CAGL0C01221p_blastp.html 
BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= CAGL0C01221p (infer) YDR211w GCD6 : highly similar to
uniprot|P32501 Saccharomyces cerevisiae [Candida glabrata CBS 138]
         (717 letters)

Database: Genolevures3.aa 
           48,939 sequences; 23,992,848 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

|CAGL0C01221p (infer) YDR211w GCD6 : highly similar to uniprot|P3...  1490   0.0  
|SACE0D09856p Catalytic epsilon subunit of the translation initia...  1046   0.0  
|SAKL0H13090p (infer) YDR211W GCD6 Catalytic epsilon subunit of t...   939   0.0  
|ZYRO0A09284p (infer) YDR211W GCD6 Catalytic epsilon subunit of t...   937   0.0  
|KLTH0F07942p (infer) YDR211W GCD6 Catalytic epsilon subunit of t...   936   0.0  
|KLLA0A04235p (infer) YDR211W GCD6 Catalytic epsilon subunit of t...   904   0.0  
|ERGO0G06292p Syntenic homolog of Saccharomyces cerevisiae YDR211...   873   0.0  
|DEHA2G14322p (infer) YDR211W GCD6 Catalytic epsilon subunit of t...   729   0.0  
|YALI0B15708p (infer) YDR211w GCD6 translation initiation factor ...   504   e-142
|YALI0C06490p (infer) CaPSA1 Mannose-1-phosphate guanyltransferas...    64   8e-10
|YALI0E21846p (infer) YOR260w GCD1 translation initiation factor ...    64   9e-10
|DEHA2E15862p (infer) YDL055C PSA1 GDP-mannose pyrophosphorylase ...    59   2e-08


>|CAGL0C01221p (infer) YDR211w GCD6 : highly similar to uniprot|P32501
           Saccharomyces cerevisiae [Candida glabrata CBS 138]
          Length = 717

 Score = 1490 bits (3858), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 717/717 (100%), Positives = 717/717 (100%)

Query: 1   MAGKKGKGVPPKKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEYTL 60
           MAGKKGKGVPPKKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEYTL
Sbjct: 1   MAGKKGKGVPPKKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEYTL 60

Query: 61  EFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDN 120
           EFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDN
Sbjct: 61  EFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDN 120

Query: 121 RGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTIEPAC 180
           RGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTIEPAC
Sbjct: 121 RGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTIEPAC 180

Query: 181 FVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTPHVPP 240
           FVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTPHVPP
Sbjct: 181 FVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTPHVPP 240

Query: 241 IFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLGRLCY 300
           IFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLGRLCY
Sbjct: 241 IFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLGRLCY 300

Query: 301 PLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVIGR 360
           PLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVIGR
Sbjct: 301 PLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVIGR 360

Query: 361 NCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVIEDNK 420
           NCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVIEDNK
Sbjct: 361 NCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVIEDNK 420

Query: 421 EIPAGSKISSVPVASSRSRLPASDGYDDEDDDEEYSETFDDTTQQALASELVGEHGVGYV 480
           EIPAGSKISSVPVASSRSRLPASDGYDDEDDDEEYSETFDDTTQQALASELVGEHGVGYV
Sbjct: 421 EIPAGSKISSVPVASSRSRLPASDGYDDEDDDEEYSETFDDTTQQALASELVGEHGVGYV 480

Query: 481 YESDASDIEEYDEDECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNSVYTDRE 540
           YESDASDIEEYDEDECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNSVYTDRE
Sbjct: 481 YESDASDIEEYDEDECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNSVYTDRE 540

Query: 541 DYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLATATALV 600
           DYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLATATALV
Sbjct: 541 DYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLATATALV 600

Query: 601 RRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQKFEKPEF 660
           RRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQKFEKPEF
Sbjct: 601 RRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQKFEKPEF 660

Query: 661 ILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKWVDWLRNAEEESDDE 717
           ILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKWVDWLRNAEEESDDE
Sbjct: 661 ILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKWVDWLRNAEEESDDE 717


>|SACE0D09856p Catalytic epsilon subunit of the translation initiation factor
           eIF2B, the guanine-nucleotide exchange factor for eIF2;
           activity subsequently regulated by phosphorylated eIF2;
           first identified as a negative regulator of GCN4
           expression [Saccharomyces cerevisiae]
          Length = 712

 Score = 1046 bits (2704), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 507/715 (70%), Positives = 601/715 (84%), Gaps = 15/715 (2%)

Query: 1   MAGKKGKGVPP----KKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLI 56
           MAGKKG+         KN DMDVEDRLQAVVLTDSYETRFMPLTA KPRCL+PLANVPLI
Sbjct: 1   MAGKKGQKKSGLGNHGKNSDMDVEDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLI 60

Query: 57  EYTLEFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMR 116
           EYTLEFLAKAG  EVFL CS+HA Q+++YIE SKWNLPWSPFK+TT+M+PEAR  GDVMR
Sbjct: 61  EYTLEFLAKAGVHEVFLICSSHANQINDYIENSKWNLPWSPFKITTIMSPEARCTGDVMR 120

Query: 117 DLDNRGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTI 176
           DLDNRGIITGDFILVSGDV+TNIDFSKML FHK+MH +DKDHI+TMCL+KAS Y  TRTI
Sbjct: 121 DLDNRGIITGDFILVSGDVLTNIDFSKMLEFHKKMHLQDKDHISTMCLSKASTYPKTRTI 180

Query: 177 EPACFVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTP 236
           EPA FVL+KST+RC+YYQD+P P+SR +  + +DPELL+NVD F +RNDLIDCRIDICT 
Sbjct: 181 EPAAFVLDKSTSRCIYYQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRIDICTS 240

Query: 237 HVPPIFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLG 296
           HVP IFQ+NFDYQSLR+DF+KGVISSD+LGKHIYAY+TDEYAVR ESW ++DTISQDFLG
Sbjct: 241 HVPLIFQENFDYQSLRTDFVKGVISSDILGKHIYAYLTDEYAVRVESWQTYDTISQDFLG 300

Query: 297 RLCYPLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENC 356
           R CYPLVL+SNIQ+DQTYSYES HIYKEKDVVLAQSCKIGKCTAIG+GTKIGE T +EN 
Sbjct: 301 RWCYPLVLDSNIQDDQTYSYESRHIYKEKDVVLAQSCKIGKCTAIGSGTKIGEGTKIENS 360

Query: 357 VIGRNCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVI 416
           VIGRNC IGENI IKNS+IWD+ +IGN   I H ++ASN  +G+NV LNDGCIIGF+V I
Sbjct: 361 VIGRNCQIGENIRIKNSFIWDDCIIGNNSIIDHSLIASNATLGSNVRLNDGCIIGFNVKI 420

Query: 417 EDNKEIPAGSKISSVPVASSRSRLPASDGYDDEDDDEEYSETFDDTTQQALASELVGEHG 476
           +DN ++   +KIS+ P+ ++ SR+     YD+E  +E++ +  DD   Q LA  +VG+ G
Sbjct: 421 DDNMDLDRNTKISASPLKNAGSRM-----YDNE-SNEQFDQDLDD---QTLAVSIVGDKG 471

Query: 477 VGYVYESDASDIEEYDEDECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNSVY 536
           VGY+YES+ SD E+   + C K +N+L  Q++++YLSD+SISS  ++TKK+RTMS NS+Y
Sbjct: 472 VGYIYESEVSDDEDSSTEAC-KEINTLSNQLDELYLSDDSISSATKKTKKRRTMSVNSIY 530

Query: 537 TDREDYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLATA 596
           TDRE+ +  E E EDF  EGIATVERA+EN+HDLDTALLELNTLRMSMNVTYHEVR+AT 
Sbjct: 531 TDREE-IDSEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSMNVTYHEVRIATI 589

Query: 597 TALVRRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQKFE 656
           TAL+RRVYHFI TQTLGPK+AV KVF QWG LF RQ F+ EEY+DLMNI+ME I EQ F+
Sbjct: 590 TALLRRVYHFIATQTLGPKDAVVKVFNQWGLLFKRQAFDEEEYIDLMNIIMEKIVEQSFD 649

Query: 657 KPEFILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKWVDWLRNAE 711
           KP+ ILFSAL +LYDNDI+EED IY+WWDNVS D +YD+VK LT KWV+WL+NA+
Sbjct: 650 KPDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYDEVKKLTVKWVEWLQNAD 704


>|SAKL0H13090p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
           initiation factor eIF2B the guanine-nucleotide exchange
           factor for eIF2 activity subsequently regulated by
           phosphorylated eIF2 first identified as a negative
           regulator of GCN4 expression : similar to uniprot|P32501
           Saccharomyces cerevisiae [Lachancea kluyveri]
          Length = 727

 Score =  939 bits (2427), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 468/715 (65%), Positives = 574/715 (80%), Gaps = 10/715 (1%)

Query: 1   MAGKKGK----GVPPKKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLI 56
           MAGKK K    G    K  ++  ++RLQA+VLTDS+ETRFMPLT+ KPRCL+PLANVPLI
Sbjct: 1   MAGKKNKSHNNGSKHGKKTELVQDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANVPLI 60

Query: 57  EYTLEFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMR 116
           EYTLEFLAKAG +EV+L C++HA+QV+EYIE SKWNLPWSPFKV+T+M+ E+RS+GD MR
Sbjct: 61  EYTLEFLAKAGVNEVYLICASHAEQVNEYIENSKWNLPWSPFKVSTIMSLESRSVGDAMR 120

Query: 117 DLDNRGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTI 176
           DLDNRG+ITGDFILVSGD+VTN++F K L  H++  A DKDHI TMCL+KASQY+ TR+ 
Sbjct: 121 DLDNRGLITGDFILVSGDLVTNMEFDKALEAHRKQRATDKDHIVTMCLSKASQYHRTRSY 180

Query: 177 EPACFVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTP 236
           EP+ F+ +KS NRCLYYQ++P  +S+ +  + +DPELLE+V+ F++RNDLIDC +DIC+P
Sbjct: 181 EPSTFIFDKSNNRCLYYQEIPPASSKKKTAVAIDPELLEDVEEFTLRNDLIDCYVDICSP 240

Query: 237 HVPPIFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLG 296
            VP IFQ+NFDYQ LR DF+KGV+SSDLL KHIYAYITDEYA RAESW ++D ISQDFL 
Sbjct: 241 LVPAIFQENFDYQYLRKDFVKGVLSSDLLKKHIYAYITDEYAARAESWQTYDAISQDFLA 300

Query: 297 RLCYPLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENC 356
           R CYPLVL SN+ EDQ+YSYES HIYKEKDVVLAQSCKIGKCTAIG+G+KIGE T +EN 
Sbjct: 301 RWCYPLVLNSNLLEDQSYSYESQHIYKEKDVVLAQSCKIGKCTAIGSGSKIGEGTNIENS 360

Query: 357 VIGRNCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVI 416
           VIGRNC IGENI I+NSY+WDN VI +   + H IVASNT++G NV LNDGCIIGF+VVI
Sbjct: 361 VIGRNCQIGENITIRNSYVWDNAVIMDDSILKHSIVASNTRIGKNVTLNDGCIIGFNVVI 420

Query: 417 EDNKEIPAGSKISSVPVASSRSRLPASDGYDDEDDDEEYSETFDDTTQQALASELVGEHG 476
           +DNK IP G KIS  PV  S S+   ++ Y D  DDEE  E  ++    A A +LVGE+G
Sbjct: 421 DDNKIIPEGCKISGTPVEKS-SQFLDTESYIDSSDDEENEEGMEEDV--APARDLVGENG 477

Query: 477 VGYVYESDASDIEEYDEDECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNSVY 536
           +GY+YES+ SD E+   D    + N+L  +++++YLSD SISS   + KKKRTMST S+Y
Sbjct: 478 IGYLYESEYSDDEDDTTDG-DHVTNTLSYKLDELYLSDTSISSATTKHKKKRTMSTTSLY 536

Query: 537 TDREDYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLATA 596
           TD+E    D ++ EDF  E IATV RA+EN+HDLDTALLELNTLRMSMNVTYHEVR +T 
Sbjct: 537 TDKE--DDDLDDEEDFEKEAIATVARAMENNHDLDTALLELNTLRMSMNVTYHEVRTSTV 594

Query: 597 TALVRRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQKFE 656
            A++RRVYHFI TQTLGPK+AV KVF QWG LF RQ F+ EE +DL+NI+ME + E+ FE
Sbjct: 595 IAMLRRVYHFIATQTLGPKDAVTKVFAQWGLLFKRQAFDQEESVDLVNIIMEGVVEENFE 654

Query: 657 KPEFILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKWVDWLRNAE 711
           KP+FILFSALN LYD DIL+ED IY+WWD VS+D KY++VK LT KWV+WL+NA+
Sbjct: 655 KPDFILFSALNCLYDMDILDEDVIYQWWDTVSKDIKYEEVKKLTEKWVEWLKNAD 709


>|ZYRO0A09284p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
           initiation factor eIF2B the guanine-nucleotide exchange
           factor for eIF2 activity subsequently regulated by
           phosphorylated eIF2 first identified as a negative
           regulator of GCN4 expression : similar to uniprot|P32501
           Saccharomyces cerevisiae [Zygosaccharomyces rouxii]
          Length = 718

 Score =  937 bits (2421), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 448/717 (62%), Positives = 560/717 (78%), Gaps = 24/717 (3%)

Query: 1   MAGKKGKGVPPKKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEYTL 60
           MAGKK K  P    ++M  +DRLQA+VLTDS+ETRFMPL+  KPRCL+PLANVPL+EYTL
Sbjct: 1   MAGKKIKAHP---KEEMVQDDRLQAIVLTDSFETRFMPLSNDKPRCLLPLANVPLLEYTL 57

Query: 61  EFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDN 120
           EFLAKA   EV+L CSAHA  + +YIE SKW+ PWSPFKV T+M+PEARS+GD MRDLDN
Sbjct: 58  EFLAKAPVKEVYLVCSAHATLISDYIEASKWSFPWSPFKVFTIMSPEARSVGDAMRDLDN 117

Query: 121 RGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTIEPAC 180
           +G+I GDF+L+SGD VTN+DF K   FHK MHAKDKDHI T CL+KA+Q++ TR  EPA 
Sbjct: 118 KGVIAGDFVLMSGDAVTNLDFDKFWDFHKRMHAKDKDHIVTTCLSKATQFHRTRAFEPAS 177

Query: 181 FVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTPHVPP 240
           F+L+KS NRCLYYQ++P P+SR +  +++DP+LLE VD F +RNDLIDCRIDIC+P VP 
Sbjct: 178 FILDKSDNRCLYYQEIPLPSSRVKTSVEIDPDLLEGVDEFVLRNDLIDCRIDICSPLVPA 237

Query: 241 IFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLGRLCY 300
           IFQ+NFDYQ LRSDF+KGV+SSDLL KH+YAYIT+EYA R ESW S+D+ISQDF+GR CY
Sbjct: 238 IFQENFDYQMLRSDFIKGVLSSDLLRKHVYAYITEEYAARVESWQSYDSISQDFIGRWCY 297

Query: 301 PLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVIGR 360
           PLVL+SN+  DQTYSYES HIYKE+ VVLAQSCKIGKCTAIG+ TKIGE  +VENCVIGR
Sbjct: 298 PLVLDSNLMPDQTYSYESNHIYKEQGVVLAQSCKIGKCTAIGSRTKIGESALVENCVIGR 357

Query: 361 NCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVIEDNK 420
           NC IG    I++S+IWDNTVIGN   I+H IVAS TK+G NV+LNDGCIIGF+VVIED K
Sbjct: 358 NCYIGSGAVIRDSHIWDNTVIGNNSVINHSIVASGTKLGTNVVLNDGCIIGFNVVIEDGK 417

Query: 421 EIPAGSKISSVPVASSR------SRLPASDGYDDEDDDEEYSETFDDTTQQALASELVGE 474
           E+P G +++  PV  S       S     +   ++D+ E             +A EL G 
Sbjct: 418 ELPRGVRVNGTPVKDSEDNAFGLSDEEDEEETPEKDNPE-------------IAFELCGT 464

Query: 475 HGVGYVYESDASDIEEYDEDECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNS 534
            G GY+YE   S+ +E+D     ++V+ L  +++++YLSD+SISS   ++KKKRTMSTNS
Sbjct: 465 KGRGYIYEDPLSE-DEHDLPIGEEMVSGLSHRLDEVYLSDSSISSVT-KSKKKRTMSTNS 522

Query: 535 VYTDREDYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLA 594
            YTDRE+  ++ E+ EDF VEG+ATV+RAIEN+HDLDTALLELNTLRMS+NV+YHEVR  
Sbjct: 523 AYTDREEDPTEFEDEEDFGVEGVATVKRAIENNHDLDTALLELNTLRMSLNVSYHEVRTV 582

Query: 595 TATALVRRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQK 654
           T  AL+ RVYHFI TQTLGPK+A  KVF +WG +F R+ F+P+EY+DLMNI+ME + EQ+
Sbjct: 583 TVVALLDRVYHFIATQTLGPKDAANKVFTRWGPMFRREAFDPDEYVDLMNIVMEQVVEQE 642

Query: 655 FEKPEFILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKWVDWLRNAE 711
            EK + ILFSA N LYD+DILEE+ IY+WW +VS+D K+D +K L AKW++WL+ A+
Sbjct: 643 LEKGDLILFSAFNALYDSDILEEEIIYDWWSHVSKDPKFDDIKKLVAKWIEWLKEAD 699


>|KLTH0F07942p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
           initiation factor eIF2B the guanine-nucleotide exchange
           factor for eIF2 activity subsequently regulated by
           phosphorylated eIF2 first identified as a negative
           regulator of GCN4 expression : similar to uniprot|P32501
           Saccharomyces cerevisiae [Kluyveromyces thermotolerans]
          Length = 726

 Score =  936 bits (2420), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 458/719 (63%), Positives = 575/719 (79%), Gaps = 15/719 (2%)

Query: 1   MAGKKGK----GVPPKKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLI 56
           MAGKKGK     V   K  ++  ++RLQA+VLTDS+ETRFMPLTA KPRCL+PLANVPLI
Sbjct: 1   MAGKKGKTPKKSVGGGKKPEVVQDERLQAIVLTDSFETRFMPLTAVKPRCLLPLANVPLI 60

Query: 57  EYTLEFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMR 116
           EYTLEFLAKAGA EV+L C++HA QV  YIE SKWN+PWSPF+V+T+M+ E+RS+GD MR
Sbjct: 61  EYTLEFLAKAGASEVYLVCASHADQVSAYIETSKWNMPWSPFRVSTIMSLESRSVGDAMR 120

Query: 117 DLDNRGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTI 176
           DLDNRG+ITGDFILVSGD+VTN++F K L FH++  A+DKDHI TMCL+KASQ+Y TR  
Sbjct: 121 DLDNRGVITGDFILVSGDLVTNMEFDKALEFHRKKKAEDKDHIVTMCLSKASQFYRTRCH 180

Query: 177 EPACFVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTP 236
           EPA F+L+KS NRCLYYQD+P  +S+ +  L +DPELLE+VD F++RNDLIDC +DIC+P
Sbjct: 181 EPAAFILDKSNNRCLYYQDIPLASSKHKTSLAIDPELLEDVDEFTLRNDLIDCHVDICSP 240

Query: 237 HVPPIFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLG 296
            VP IFQ+NFDYQ LR DF+KGV++SDLL K IY++ITDEYA R ESW ++D ISQDF+ 
Sbjct: 241 LVPAIFQENFDYQYLRRDFVKGVLTSDLLKKSIYSFITDEYAARVESWQTYDAISQDFIA 300

Query: 297 RLCYPLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENC 356
           R CYP+VL +N+ +DQTYSYES HIYKEKDVVLAQSCKIGK TAIG+G+KIGE T ++N 
Sbjct: 301 RWCYPMVLNTNLLDDQTYSYESEHIYKEKDVVLAQSCKIGKRTAIGSGSKIGEGTKIQNS 360

Query: 357 VIGRNCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVI 416
           VIGRNC IGENI I++S+IWDNTVIG    I H +VAS  K+G+NVILNDGC+IGF+V++
Sbjct: 361 VIGRNCYIGENIIIRDSFIWDNTVIGAKSLIEHSLVASGVKIGSNVILNDGCVIGFNVMV 420

Query: 417 EDNKEIPAGSKISSVPVASSRSRLPASDGYDDEDDDEEYSETFDDTTQQ-ALASELVGEH 475
           +DN EIP G++IS  PV    ++   S  Y+D++  ++     D++T+  + A ELVG  
Sbjct: 421 DDNMEIPMGTRISETPVRKKATQFSDSASYEDDETAKQ-----DESTKVISPAYELVGTD 475

Query: 476 GVGYVYESDASDIEEYDEDECFKIV-NSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNS 534
           GVGYVY+SD ++ ++  +     +V NSL  + +D+YLSD+SISST  + KKKR+MSTNS
Sbjct: 476 GVGYVYDSDKAEDDD--DASVIDVVTNSLTYKFDDLYLSDDSISSTAGKRKKKRSMSTNS 533

Query: 535 VYT--DREDYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVR 592
           +YT  + +DY  DEE+ EDF VE IATVERA+EN+HDLDTALLELNTLRMS+NV+YHEVR
Sbjct: 534 IYTDREGDDYEDDEEDEEDFAVEAIATVERAMENNHDLDTALLELNTLRMSINVSYHEVR 593

Query: 593 LATATALVRRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAE 652
            AT  AL+RRVYHFI TQTLG K+AV KVF QWG +F RQ F+ EE++DL N+L+E +  
Sbjct: 594 SATVVALLRRVYHFIATQTLGAKDAVQKVFSQWGMMFQRQAFDQEEFVDLSNLLLEKVVA 653

Query: 653 QKFEKPEFILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKWVDWLRNAE 711
           Q FEKPEFILFSAL  LYD DIL+ED++Y WWD VSQ+ KY Q KTLTAKW++WL+ A+
Sbjct: 654 QGFEKPEFILFSALTCLYDLDILDEDAVYTWWDQVSQEEKYSQAKTLTAKWIEWLKTAD 712


>|KLLA0A04235p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
           initiation factor eIF2B the guanine-nucleotide exchange
           factor for eIF2 activity subsequently regulated by
           phosphorylated eIF2 first identified as a negative
           regulator of GCN4 expression : similar to uniprot|P32501
           Saccharomyces cerevisiae [Kluyveromyces lactis NRRL
           Y-1140]
          Length = 736

 Score =  904 bits (2335), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 442/727 (60%), Positives = 555/727 (76%), Gaps = 22/727 (3%)

Query: 1   MAGKKGKGVPPKKNDDMDV--EDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEY 58
           M+GKK K     +N   +V  ++RLQA+VLTDS+ETRFMPLT+ KPRCL+PLAN+PLIEY
Sbjct: 1   MSGKKTKSGKANQNKKQEVVQDERLQAIVLTDSFETRFMPLTSVKPRCLLPLANIPLIEY 60

Query: 59  TLEFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDL 118
           TLEFLAKAG +EV+L C++H +Q+ EYI+QSKW+LPW+PFKV T+M+ E+RS+GD MRD+
Sbjct: 61  TLEFLAKAGVNEVYLICASHGEQIQEYIDQSKWSLPWAPFKVNTIMSLESRSVGDAMRDV 120

Query: 119 DNRGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTIEP 178
           DNRG+ITGDF+LVSGD+VTN+DF K L  HK+    DKDHI TMCL+KA+Q++ TR+ EP
Sbjct: 121 DNRGLITGDFVLVSGDLVTNMDFEKALDIHKQRRKADKDHIVTMCLSKATQFHKTRSHEP 180

Query: 179 ACFVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTPHV 238
           A F+ +KS +RC+YYQD+P  +SR +  +D+DPELLE VD F +RNDLIDC +DIC+PHV
Sbjct: 181 ATFIFDKSNDRCIYYQDIPLASSREKTTIDIDPELLEGVDEFVLRNDLIDCHVDICSPHV 240

Query: 239 PPIFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLGRL 298
           P IFQ+NFDYQ LR DF++GV+SSDLL KHIY YITDEY  RAESW ++D ISQDF+ R 
Sbjct: 241 PAIFQENFDYQFLRRDFVRGVLSSDLLKKHIYGYITDEYTTRAESWQTYDAISQDFIARW 300

Query: 299 CYPLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVI 358
           CYPLVL +N+ + QTYSYES HIYKEKDVVLAQSCKI K TAIG+G+KIGE TV+EN V+
Sbjct: 301 CYPLVLNANLLKGQTYSYESQHIYKEKDVVLAQSCKIKKNTAIGSGSKIGEGTVIENSVV 360

Query: 359 GRNCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVIED 418
           GRNC IG NI IKNSYIWDN VI +   I H +VAS+ K+G+NV LNDG IIGF+VVI+D
Sbjct: 361 GRNCKIGSNIRIKNSYIWDNVVIDDNTTIEHSLVASDVKLGSNVTLNDGSIIGFNVVIDD 420

Query: 419 NKEIPAGSKISSVPVASSRSR-LPASDGYDDEDDDEEYSETFDDT--------------T 463
           N  IP G+KIS+VPV  + ++ L  +      D+DEE S TF                  
Sbjct: 421 NVTIPVGTKISAVPVQRNTAQFLDTAHNLSSSDEDEEGS-TFTRNSSSLSISNSDEVADA 479

Query: 464 QQALASELVGEHGVGYVYESDASDIEEYDEDECFKIVNSLRQQVEDIYLSDNSISSTKRR 523
           +  L+ +LVG +G G +YESD  D +E    E   I N+L  + +DIYLSD SISS  ++
Sbjct: 480 KIKLSKQLVGPNGRGVLYESDDEDEDEDGSTEK-GIANTLTYRDDDIYLSDTSISSITQK 538

Query: 524 TKKKRTMSTNSVYTDREDYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMS 583
            +K+RTMS  S+YTD E    +EE+ E    E IATVERAIEN+HDLDT++LELNTLRMS
Sbjct: 539 HRKRRTMSMTSIYTDYEGEEDEEEDFE---KEAIATVERAIENNHDLDTSMLELNTLRMS 595

Query: 584 MNVTYHEVRLATATALVRRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLM 643
           MNVTYHEVR A+  A+ RRVYHF+ TQTLGPK+AV KV  QWG +F RQ F+ +E++DLM
Sbjct: 596 MNVTYHEVRNASVIAIFRRVYHFVATQTLGPKDAVTKVLQQWGPVFKRQAFDSDEFIDLM 655

Query: 644 NILMEIIAEQKFEKPEFILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKW 703
           NI+++ + +QKF+KP+FILF   N LYD DILEED IY+WWD+VS DSKY +V  L AKW
Sbjct: 656 NIILDRVLDQKFDKPDFILFHVYNVLYDLDILEEDVIYKWWDSVSGDSKYSEVTALLAKW 715

Query: 704 VDWLRNA 710
           VDWL+ A
Sbjct: 716 VDWLKTA 722


>|ERGO0G06292p Syntenic homolog of Saccharomyces cerevisiae YDR211W (GCD6)
           [Eremothecium gossypii]
          Length = 731

 Score =  873 bits (2255), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 433/719 (60%), Positives = 550/719 (76%), Gaps = 11/719 (1%)

Query: 1   MAGKK-------GKGVPPKKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANV 53
           MAGKK       G      K +++  ++RLQAVVLTDS+ETRFMPLT   PRCLMPLANV
Sbjct: 1   MAGKKQRAKGQSGNANSAGKRNEVVQDERLQAVVLTDSFETRFMPLTYEMPRCLMPLANV 60

Query: 54  PLIEYTLEFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGD 113
           PLIEYTLEFLAKAG  EV+L C++HA+QV EYI+ SKWNLPWSPFKV+T++  EARS+GD
Sbjct: 61  PLIEYTLEFLAKAGVHEVYLICTSHAEQVQEYIDNSKWNLPWSPFKVSTILALEARSVGD 120

Query: 114 VMRDLDNRGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMT 173
            MRDLDNRG+ITGDFILVSGD+VTN++F + L  H+   A+DK+HI TMCL+ A+Q + T
Sbjct: 121 AMRDLDNRGLITGDFILVSGDLVTNMEFDRALEAHRARRAEDKEHIVTMCLSTATQSHRT 180

Query: 174 RTIEPACFVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDI 233
           R+ EPA F+L+KS +RCLYYQD+P  +S+ +  +D+DPELLE V+ F +RNDLIDC IDI
Sbjct: 181 RSCEPAVFMLDKSNDRCLYYQDIPLASSKRKTAVDIDPELLEGVEEFKLRNDLIDCHIDI 240

Query: 234 CTPHVPPIFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQD 293
           C+P VP IFQ+NFDYQ LR DF+KGV+SSDLL KHIYAYIT EYA R ESW ++D ISQD
Sbjct: 241 CSPLVPAIFQENFDYQYLRRDFVKGVLSSDLLKKHIYAYITKEYAARVESWQTYDAISQD 300

Query: 294 FLGRLCYPLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVV 353
           FL R CYPLVL+SN+ EDQTYSYES H+YKEKDV+LAQSCKIGKCTAIG+G+ IGE T +
Sbjct: 301 FLARWCYPLVLDSNLLEDQTYSYESKHVYKEKDVILAQSCKIGKCTAIGSGSTIGEGTFI 360

Query: 354 ENCVIGRNCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFD 413
           EN VIGRNC IG N+ I NSYIW+N++IG+   ++H IVA+  K+G+ V L DGC+IGF+
Sbjct: 361 ENSVIGRNCQIGANVKIINSYIWENSIIGDNSVLNHSIVAAGAKLGSAVTLEDGCVIGFN 420

Query: 414 VVIEDNKEIPAGSKISSVPVASSRSRLPASDGYDDEDDDEEYSETFDDTTQQ--ALASEL 471
           VV+  +K IP+G++IS+ P+  S   +P +  Y  ++D +E S     T  +  A A +L
Sbjct: 421 VVVASSKTIPSGTRISAAPITVSSMSVP-TPSYSSDEDSDEDSGLHPATRSKSTAKAVQL 479

Query: 472 VGEHGVGYVYESDASDIEEYDEDECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMS 531
           VGE GVGY+YESD SD  E  +D      N+L  +++++YLSD+SI S   +TKK+RT+S
Sbjct: 480 VGESGVGYIYESDDSDDSEETDDCDGAGANTLCTRMDELYLSDSSIYSAS-KTKKRRTLS 538

Query: 532 TNSVYTDREDYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEV 591
           T S YTD ED     EE EDF  E IATVERA+E++HD+DTALLELNTLRMS+NVTYHEV
Sbjct: 539 TASYYTDWEDGSDASEEEEDFEKEAIATVERAMEHNHDIDTALLELNTLRMSLNVTYHEV 598

Query: 592 RLATATALVRRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIA 651
           R AT +A+++RVYHFI TQTLGPK+AV KVF  WG LF RQ F   EY+DLM++++  + 
Sbjct: 599 RAATVSAMLKRVYHFIATQTLGPKDAVAKVFAHWGPLFRRQAFTAAEYVDLMDVILHRVV 658

Query: 652 EQKFEKPEFILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYDQVKTLTAKWVDWLRNA 710
             +F++P+FILF   + LYD+DIL+ED +Y+WW   + D  +  VKTLTAKWVDWL+ A
Sbjct: 659 SMRFDRPDFILFCVYSCLYDSDILDEDVVYQWWAAAAADPAHADVKTLTAKWVDWLQTA 717


>|DEHA2G14322p (infer) YDR211W GCD6 Catalytic epsilon subunit of the translation
           initiation factor eIF2B the guanine-nucleotide exchange
           factor for eIF2 : similar to uniprot|P32501
           Saccharomyces cerevisiae [Debaryomyces hansenii CBS767]
          Length = 730

 Score =  729 bits (1881), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 378/715 (52%), Positives = 500/715 (69%), Gaps = 19/715 (2%)

Query: 12  KKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEYTLEFLAKAGADEV 71
           KK  ++  +DR QA+VLTDS+ETRFMPLT+  PRCL+PLANVPLIEYTLEFLA AG +EV
Sbjct: 6   KKQKEIVQDDRFQAIVLTDSFETRFMPLTSILPRCLLPLANVPLIEYTLEFLANAGVNEV 65

Query: 72  FLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDNRGIITGDFILV 131
           +L CS+HA Q+ EYIE+SKW+   SPFK++T+M+ E+RS+GD MRDLDNRG+I+GDF+LV
Sbjct: 66  YLMCSSHADQIQEYIEKSKWSSKNSPFKISTIMSLESRSVGDAMRDLDNRGLISGDFLLV 125

Query: 132 SGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRT-IEPACFVLEKSTNRC 190
           SGDVVTNIDF K ++ HK+    DKDHI TM L  AS  + TR+ ++PA F+L+K+T RC
Sbjct: 126 SGDVVTNIDFEKAMNAHKQRKQMDKDHIVTMVLTPASPLHRTRSQVDPATFILDKNTGRC 185

Query: 191 LYYQDMPSPNSRSRKVLDVDPELLENV-DSFSMRNDLIDCRIDICTPHVPPIFQDNFDYQ 249
           ++YQ +P P    R  +++DPELLE++ D   +RNDLIDC +DIC+PHVP IFQ+NFDYQ
Sbjct: 186 VFYQGIP-PVDGKRSSINIDPELLEDIEDEMVIRNDLIDCCVDICSPHVPQIFQENFDYQ 244

Query: 250 SLRSDFLKGVISSDLLGKHIYAYITD--EYAVRAESWHSFDTISQDFLGRLCYPLVLESN 307
            LRSDF+KGV++SDLL K IYAYITD  EYA R ESW ++D +SQD L R CYPLV +SN
Sbjct: 245 YLRSDFVKGVLTSDLLKKTIYAYITDGSEYAARVESWATYDAVSQDVLARWCYPLVPDSN 304

Query: 308 IQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVIGRNCIIGEN 367
           + E  +YSYE  HIYKE  V+LAQSCKIG CT+IG  + +GE T ++  VIGRNC IG N
Sbjct: 305 LLESNSYSYEFNHIYKEDKVILAQSCKIGSCTSIGTNSSVGEGTSIKKSVIGRNCQIGNN 364

Query: 368 INIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVIEDNKEIPAGSK 427
           + I NSYIWDN +I +   + H I+A N ++G+   L+ G +IG++VVI D   +   ++
Sbjct: 365 VTINNSYIWDNAIIKDDSVVDHSIIAGNAEIGSGATLSPGTVIGYNVVIGDGIHLSNNTR 424

Query: 428 ISSVPVASSRSRLPASDGYDDEDDDEEYSET-FDDTTQQALASELVGEHGVGYVYESDAS 486
           I   P+        +S  +D E +D + +   + +  Q     ++VG++GVG++Y SD  
Sbjct: 425 IVEKPIDRDDESFESSRSFDSEQEDGKTNGGEYINADQSVNDIDVVGDNGVGFLYVSDNE 484

Query: 487 DIEEYD-EDECFKIVNSLRQQVEDIYLSDNSISSTK--------RRT--KKKRTMSTNSV 535
             EE D E       + +  Q+  + +SD+SI+S          RRT  + +R  S + V
Sbjct: 485 LDEESDSEYGVSHNYSGIIYQMSSLNVSDDSIASVSNAKSKKFHRRTSSRNRRLSSASMV 544

Query: 536 YTDREDYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLAT 595
            TD E     EEE EDF  E IATV+R++EN+HDLDTALLELNTLRMSMNVTYHEVRLAT
Sbjct: 545 STDYEGGPFSEEEDEDFEKEAIATVDRSMENNHDLDTALLELNTLRMSMNVTYHEVRLAT 604

Query: 596 ATALVRRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQKF 655
           + AL+ ++ HFI T TL  KEA  K+F +WG LF RQVFE  E +DL+ I+ ++ +    
Sbjct: 605 SKALIHKIIHFITTDTLDVKEATEKIFNKWGLLFKRQVFEEFEQVDLLQIIQDVCSNVDK 664

Query: 656 EKPEFILFSALNTLYDNDILEEDSIYEWWDNVSQDSKYD--QVKTLTAKWVDWLR 708
                ILF ALN LY+ DI+EE++IY+WWD+ S  +  D  QV+TLT KWVDWLR
Sbjct: 665 SYNGRILFMALNILYNQDIVEEENIYKWWDSESSTANDDLVQVRTLTGKWVDWLR 719


>|YALI0B15708p (infer) YDR211w GCD6 translation initiation factor eIF2b epsilon 81
           kDa subunit : similar to uniprot|P32501 Saccharomyces
           cerevisiae [Yarrowia lipolytica CLIB122]
          Length = 681

 Score =  504 bits (1298), Expect = e-142,   Method: Compositional matrix adjust.
 Identities = 286/715 (40%), Positives = 422/715 (59%), Gaps = 56/715 (7%)

Query: 1   MAGKKGKGVPPKKNDDMDVEDRLQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEYTL 60
           M  KK    P K   D D   RLQAV+L DSY+ RF PLT   PRCL+PLAN PL+EYT 
Sbjct: 1   MPPKKKNAKPQKSAIDKDF--RLQAVILADSYQARFQPLTKDYPRCLLPLANTPLLEYTF 58

Query: 61  EFLAKAGADEVFLACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDN 120
           EFLAKAG  EVFL C +HA +++EYI+ SKW+   SPF++ T    E+ S+GD MRDLD 
Sbjct: 59  EFLAKAGVCEVFLMCCSHADKIEEYIKTSKWSDSHSPFEIHTKKLTESMSVGDAMRDLDG 118

Query: 121 RGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRT-IEPA 179
            G IT DF+LVSGDVV+NIDF+ +L  H +    DK+ + TM L +A  ++ TR+ IEP 
Sbjct: 119 TGSITSDFLLVSGDVVSNIDFTPVLEQHLQRKQDDKNAMMTMVLRQADAFHRTRSRIEPG 178

Query: 180 CFVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTPHVP 239
            FVL   T+ CL Y+++   N      +D+D ELL +  + S+RNDLIDC ID+C+  V 
Sbjct: 179 LFVLNDKTSECLRYEELSLNNPTGS--IDLDGELLNDDATLSIRNDLIDCHIDLCSIDVL 236

Query: 240 PIFQDNFDYQSLRSDFLKGVISSDLLGKHIYAYI-TDEYAVRAESWHSFDTISQDFLGRL 298
             F +NFDY +LRSDF+K +++S++LGK IYA+I TD YA R  S  ++  +++D + R 
Sbjct: 237 AQFTENFDYSTLRSDFVKNILTSEILGKKIYAHIVTDAYAARVRSLQTYSAVTKDIVSRY 296

Query: 299 CYPLVLESNIQEDQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVI 358
            YP+V +SN+ +DQT+SY+ GHIYKEK VVLAQSC IG  + +G GT +GER++V++ VI
Sbjct: 297 SYPVVPDSNLMDDQTFSYQMGHIYKEKGVVLAQSCVIGSRSLVGRGTSVGERSMVKDTVI 356

Query: 359 GRNCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILNDGCIIGFDVVIED 418
           GR+C I  N+N+ +S+IW N +I +   ++  +VA    +     +  G IIG  V +E+
Sbjct: 357 GRDCKISTNVNLVDSFIWSNVIIEDDVTVNGGLVADGAILKKGCSVGPGSIIGHGVTVEE 416

Query: 419 NKEIPAGSKISSVPVASSRSRLPASDGYDDEDDDEEYSETFDDTTQQALASELVGEHGVG 478
            ++I       +  V  +   +P             +    DD +      E     G  
Sbjct: 417 GQKIEG-----TYLVLDAGESIP-------------FDAIDDDDSDFDTDDEFNANVG-S 457

Query: 479 YVYESDASDIEEYD-EDECFKIVNSLRQQVEDIYLSDNSISSTKRRTKKKRTMSTNSVYT 537
            VY     ++ +    D C++   ++R           +++  K+ T+++ + + ++V  
Sbjct: 458 LVYNLKELNLSDTSINDHCYEDDENIR-----------AVAPKKK-TRRRLSSTVSNVSD 505

Query: 538 DREDYLSDEEEGEDFLVEGIATVERAIENDHDLDTALLELNTLRMSMNVTYHEVRLATAT 597
           + ED         +F  E IA+++RA +++H++D A LEL TLRMS NV Y EVR A+  
Sbjct: 506 NHED---------EFQKEAIASLDRAFQDNHEIDIAALELGTLRMSSNVPYEEVRAASVK 556

Query: 598 AL---VRRVYHFIETQTLGPKEAVPKVFGQWGALFNRQVFEPEEYLDLMNILMEIIAEQK 654
           A+   + RV +   T     K    KV+G+W  LF +QVFEP + +DL+NIL++  + + 
Sbjct: 557 AINGYITRVLNMGVTD--DHKVPTQKVWGKWAELFEKQVFEPADQIDLLNILLKDCSRRP 614

Query: 655 FEKPEFILFSALNTLYDNDILEEDSIYEWWDNVSQD--SKYDQVKTLTAKWVDWL 707
                +ILF+A+ +LYD D+L+E  I  WW    +D   +   V+TL  KWV WL
Sbjct: 615 V--GNYILFAAVQSLYDADVLDEHVIVRWWHQQPEDVSPEIASVRTLLGKWVTWL 667


>|YALI0C06490p (infer) CaPSA1 Mannose-1-phosphate guanyltransferase (EC |2.7.7.13)
           : highly similar to uniprot|O93827 Candida albicans
           [Yarrowia lipolytica CLIB122]
          Length = 363

 Score = 63.5 bits (153), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 83/401 (20%), Positives = 162/401 (40%), Gaps = 67/401 (16%)

Query: 23  LQAVVLTDSYETRFMPLTASKPRCLMPLANVPLIEYTLEFLAKAGADEVFLACSAHAKQV 82
           ++ ++L   Y TR  PLT + P+ L+   N P+I + +E LA AG  ++ LA +   + +
Sbjct: 1   MKGLILVGGYGTRLRPLTLTLPKPLVEFGNKPMILHQVESLAAAGVKDIVLAVNYRPEVM 60

Query: 83  DEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDNRGIITGD---FILVSGDVVTNI 139
            E +++ +       + V    + E   +G          I+  D   F +++ DV+ + 
Sbjct: 61  IETLKKYEEK-----YGVNITFSVETEPLGTAGPLKLAEEILCKDDTPFFVLNSDVICDY 115

Query: 140 DFSKMLSFHKEMHAKDKDHIATMCLNKASQYYMTRTIEPACFVLEKSTNRCLYYQDMP-- 197
            F+++  FHK+ +A+    I    + + S+Y           V ++ T++   + + P  
Sbjct: 116 PFAELAEFHKKNNAEAT--IVATKVEEPSKY--------GVIVHKQGTSKIDRFVEKPVE 165

Query: 198 -SPNSRSRKVLDVDPELLENVDSFSMRNDLIDCRIDICTPHVPPIFQDNFDYQSLRSDFL 256
              N  +  +  ++P ++          DLID R          I ++ F   + R    
Sbjct: 166 FVGNRINAGIYILNPSVV----------DLIDLRPT-------SIEKETFPQLAAR---- 204

Query: 257 KGVISSDLLGKHIYAYITDEYAVRAESWHSFDTISQDFLGRLCYPLV------LESNIQE 310
                     + +Y++  + Y      W       +DFL   C  L        E+ +  
Sbjct: 205 ----------ESLYSFDLEGY------WMDVGQ-PKDFLSGTCLYLSSLSKKNPEALVPT 247

Query: 311 DQTYSYESGHIYKEKDVVLAQSCKIGKCTAIGAGTKIGERTVVENCVIGRNCIIGENINI 370
            + Y    G++  +    ++   KIG    IG G  IGE   +  CV+  N  I  +  +
Sbjct: 248 SEPY-VTGGNVLVDPTAKISPQAKIGPNVVIGPGAVIGEGARLSRCVVLANSTIKPHAFV 306

Query: 371 KNSYIWDNTVIGNGCNISHC-IVASNTKMGANVILNDGCII 410
           KNS I  N  +G    I +  +   + ++   V +N G ++
Sbjct: 307 KNSIIGWNGRVGRWARIENVSVFGDDVEVKDEVYVNGGRVL 347


>|YALI0E21846p (infer) YOR260w GCD1 translation initiation factor eIF2bgamma
           subunit : similar to uniprot|P09032 Saccharomyces
           cerevisiae [Yarrowia lipolytica CLIB122]
          Length = 483

 Score = 63.5 bits (153), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 102/462 (22%), Positives = 179/462 (38%), Gaps = 119/462 (25%)

Query: 44  PRCLMPLANVPLIEYTLEFLAKAGADEVFLACS-AHAKQVDEYIEQSKWNLPWS--PFKV 100
           P+ L+P+ANVP+I+YTL++       +VF+ CS A   ++  Y++  K     S     V
Sbjct: 29  PKALLPMANVPVIDYTLKWCETIPNPKVFVCCSTADEAEISAYVDSFKAEHSTSVVASNV 88

Query: 101 TTLMNPEARSIGDVMRDLDNRGIITGDFILVSGDVVTNIDFSKMLSFHKEMHAKDKDHIA 160
           T     +A+S GD + +L  RG    DFI+V  D +T+I  S ++  ++   ++D D + 
Sbjct: 89  TICSKTDAKS-GDFILEL-TRG-EPSDFIVVGCDFITDIPASSLVDTYR---SRDSDSLL 142

Query: 161 TMCLNKASQYYMTRTIEPACFVLEKSTNRCLYYQDMPSPNSRSRKVLDVDPELLENVDSF 220
           T                              YY                 P  LENVD  
Sbjct: 143 TA----------------------------FYY-----------------PNTLENVDKK 157

Query: 221 SMRNDL-IDCRIDICTPHVPPIFQDNF--------DYQSLRSDFLKGVISSDLLGKHIYA 271
           S+  D+ +   +D  TP +   +  ++          +S+   F K ++S+ LL   +Y 
Sbjct: 158 SLLKDVTVHSSLDSRTPRLLDSYSRDYIENKKTMPIRRSMLWHFPKSLVSTQLLNASVYF 217

Query: 272 YITDEYAVRAESWHS----------------------------------FDTISQDFLGR 297
              D   V  E+  +                                  +D + +D   R
Sbjct: 218 CTADVCRVITETQAAPEEDSTDEDPDTRSSSPVRQEQEEAHTILAKGRQWDRVVRDIARR 277

Query: 298 L---CYPL------VLESNIQEDQTYSYESG-HIYKEKDVVLAQSCKIGKCTAIGAGTKI 347
                 PL      VL+SN     T++  +    Y E + V+ ++      TA      +
Sbjct: 278 SWAHAKPLKSVSLCVLDSN-----TFARANNLSAYMEMNRVILKARAKANATAQKPAPAV 332

Query: 348 -GERTVVENCVIGRNCIIGENINIKNSYIWDNTVIGNGCNISHCIVASNTKMGANVILND 406
            G  TV  + ++G    +GE  +IK S + +N  IG  C I+ C++     +  +V L +
Sbjct: 333 KGAATVGVDSLVGEETQLGERTSIKRSVVGNNCTIGKRCRINGCVIFDGAFIADDVTL-E 391

Query: 407 GCIIGFDVVIEDNKE-----IPAGSKISSVPVASSRSRLPAS 443
            C++G    +    +     +  G K+ +  VA + + L  S
Sbjct: 392 NCLVGTKTTVGTKAKLTGCNVEGGYKVEAGKVAKNETMLQLS 433


>|DEHA2E15862p (infer) YDL055C PSA1 GDP-mannose pyrophosphorylase
           (mannose-1-phosphate guanyltransferase) synthesizes GDP-
           mannose from GTP and mannose-1-phosphate in cell wall
           biosynthesis : weakly similar to uniprot|P41940
           Saccharomyces cerevisiae [Debaryomyces hansenii CBS767]
          Length = 509

 Score = 58.9 bits (141), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 15/145 (10%)

Query: 20  EDRLQAVVLT--DSYETRFMPLTASKPRCLMPLANVPLIEYTLEFLAKAGADEV----FL 73
           E  L+ V+L   ++  TRF PL+   P+ L P+A  PLI + ++ +A+ G  E+     L
Sbjct: 53  EMSLKVVILIGGETTGTRFRPLSMDTPKVLFPIAGKPLISHIVQKIAELGEGELIEVFLL 112

Query: 74  ACSAHAKQVDEYIEQSKWNLPWSPFKVTTLMNPEARSIGDVMRDLDNRGIITGD-----F 128
                 K  DEYI ++K    +S   +  L  P +   G  +     R  I GD      
Sbjct: 113 GYFTDLKPFDEYIAEAKKE--YSNVNIKYLTEPYSMGTGGGLYYF--RDEIFGDGTCEEL 168

Query: 129 ILVSGDVVTNIDFSKMLSFHKEMHA 153
           +++ GD+V N  F +++ F+K+ +A
Sbjct: 169 LVIHGDIVCNYPFKELIQFYKKSNA 193



BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.