEETSEIRSRVYAYYLTHA 266


>|SACE0L13925p Putative nicotinamide N-methyltransferase, has a role in rDNA
           silencing and in lifespan determination [Saccharomyces
           cerevisiae]
          Length = 261

 Score =  347 bits (890), Expect = 7e-96,   Method: Compositional matrix adjust.
 Identities = 170/260 (65%), Positives = 202/260 (77%), Gaps = 6/260 (2%)

Query: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60
           MSD ESL +A GLF+EPEDF P  PK H+A Y+R  +   SKS + ++KL+LVG+SPLWG
Sbjct: 1   MSDIESLGEAAGLFEEPEDFLPPPPKPHFAEYQRSHITKESKSDVKDIKLRLVGTSPLWG 60

Query: 61  HLLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMA 120
           HLLWNAGIYTA HLD +PEL+  K VLELGAA+ALPS++  L GA+  V TDYPD DLM 
Sbjct: 61  HLLWNAGIYTANHLDSHPELIKGKTVLELGAAAALPSVICALNGAQMVVSTDYPDPDLMQ 120

Query: 121 NIQYNVNTIIPDELKENVRVEGYIWGNEYDPLTIHLD----GDKKFDLIILSDLVFNHNQ 176
           NI YN+ + +P++   NV  EGYIWGN+Y PL  H++     + KFDLIILSDLVFNH +
Sbjct: 121 NIDYNIKSNVPEDFN-NVSTEGYIWGNDYSPLLAHIEKIGNNNGKFDLIILSDLVFNHTE 179

Query: 177 HDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCK-EYGLTPEKIEMVNWKPMF 235
           H KLLQTTKDLLA  G+ALVVFSPHRP LLE DL+FFE  K E+ L P+ IEMVNWKPMF
Sbjct: 180 HHKLLQTTKDLLAEKGQALVVFSPHRPKLLEKDLEFFELAKNEFHLVPQLIEMVNWKPMF 239

Query: 236 EEDEETAEVRSRVYAYYMTH 255
           +EDEET EVRSRVYAYY+TH
Sbjct: 240 DEDEETIEVRSRVYAYYLTH 259


>|KLLA0C04708p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Kluyveromyces lactis NRRL Y-1140]
          Length = 270

 Score =  328 bits (842), Expect = 3e-90,   Method: Compositional matrix adjust.
 Identities = 165/270 (61%), Positives = 204/270 (75%), Gaps = 16/270 (5%)

Query: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60
           MSD ESLN    LF EP DF    P+ H+A Y R DVP+ S S+  ++KL+LVGSSPLWG
Sbjct: 1   MSDIESLNGG-DLFAEPSDFYKPPPEPHFATYTRDDVPESSTSQQKDIKLRLVGSSPLWG 59

Query: 61  HLLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMA 120
           HLLWNAGIYTA+H+D +PE V +K VLELGAA ALP+++AGL+GA++ V TDYPDADL++
Sbjct: 60  HLLWNAGIYTAKHMDSHPEEVQDKLVLELGAAGALPTIIAGLLGARKVVSTDYPDADLIS 119

Query: 121 NIQYNVN-------TIIPDELKEN-------VRVEGYIWGNEYDPLTIHLDGD-KKFDLI 165
           NIQYNV+        +  DE K +       V VEGYIWGN+Y+P+  HL  D +KFDLI
Sbjct: 120 NIQYNVDHNIYGGEELFKDEEKRSKQMANRKVVVEGYIWGNDYEPILKHLPQDQQKFDLI 179

Query: 166 ILSDLVFNHNQHDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEK 225
           ILSDLVFNH +H KL +TTKDLL  NGKALVVFSPHRP LLE DL FF+ C+E+GL  + 
Sbjct: 180 ILSDLVFNHTEHAKLFKTTKDLLRENGKALVVFSPHRPWLLENDLAFFKDCEEFGLKSDL 239

Query: 226 IEMVNWKPMFEEDEETAEVRSRVYAYYMTH 255
           IE+ +WKPMF+EDEET E+RS +YAYY++H
Sbjct: 240 IELTHWKPMFDEDEETVEIRSSIYAYYLSH 269


>|ZYRO0D14542p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase has
           a role in rDNA silencing and in lifespan determination :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Zygosaccharomyces rouxii]
          Length = 263

 Score =  327 bits (838), Expect = 7e-90,   Method: Compositional matrix adjust.
 Identities = 163/263 (61%), Positives = 196/263 (74%), Gaps = 9/263 (3%)

Query: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60
           MSD E L+ A G+F+EP DF P  P+ H+A+YER  V   S S+   ++L+LVG SPLWG
Sbjct: 1   MSDNE-LDGAFGVFEEPTDFLPPPPEAHFADYEREYVSKESDSQNKKVQLRLVGKSPLWG 59

Query: 61  HLLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMA 120
           H+LWNAGIYTA+HLDK+P LV  KNVLELGAA+ALP++V GLIGA + V TDYP+ +L+ 
Sbjct: 60  HMLWNAGIYTAKHLDKHPGLVKGKNVLELGAAAALPTVVCGLIGANKVVSTDYPEPELIQ 119

Query: 121 NIQYNVN-------TIIPDELKENVRVEGYIWGNEYDPLTIHLDGDKKFDLIILSDLVFN 173
           NIQYNV+           D     V VEGYIWGNEY+P+  H  G  KFDLIILSD VFN
Sbjct: 120 NIQYNVDHELYGGKPFSQDSNDRKVVVEGYIWGNEYEPILSHT-GGSKFDLIILSDCVFN 178

Query: 174 HNQHDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEKIEMVNWKP 233
           H +H KLL+  KDLLA +GKALVVFSPHRP LL+ DL FFET KE+GL PE I++V W P
Sbjct: 179 HTEHRKLLRCIKDLLANDGKALVVFSPHRPRLLDVDLSFFETAKEFGLAPEFIDLVKWHP 238

Query: 234 MFEEDEETAEVRSRVYAYYMTHA 256
           MF+ED  TAE+RSRVYAYY+THA
Sbjct: 239 MFDEDPSTAEIRSRVYAYYLTHA 261


>|ERGO0G14674p Syntenic homolog of Saccharomyces cerevisiae YLR285W (NNT1)
           [Eremothecium gossypii]
          Length = 265

 Score =  322 bits (825), Expect = 3e-88,   Method: Compositional matrix adjust.
 Identities = 164/260 (63%), Positives = 192/260 (73%), Gaps = 7/260 (2%)

Query: 3   DTESLNDALGLFDEPEDFRPEKPKE-HYANYERIDVPDISKSKITNLKLQLVGSSPLWGH 61
           + +SL  A  LF EP+ F  EKP E H+A YER  VP  S  + T ++++LVGSSPLWGH
Sbjct: 6   EEDSLYGATELFGEPDGFY-EKPAESHFAEYERSAVPAQSARRDTQVRIRLVGSSPLWGH 64

Query: 62  LLWNAGIYTARHLDKYPELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLMAN 121
           LLWN+ IYTARHLD +PE V  + VLELGAA ALPSLVAGL+GA++ V TDYPDADL+ N
Sbjct: 65  LLWNSAIYTARHLDAHPEQVVGRCVLELGAAGALPSLVAGLLGARQVVATDYPDADLVGN 124

Query: 122 IQYNVNTII----PDELKENVRVEGYIWGNEYDPLTIHL-DGDKKFDLIILSDLVFNHNQ 176
           IQYNV+ +I    P     +V VEGYIWGN+Y PL  HL  G   FDL++LSDLVFNH +
Sbjct: 125 IQYNVDHVIYGGKPPTEAPHVAVEGYIWGNDYGPLRRHLPPGQTGFDLVLLSDLVFNHTE 184

Query: 177 HDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEKIEMVNWKPMFE 236
           H KLLQTT+DLLA  G+ALVVFSPHRP LLE DLQFFET  EYGL  E IE V W PMF 
Sbjct: 185 HHKLLQTTRDLLAPAGRALVVFSPHRPWLLEKDLQFFETAAEYGLRAELIEQVTWAPMFA 244

Query: 237 EDEETAEVRSRVYAYYMTHA 256
           +D   AEVR+RVYAYY+TH 
Sbjct: 245 DDPGPAEVRARVYAYYLTHC 264


>|DEHA2F21604p (infer) YLR285W NNT1 Putative nicotinamide N-methyltransferase :
           similar to uniprot|Q05874 Saccharomyces cerevisiae
           [Debaryomyces hansenii CBS767]
          Length = 254

 Score =  266 bits (679), Expect = 2e-71,   Method: Compositional matrix adjust.
 Identities = 135/259 (52%), Positives = 182/259 (70%), Gaps = 13/259 (5%)

Query: 1   MSDTESLNDALGLFDEPEDFRPEKPKEHYANYERIDVPDISKSKITNLKLQLVGSSPLWG 60
           MSD E ++   GLF EPE F P  P  H+A Y+R      +K+    L L+LVG SPLWG
Sbjct: 1   MSDDEFID--TGLFAEPEGFTPPPPPPHFAKYQRK-----NKTDPAELNLRLVGKSPLWG 53

Query: 61  HLLWNAGIYTARHLDKYP-ELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDADLM 119
           HLLWNAG++TA +LDK+  ELV+ K+VLELGAA+ LPSL+ G+    R V TDYPD DL+
Sbjct: 54  HLLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLI 113

Query: 120 ANIQYNVNTIIPDELKENVRVEGYIWGNEYDPLT----IHLDGDKKFDLIILSDLVFNHN 175
           +NIQ+N +     +L + V V+G+IWG +  PL       +  + KFDL+ILSDLVFNH 
Sbjct: 114 SNIQHNFDHCQGLDLSKTV-VKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSDLVFNHT 172

Query: 176 QHDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCKEYGLTPEKIEMVNWKPMF 235
           +H KLL+T +D +  NGK LVVFSPHRP LLE DL+FF TC+++    EKI++V WKPMF
Sbjct: 173 EHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKIDLVTWKPMF 232

Query: 236 EEDEETAEVRSRVYAYYMT 254
           EED+E+ ++R+RVY++++ 
Sbjct: 233 EEDDESIDIRARVYSFFLV 251


>|YALI0A09636p (infer) YLR285w NNT1 nicotinamide N-methyltransferase : similar to
           uniprot|Q05874 Saccharomyces cerevisiae [Yarrowia
           lipolytica CLIB122]
          Length = 273

 Score =  216 bits (549), Expect = 3e-56,   Method: Compositional matrix adjust.
 Identities = 126/273 (46%), Positives = 172/273 (63%), Gaps = 22/273 (8%)

Query: 1   MSDTESLNDALGLFDEPEDF-RPEKP--KEHYANYERIDVPDISKSKITNLKLQLVGSSP 57
           MSD E L    GLFDEP+DF +PE+    + YA  E+  V      + TN  L+L   +P
Sbjct: 1   MSDIEDLASG-GLFDEPKDFYKPEEQPGSDSYARQEK-HVAASEYKEPTNFNLRLTAKNP 58

Query: 58  LWGHLLWNAGIYTARHLDKYP-ELVSNKNVLELGAASALPSLVAGLIGAKRAVVTDYPDA 116
           LWGHLLWNAG  T+ +LD++  ELV  K V+E GA + LPSL+   +GAK+ V+TDYPDA
Sbjct: 59  LWGHLLWNAGKVTSDYLDEHSKELVEGKKVIEFGAGAGLPSLLCHAVGAKQVVITDYPDA 118

Query: 117 DLMANIQYNVNTIIPDELKEN--------------VRVEGYIWGNEYDPLTIHLDGDKKF 162
           DL+ N++YNV+ +  D   +N              ++VEG+IWGN+   L I + G   +
Sbjct: 119 DLLYNLKYNVDQLKKDWDAKNADFSGPSPCADVSSMKVEGFIWGNDASEL-IEMSGGTGY 177

Query: 163 DLIILSDLVFNHNQHDKLLQTTKDLLATNGKALVVFSPHRPHLLEADLQFFETCK-EYGL 221
           DL+ILSD+VFNH++H KL+++ K+LLA  GK  VVF+PHR  L   DL FF   K E G 
Sbjct: 178 DLVILSDVVFNHSEHAKLVRSAKELLAPGGKVFVVFTPHRAKLFNEDLDFFRRAKDEAGF 237

Query: 222 TPEKIEMVNWKPMFEEDEETAEVRSRVYAYYMT 254
             EK+  + + PMFEE+EET E+RS V+ Y +T
Sbjct: 238 ESEKLFELKYYPMFEEEEETKELRSMVFGYMLT 270



BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.